{
  "id": 22960,
  "label": "thecoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0037252",
  "properties": {
    "xrefs": [
      "ICDO:8600/0",
      "MEDGEN:21505",
      "MESH:D013798",
      "NCIT:C3405",
      "UMLS:C0039747"
    ],
    "synonyms": [
      "thecoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "An ovarian or testicular stromal tumor characterized by the presence of lipid-rich neoplastic spindle cells. In females, uterine bleeding is the most common symptom. A minority of post-menopausal women with thecoma have an associated endometrial adenocarcinoma or rarely a malignant mixed mullerian tumor or endometrial stromal sarcoma. Rare cases with nuclear atypia and mitotic activity may metastasize. In males, thecomas are rare and they usually present as slow growing, sometimes painful masses. Metastases have not been reported."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7639,
      "label": "sex cord-stromal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7638
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:192",
          "EFO:1000052",
          "ICDO:8590/1",
          "MEDGEN:104926",
          "NANDO:2200072",
          "NCIT:C3794",
          "UMLS:C0206724"
        ],
        "synonyms": [
          "Sex cord stromal tumor",
          "Sex cord-stromal neoplasm",
          "Sex cord-stromal tumor",
          "Sex cord-stromal tumor, no ICD-O subtype",
          "Sex cord-stromal tumor, no ICD-O subtype (morphologic abnormality)",
          "Sex cord-stromal tumour",
          "neoplasm of sex cord",
          "sex cord neoplasm",
          "sex cord tumor",
          "sex cord tumour",
          "sex cord-stromal tumor",
          "specialised gonadal neoplasm",
          "specialised gonadal neoplasm (morphologic abnormality)",
          "specialised gonadal neoplasm NOS (morphologic abnormality)",
          "specialised gonadal tumour",
          "specialised gonadal tumour (qualifier value)",
          "specialized gonadal neoplasm (morphologic abnormality)",
          "specialized gonadal neoplasm NOS (morphologic abnormality)",
          "specialized gonadal tumor (qualifier value)",
          "tumor of sex cord",
          "tumour of sex cord",
          "malignant testicular sex cord-stromal tumor",
          "malignant testicular sex cord-stromal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A neoplasm involving a sex cord."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006055"
    }
  ],
  "children": [
    {
      "id": 6141,
      "label": "testicular thecoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5102,
        22960
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7676",
          "GARD:0023937",
          "MEDGEN:308260",
          "NCIT:C39952",
          "UMLS:C1515299"
        ],
        "synonyms": [
          "testis thecoma",
          "thecoma of testis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare benign tumor that arises from the testis and is characterized by the presence of lipid-rich neoplastic spindle cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004325"
    },
    {
      "id": 22961,
      "label": "ovarian thecoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20709,
        22960
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027955",
          "MEDGEN:364155",
          "NCIT:C66989",
          "SCTID:254864005",
          "UMLS:C1882229"
        ],
        "synonyms": [
          "ovarian theca cell neoplasm",
          "ovarian theca cell tumor",
          "ovarian theca cell tumour",
          "ovarian thecoma",
          "ovary thecoma",
          "theca cell neoplasm of ovary",
          "theca cell neoplasm of the ovary",
          "theca cell tumor of ovary",
          "theca cell tumor of the ovary",
          "theca cell tumour of ovary",
          "theca cell tumour of the ovary",
          "thecoma of ovary",
          "thecoma of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A stromal tumor that arises from the ovary and is characterized by the presence of cells that contain lipid and resemble theca cells. The vast majority of cases are benign."
      },
      "child_count": 0,
      "reference_id": "MONDO:0037253"
    }
  ],
  "roots": [
    {
      "id": 7639,
      "label": "sex cord-stromal tumor"
    }
  ]
}