{
  "id": 21337,
  "label": "ichthyosis vulgaris",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024304",
  "properties": {
    "xrefs": [
      "GARD:0006752",
      "MEDGEN:38217",
      "MESH:D016112",
      "NCIT:C84778",
      "UMLS:C0079584",
      "icd11.foundation:841161884"
    ],
    "synonyms": [
      "ichthyosis vulgaris",
      "common ichthyosis",
      "fish scale disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "The most common form of ichthyosis. It is an autosomal dominant inherited or acquired disorder characterized by scaling and desquamation of the skin."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 16624,
      "label": "inherited ichthyosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19130,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020261",
          "ICD10CM:Q80",
          "ICD9:757.1",
          "MEDGEN:797407",
          "MedDRA:10021202",
          "NANDO:1200609",
          "NANDO:2100283",
          "Orphanet:183435",
          "SCTID:13059002",
          "UMLS:C0856562"
        ],
        "synonyms": [
          "congenital ichthyosis of skin",
          "genetic ichthyosis",
          "hereditary ichthyosis (disease)",
          "inherited genetic ichthyosis",
          "congenital ichthyosis",
          "fish scale disease",
          "fish skin",
          "ichthyosis congenita"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Mendelian disorders of cornification affecting all or most of integument characterized by hyperkeratosis and/or scaling, caused by an inherited modification of the individual's genome."
      },
      "child_count": 26,
      "reference_id": "MONDO:0015947"
    }
  ],
  "children": [
    {
      "id": 9152,
      "label": "autosomal dominant ichthyosis vulgaris",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2903,
        21337
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1702",
          "GARD:0027780",
          "ICD10CM:Q80.0",
          "MEDGEN:609440",
          "OMIM:146700",
          "Orphanet:462",
          "SCTID:254157005",
          "UMLS:C0432300"
        ],
        "synonyms": [
          "autosomal dominant ichthyosis vulgaris",
          "ichthyosis vulgaris, autosomal dominant",
          "dominant ichthyosis vulgaris",
          "ichthyosis simplex",
          "ichthyosis vulgaris"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Ichthyosis vulgaris is a common skin disorder passed down through families that leads to dry, scaly skin. It often begins in early childhood. Treatment may include heavy duty moisturizers which contain chemicals that help the skin to shed normally, including lactic acid, salicylic acid, and urea. Ichthyosis vulgaris can be a nuisance, but it rarely affects overall health. The condition usually disappears during adulthood, but may return in later years. This condition is inherited in an autosomal dominant pattern."
      },
      "child_count": 4,
      "reference_id": "MONDO:0007810"
    }
  ],
  "roots": [
    {
      "id": 16624,
      "label": "inherited ichthyosis"
    }
  ]
}