{
  "id": 29356,
  "label": "ischemic stroke",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:1060198",
  "properties": {
    "xrefs": [
      "DOID:0051062",
      "MEDGEN:215292",
      "UMLS:C0948008"
    ],
    "synonyms": [
      "ischaemic stroke"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A stroke disorder caused by obstruction of blood flow to the brain, due to thrombotic (local blood clot formation) or embolic (due to a blood clot or other material traveling from another site) event."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 6825,
      "label": "stroke disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12183
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0051061",
          "EFO:0000712",
          "HP:0001297",
          "MEDGEN:52522",
          "MESH:D020521",
          "NCIT:C3390",
          "SCTID:230690007",
          "UMLS:C0038454",
          "birnlex:12783"
        ],
        "synonyms": [
          "CVA",
          "CVA, cerebrovascular accident",
          "cerebrovascular accident",
          "cerebrovascular accident, (CVA)",
          "stroke",
          "stroke syndrome",
          "syndrome, stroke",
          "undetermined stroke",
          "cerebral infarction"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A sudden loss of neurological function secondary to hemorrhage or ischemia in the brain parenchyma due to a vascular event."
      },
      "child_count": 4,
      "reference_id": "MONDO:0005098"
    }
  ],
  "children": [
    {
      "id": 4726,
      "label": "cerebral infarction",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7072,
        29356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3526",
          "ICD10CM:I63",
          "ICD10CM:I63.9",
          "ICD10WHO:I63",
          "ICD9:433.01",
          "ICD9:433.21",
          "ICD9:433.31",
          "ICD9:433.81",
          "ICD9:434.91",
          "MEDGEN:3321",
          "MESH:D002544",
          "NCIT:C50486",
          "SCTID:432504007",
          "UMLS:C0007785",
          "icd11.foundation:1614716959",
          "icd11.foundation:636274910"
        ],
        "synonyms": [
          "CVA - cerebral infarction",
          "brain infarction of telencephalon",
          "cerebral infarct",
          "cerebral infarction",
          "cerebral ischemia",
          "cerebral, infarction",
          "infarction, cerebral",
          "telencephalon brain infarction"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An ischemic condition of the brain, producing a persistent focal neurological deficit in the area of distribution of the cerebral arteries."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002679"
    },
    {
      "id": 6964,
      "label": "transient ischemic attack",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6993,
        29356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:224",
          "EFO:0003764",
          "HP:0002326",
          "ICD9:435",
          "ICD9:435.8",
          "ICD9:435.9",
          "MEDGEN:853",
          "MESH:D002546",
          "NCIT:C50781",
          "SCTID:266257000",
          "UMLS:C0007787",
          "icd11.foundation:826335789"
        ],
        "synonyms": [
          "TIA",
          "TIA - transient ischemic attack",
          "attack, transient ischaemic",
          "attack, transient ischemic",
          "ischaemic attack, transient",
          "ischemic attack, transient",
          "transient cerebral ischemia (disorder) [ambiguous]",
          "transient ischaemic attack (disease)",
          "transient ischaemic attacks",
          "transient ischemic attack",
          "transient ischemic attack (disease)",
          "transient ischemic attacks",
          "transient cerebral ischemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005264"
    },
    {
      "id": 8153,
      "label": "brain stem infarction",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7072,
        29356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3523",
          "EFO:1000847",
          "ICD9:434.91",
          "MEDGEN:101068",
          "MESH:D020526",
          "SCTID:95457000",
          "UMLS:C0521542"
        ],
        "synonyms": [
          "brain infarction of brainstem",
          "brainstem brain infarction"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Infarctions that occur in the brain stem which is comprised of the midbrain; pons; and medulla oblongata. There are several named syndromes characterized by their distinctive clinical manifestations and specific sites of ischemic injury."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006686"
    },
    {
      "id": 8257,
      "label": "intracranial embolism",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        29356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4372",
          "EFO:1000991",
          "ICD9:434.1",
          "ICD9:434.10",
          "MEDGEN:155710",
          "MESH:D020766",
          "SCTID:75543006",
          "UMLS:C0752140",
          "icd11.foundation:816982857"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Blocking of a blood vessel in the skull by an embolus which can be a blood clot (thrombus) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with heart diseases. Other non-cardiac sources of emboli are usually associated with vascular diseases."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006809"
    },
    {
      "id": 18588,
      "label": "pediatric arterial ischemic stroke",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2933,
        6993,
        29356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021824",
          "MEDGEN:1803840",
          "Orphanet:439175",
          "SCTID:1197363004",
          "UMLS:C5680049"
        ],
        "synonyms": [
          "childhood AIS",
          "childhood arterial ischaemic stroke",
          "childhood arterial ischemic stroke",
          "paediatric AIS",
          "pediatric AIS"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare ischemic disease characterized by focal cerebral ischemia and infarction due to blockage of a brain artery with subsequent impairment of blood supply and oxygenation of brain tissue."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018585"
    }
  ],
  "roots": [
    {
      "id": 6825,
      "label": "stroke disorder"
    }
  ]
}