[
  {
    "phenotype_id": "PH4405",
    "phenotype_version_id": 9624,
    "name": "Falls Risk Increasing Drugs (FRIDs)",
    "definition": "This phenotype identifies individuals prescribed falls risk increasing drugs (FRIDs) in routinely collected electronic health records. FRIDs are medications associated with an increased risk of falls through effects such as sedation, dizziness, impaired cognition, orthostatic hypotension, or impaired motor function. The phenotype is intended for use in studies of falls risk assessment, epidemiology, risk prediction, and evaluation of fall prevention interventions. Case ascertainment is based on prescribing records for medication classes recognised as increasing falls risk.\n",
    "implementation": "",
    "publications": [
      {
        "doi": "10.1038/s41598-026-55527-4",
        "details": "Lear, R., Tao, R., Carenzo, C. et al. Identifying high-risk patient clusters for falls using unsupervised machine learning on linked primary and secondary care electronic health record data. Sci Rep (2026).",
        "primary": 1
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2026-07-10T11:50:02.384182Z",
    "author": "Rachael Lear, Rachel Tao, Catalina Carenzo, Ekin Yagis, Zhuoyu Li, Maria Tipper, Agnes Motsi, Sharon O’Malley, Yusuf Abdullahi, Ben Glampson, Colin Mitchell, Erik K Mayer",
    "collections": null,
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2026-07-10T11:50:02.376118Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Drug",
        "value": "3"
      }
    ],
    "ontology": null,
    "phenoflowid": "",
    "data_sources": null,
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      }
    ],
    "event_date_range": "",
    "concept_information": [
      {
        "concept_id": 11450,
        "concept_version_id": 18935,
        "concept_name": "fall-risk-factor/frids",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH4405",
        "phenotype_version_id": 9624,
        "phenotype_name": "Falls Risk Increasing Drugs (FRIDs)",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "372490001",
            "description": "VENLAFAXINE",
            "attributes": null
          },
          {
            "code": "372508002",
            "description": "DOXAZOSIN",
            "attributes": null
          },
          {
            "code": "372509005",
            "description": "TAMSULOSIN",
            "attributes": null
          },
          {
            "code": "372510000",
            "description": "FOSINOPRIL",
            "attributes": null
          },
          {
            "code": "372512008",
            "description": "CANDESARTAN",
            "attributes": null
          },
          {
            "code": "372570008",
            "description": "TOLTERODINE",
            "attributes": null
          },
          {
            "code": "372587005",
            "description": "DOXEPIN",
            "attributes": null
          },
          {
            "code": "372594008",
            "description": "SERTRALINE",
            "attributes": null
          },
          {
            "code": "372595009",
            "description": "PAROXETINE",
            "attributes": null
          },
          {
            "code": "372596005",
            "description": "CITALOPRAM",
            "attributes": null
          },
          {
            "code": "372652004",
            "description": "NORTRIPTYLINE",
            "attributes": null
          },
          {
            "code": "372658000",
            "description": "ENALAPRIL",
            "attributes": null
          },
          {
            "code": "372682005",
            "description": "DIPHENHYDRAMINE",
            "attributes": null
          },
          {
            "code": "372714007",
            "description": "ORPHENADRINE",
            "attributes": null
          },
          {
            "code": "372717000",
            "description": "OXYBUTYNIN",
            "attributes": null
          },
          {
            "code": "372718005",
            "description": "IMIPRAMINE",
            "attributes": null
          },
          {
            "code": "372726002",
            "description": "AMITRIPTYLINE",
            "attributes": null
          },
          {
            "code": "372730004",
            "description": "FLUPHENAZINE",
            "attributes": null
          },
          {
            "code": "372741002",
            "description": "PROMAZINE",
            "attributes": null
          },
          {
            "code": "372751001",
            "description": "FLECAINIDE",
            "attributes": null
          },
          {
            "code": "372754009",
            "description": "VERAPAMIL",
            "attributes": null
          },
          {
            "code": "372767007",
            "description": "FLUOXETINE",
            "attributes": null
          },
          {
            "code": "372772003",
            "description": "PROPRANOLOL",
            "attributes": null
          },
          {
            "code": "372793000",
            "description": "DILTIAZEM",
            "attributes": null
          },
          {
            "code": "372805007",
            "description": "CLONIDINE",
            "attributes": null
          },
          {
            "code": "372819007",
            "description": "DANTROLENE",
            "attributes": null
          },
          {
            "code": "372821002",
            "description": "AMIODARONE",
            "attributes": null
          },
          {
            "code": "372826007",
            "description": "METOPROLOL",
            "attributes": null
          },
          {
            "code": "372829000",
            "description": "TRAZODONE",
            "attributes": null
          },
          {
            "code": "372853006",
            "description": "PROCHLORPERAZINE",
            "attributes": null
          },
          {
            "code": "372866006",
            "description": "CHLORDIAZEPOXIDE",
            "attributes": null
          },
          {
            "code": "372871004",
            "description": "PROMETHAZINE",
            "attributes": null
          },
          {
            "code": "372880004",
            "description": "TIMOLOL",
            "attributes": null
          },
          {
            "code": "372891006",
