Myelodysplastic Syndrome (MONDO:0018881)
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)
Overview
Mapped terms
DOID:0050908
EFO:0000198
GARD:0007132
ICD10CM:D46
ICD9:238.7
ICD9:238.75
ICDO:9989/3
MEDGEN:483005
MedDRA:10028532
NANDO:2100003
NANDO:2200019
NCIT:C3247
NORD:1480
OMIM:614286
ONCOTREE:MDS
Orphanet:52688
SCTID:109995007
UMLS:C3463824
Child terms