{
  "id": 24201,
  "label": "severe ichthyosis vulgaris",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100475",
  "properties": {
    "xrefs": [
      "GARD:0026236"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "An instance of ichthyosis vulgaris in which the disease presentation is severe in severity. Homozygous FLG mutation carriers often have more severe manifestations."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 9152,
      "label": "autosomal dominant ichthyosis vulgaris",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2903,
        21337
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1702",
          "GARD:0027780",
          "ICD10CM:Q80.0",
          "MEDGEN:609440",
          "OMIM:146700",
          "Orphanet:462",
          "SCTID:254157005",
          "UMLS:C0432300"
        ],
        "synonyms": [
          "autosomal dominant ichthyosis vulgaris",
          "ichthyosis vulgaris, autosomal dominant",
          "dominant ichthyosis vulgaris",
          "ichthyosis simplex",
          "ichthyosis vulgaris"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Ichthyosis vulgaris is a common skin disorder passed down through families that leads to dry, scaly skin. It often begins in early childhood. Treatment may include heavy duty moisturizers which contain chemicals that help the skin to shed normally, including lactic acid, salicylic acid, and urea. Ichthyosis vulgaris can be a nuisance, but it rarely affects overall health. The condition usually disappears during adulthood, but may return in later years. This condition is inherited in an autosomal dominant pattern."
      },
      "child_count": 4,
      "reference_id": "MONDO:0007810"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 9152,
      "label": "autosomal dominant ichthyosis vulgaris"
    }
  ]
}