            "description": "TRANYLCYPROMINE",
            "attributes": null
          },
          {
            "code": "372903001",
            "description": "CLOMIPRAMINE",
            "attributes": null
          },
          {
            "code": "372911006",
            "description": "SOTALOL",
            "attributes": null
          },
          {
            "code": "372914003",
            "description": "CHLORPHENAMINE",
            "attributes": null
          },
          {
            "code": "372916001",
            "description": "PERINDOPRIL",
            "attributes": null
          },
          {
            "code": "373492002",
            "description": "FENTANYL",
            "attributes": null
          },
          {
            "code": "373505007",
            "description": "PHENOBARBITAL",
            "attributes": null
          },
          {
            "code": "373524005",
            "description": "TRIFLUOPERAZINE",
            "attributes": null
          },
          {
            "code": "373529000",
            "description": "MORPHINE",
            "attributes": null
          },
          {
            "code": "373550009",
            "description": "TRIMIPRAMINE",
            "attributes": null
          },
          {
            "code": "373567002",
            "description": "LOSARTAN",
            "attributes": null
          },
          {
            "code": "386837002",
            "description": "HALOPERIDOL",
            "attributes": null
          },
          {
            "code": "386840002",
            "description": "RISPERIDONE",
            "attributes": null
          },
          {
            "code": "386844006",
            "description": "TOPIRAMATE",
            "attributes": null
          },
          {
            "code": "386845007",
            "description": "GABAPENTIN",
            "attributes": null
          },
          {
            "code": "386847004",
            "description": "MIRTAZAPINE",
            "attributes": null
          },
          {
            "code": "386849001",
            "description": "OLANZAPINE",
            "attributes": null
          },
          {
            "code": "386850001",
            "description": "QUETIAPINE",
            "attributes": null
          },
          {
            "code": "386854005",
            "description": "ISOSORBIDE_MONONITRATE",
            "attributes": null
          },
          {
            "code": "386855006",
            "description": "DONEPEZIL",
            "attributes": null
          },
          {
            "code": "386858008",
            "description": "TRAMADOL",
            "attributes": null
          },
          {
            "code": "386863007",
            "description": "FELODIPINE",
            "attributes": null
          },
          {
            "code": "386864001",
            "description": "AMLODIPINE",
            "attributes": null
          },
          {
            "code": "386868003",
            "description": "BISOPROLOL",
            "attributes": null
          },
          {
            "code": "386870007",
            "description": "CARVEDILOL",
            "attributes": null
          },
          {
            "code": "386871006",
            "description": "TRANDOLAPRIL",
            "attributes": null
          },
          {
            "code": "386872004",
            "description": "RAMIPRIL",
            "attributes": null
          },
          {
            "code": "386873009",
            "description": "LISINOPRIL",
            "attributes": null
          },
          {
            "code": "386874003",
            "description": "QUINAPRIL",
            "attributes": null
          },
          {
            "code": "386876001",
            "description": "VALSARTAN",
            "attributes": null
          },
          {
            "code": "386877005",
            "description": "IRBESARTAN",
            "attributes": null
          },
          {
            "code": "387000003",
            "description": "LEVETIRACETAM",
            "attributes": null
          },
          {
            "code": "387068008",
            "description": "TERAZOSIN",
            "attributes": null
          },
          {
            "code": "387069000",
            "description": "TELMISARTAN",
            "attributes": null
          },
          {
            "code": "387106007",
            "description": "LORAZEPAM",
            "attributes": null
          },
          {
            "code": "387109000",
            "description": "FLURAZEPAM",
            "attributes": null
          },
          {
            "code": "387120000",
            "description": "TRIHEXYPHENIDYL",
            "attributes": null
          },
          {
            "code": "387123003",
            "description": "METOLAZONE",
            "attributes": null
          },
          {
            "code": "387160004",
            "description": "CAPTOPRIL",
            "attributes": null
          },
          {
            "code": "387161000",
            "description": "ISOCARBOXAZID",
            "attributes": null
          },
          {
            "code": "387173000",
            "description": "BUPRENORPHINE",
            "attributes": null
          },
          {
            "code": "387220006",
            "description": "PHENYTOIN",
            "attributes": null
          },
          {
            "code": "387222003",
            "description": "CARBAMAZEPINE",
            "attributes": null
          },
          {
            "code": "387258005",
            "description": "CHLORPROMAZINE",
            "attributes": null
          },
          {
            "code": "387264003",
            "description": "DIAZEPAM",
            "attributes": null
          },
          {
            "code": "387300007",
            "description": "TEMAZEPAM",
            "attributes": null
          },
          {
            "code": "387322000",
            "description": "DIHYDROCODEINE",
            "attributes": null
          },
          {
            "code": "387324004",
            "description": "CHLORTHALIDONE",
            "attributes": null
          },
          {
            "code": "387342009",
            "description": "BACLOFEN",
            "attributes": null
          },
          {
