{
  "id": 21291,
  "label": "Brenner tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024235",
  "properties": {
    "xrefs": [
      "ICDO:9000/0",
      "MEDGEN:2345",
      "MESH:D001948",
      "NCIT:C39954",
      "ONCOTREE:BTOV",
      "UMLS:C0006160"
    ],
    "synonyms": [
      "Brenner tumor"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A usually benign tumor composed of solid and cystic nests of epithelial cells resembling transitional epithelium; it is surrounded by an abundant stromal component that is dense and fibroblastic in nature."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7638,
      "label": "reproductive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6772,
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000051",
          "MEDGEN:64246",
          "NCIT:C3674",
          "UMLS:C0178830"
        ],
        "synonyms": [
          "neoplasm of reproductive system",
          "neoplasm of the reproductive system",
          "reproductive neoplasm",
          "reproductive system neoplasm",
          "reproductive system neoplasm (disease)",
          "reproductive system tumor",
          "reproductive system tumour",
          "reproductive tumor",
          "reproductive tumour",
          "tumor of reproductive system",
          "tumor of the reproductive system",
          "tumour of reproductive system",
          "tumour of the reproductive system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm affecting the male and female reproductive system."
      },
      "child_count": 18,
      "reference_id": "MONDO:0006054"
    },
    {
      "id": 22962,
      "label": "transitional cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:90754",
          "NCIT:C6783",
          "UMLS:C0334265"
        ],
        "synonyms": [
          "transitional cell neoplasm",
          "transitional cell tumor",
          "transitional cell tumour"
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0037254"
    }
  ],
  "children": [
    {
      "id": 4468,
      "label": "ovarian Brenner tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4347,
        21291
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2636",
          "GARD:0009397",
          "MEDGEN:1716777",
          "NCIT:C3872",
          "SCTID:254859006",
          "UMLS:C5234884"
        ],
        "synonyms": [
          "Brenner tumor",
          "Brenner tumour",
          "Brenner neoplasm of ovary",
          "Brenner neoplasm of the ovary",
          "Brenner tumor of ovary",
          "Brenner tumor of the ovary",
          "Brenner tumour of ovary",
          "Brenner tumour of the ovary",
          "ovarian Brenner neoplasm",
          "ovarian Brenner tumor",
          "ovary Brenner tumor",
          "ovary Brenner tumour",
          "benign ovarian Brenner tumor",
          "benign ovarian Brenner tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant transitional cell neoplasm arising from the ovary. It constitutes between 1% and 2% of all ovarian neoplasms. The average age at presentation is about 50 years. Grossly it is usually unilateral, firm and white or yellowish. Microscopically it consists of solid and cystic nests of epithelial cells resembling transitional epithelium surrounded by an abundant stromal component of dense, fibroblastic nature."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002370"
    },
    {
      "id": 5097,
      "label": "testicular Brenner tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20517,
        21291
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4739",
          "MEDGEN:273631",
          "NCIT:C39953",
          "UMLS:C1515281"
        ],
        "synonyms": [
          "testes, rudimentary Brenner tumor",
          "testes, rudimentary Brenner tumour",
          "testis Brenner tumor",
          "testis Brenner tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An uncommon usually benign neoplasm that arises from the testis. It is characterized by the presence of cysts lined by transitional cells and solid nests of transitional cells in a spindle cell stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003118"
    },
    {
      "id": 20906,
      "label": "extraovarian Brenner tumor of the vagina",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20294,
        21291
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "extraovarian Brenner tumor of the vagina",
          "vagina Brenner tumor",
          "vagina Brenner tumour",
          "Brenner tumor of the vagina",
          "Brenner tumour of the vagina"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A Brenner tumor that involves the vagina."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022607"
    }
  ],
  "roots": [
    {
      "id": 7638,
      "label": "reproductive system neoplasm"
    },
    {
      "id": 22962,
      "label": "transitional cell neoplasm"
    }
  ]
}