            "code": "387383007",
            "description": "CLONAZEPAM",
            "attributes": null
          },
          {
            "code": "387404004",
            "description": "GLYCERYL_TRINITRATE",
            "attributes": null
          },
          {
            "code": "387419003",
            "description": "INDAPAMIDE",
            "attributes": null
          },
          {
            "code": "387433003",
            "description": "PRAZOSIN",
            "attributes": null
          },
          {
            "code": "387449001",
            "description": "NITRAZEPAM",
            "attributes": null
          },
          {
            "code": "387455006",
            "description": "OXAZEPAM",
            "attributes": null
          },
          {
            "code": "387461009",
            "description": "DIGOXIN",
            "attributes": null
          },
          {
            "code": "387471006",
            "description": "ALIMEMAZINE",
            "attributes": null
          },
          {
            "code": "387475002",
            "description": "FUROSEMIDE",
            "attributes": null
          },
          {
            "code": "387477005",
            "description": "HYOSCINE_HYDROBROMIDE",
            "attributes": null
          },
          {
            "code": "387481005",
            "description": "SODIUM_VALPROATE",
            "attributes": null
          },
          {
            "code": "387490003",
            "description": "NIFEDIPINE",
            "attributes": null
          },
          {
            "code": "387494007",
            "description": "CODEINE",
            "attributes": null
          },
          {
            "code": "387498005",
            "description": "BUMETANIDE",
            "attributes": null
          },
          {
            "code": "387506000",
            "description": "ATENOLOL",
            "attributes": null
          },
          {
            "code": "387520007",
            "description": "BENDROFLUMETHIAZIDE",
            "attributes": null
          },
          {
            "code": "387528000",
            "description": "PHENELZINE",
            "attributes": null
          },
          {
            "code": "387562000",
            "description": "LAMOTRIGINE",
            "attributes": null
          },
          {
            "code": "387565003",
            "description": "MIANSERIN",
            "attributes": null
          },
          {
            "code": "387568001",
            "description": "CLOZAPINE",
            "attributes": null
          },
          {
            "code": "387569009",
            "description": "ZOLPIDEM",
            "attributes": null
          },
          {
            "code": "387570005",
            "description": "LORMETAZEPAM",
            "attributes": null
          },
          {
            "code": "391761004",
            "description": "AMISULPRIDE",
            "attributes": null
          },
          {
            "code": "395727007",
            "description": "GALANTAMINE",
            "attributes": null
          },
          {
            "code": "395739004",
            "description": "HYOSCINE_BUTYLBROMIDE",
            "attributes": null
          },
          {
            "code": "395748009",
            "description": "INDORAMIN",
            "attributes": null
          },
          {
            "code": "395764001",
            "description": "LACIDIPINE",
            "attributes": null
          },
          {
            "code": "395772004",
            "description": "LOFEPRAMINE",
            "attributes": null
          },
          {
            "code": "395805008",
            "description": "MOXONIDINE",
            "attributes": null
          },
          {
            "code": "395809002",
            "description": "NICORANDIL",
            "attributes": null
          },
          {
            "code": "395868008",
            "description": "RIVASTIGMINE",
            "attributes": null
          },
          {
            "code": "395891007",
            "description": "SULPIRIDE",
            "attributes": null
          },
          {
            "code": "395929002",
            "description": "ZOPICLONE",
            "attributes": null
          },
          {
            "code": "395954002",
            "description": "ALFUZOSIN",
            "attributes": null
          },
          {
            "code": "395955001",
            "description": "CINNARIZINE",
            "attributes": null
          },
          {
            "code": "395986007",
            "description": "LERCANIDIPINE",
            "attributes": null
          },
          {
            "code": "396044005",
            "description": "EPROSARTAN",
            "attributes": null
          },
          {
            "code": "400447003",
            "description": "ESCITALOPRAM",
            "attributes": null
          },
          {
            "code": "406784005",
            "description": "ARIPRAZOLE",
            "attributes": null
          },
          {
            "code": "407030007",
            "description": "SOLIFENACIN",
            "attributes": null
          },
          {
            "code": "407032004",
            "description": "DULOXETINE",
            "attributes": null
          },
          {
            "code": "412259001",
            "description": "OLMESARTAN",
            "attributes": null
          },
          {
            "code": "414047005",
            "description": "DOSULEPIN",
            "attributes": null
          },
          {
            "code": "415160008",
            "description": "PREGABALIN",
            "attributes": null
          },
          {
            "code": "418067008",
            "description": "BETAHISTINE",
            "attributes": null
          },
          {
            "code": "55452001",
            "description": "OXYCODONE",
            "attributes": null
          }
        ]
      }
    ],
    "status": 1,
    "doi": "https://doi.org/10.48533/swwm-rj23",
    "is_deleted": false,
    "publish_status": 2,
    "owner": "Zhuoyu.Li",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 9624,
        "version_name": "Falls Risk Increasing Drugs (FRIDs)",
        "version_date": "2026-07-10T11:50:02.394052Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]