{
  "id": 20384,
  "label": "female reproductive system neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021148",
  "properties": {
    "xrefs": [
      "MEDGEN:9004",
      "MESH:D005833",
      "NCIT:C3053",
      "UMLS:C0017416"
    ],
    "synonyms": [
      "female reproductive organ neoplasm (disease)",
      "female reproductive organ tumor",
      "female reproductive organ tumour",
      "female reproductive system neoplasm",
      "female reproductive system neoplasm (disease)",
      "female reproductive system tumor",
      "female reproductive system tumour",
      "gynecologic neoplasm",
      "gynecologic tumor",
      "gynecologic tumour",
      "neoplasm of female reproductive organ",
      "neoplasm of female reproductive system",
      "neoplasm of the female reproductive system",
      "tumor of female reproductive system",
      "tumor of the female reproductive system",
      "tumour of female reproductive system",
      "tumour of the female reproductive system"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A benign, precancerous, or malignant neoplasm that affects the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, ovarian carcinoma, cervical carcinoma, and endometrial carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 11,
  "parents": [
    {
      "id": 4379,
      "label": "female reproductive system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6772
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:229",
          "EFO:0009549",
          "ICD9:629.9",
          "MEDGEN:65928",
          "MESH:D005831",
          "NCIT:C27020",
          "SCTID:310789003",
          "UMLS:C0236100"
        ],
        "synonyms": [
          "disease of female reproductive system",
          "disease or disorder of female reproductive system",
          "disorder of female genital system",
          "disorder of female reproductive system",
          "female reproductive disease",
          "female reproductive system disease",
          "female reproductive system disease or disorder",
          "female reproductive system disorder",
          "disease of female genital system",
          "disorder of female genital tract",
          "gynaecological disease",
          "gynecological disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A disease involving the female reproductive system."
      },
      "child_count": 34,
      "reference_id": "MONDO:0002263"
    },
    {
      "id": 7638,
      "label": "reproductive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6772,
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000051",
          "MEDGEN:64246",
          "NCIT:C3674",
          "UMLS:C0178830"
        ],
        "synonyms": [
          "neoplasm of reproductive system",
          "neoplasm of the reproductive system",
          "reproductive neoplasm",
          "reproductive system neoplasm",
          "reproductive system neoplasm (disease)",
          "reproductive system tumor",
          "reproductive system tumour",
          "reproductive tumor",
          "reproductive tumour",
          "tumor of reproductive system",
          "tumor of the reproductive system",
          "tumour of reproductive system",
          "tumour of the reproductive system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm affecting the male and female reproductive system."
      },
      "child_count": 18,
      "reference_id": "MONDO:0006054"
    }
  ],
  "children": [
    {
      "id": 3029,
      "label": "benign female reproductive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2882,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060086",
          "MEDGEN:152872",
          "NCIT:C4934",
          "UMLS:C0744514"
        ],
        "synonyms": [
          "benign female reproductive system neoplasm",
          "benign female reproductive system tumor",
          "benign female reproductive system tumour",
          "benign gynecologic neoplasm",
          "benign gynecologic tumor",
          "benign gynecologic tumour",
          "female reproductive organ benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm that arises from the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, and benign ovarian germ cell tumor."
      },
      "child_count": 14,
      "reference_id": "MONDO:0000624"
    },
    {
      "id": 3637,
      "label": "female reproductive organ cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4279,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:120",
          "EFO:1001331",
          "ICD10CM:C51-C58",
          "ICD9:184",
          "MEDGEN:195944",
          "NCIT:C4913",
          "SCTID:126907002",
          "UMLS:C0699889"
        ],
        "synonyms": [
          "cancer of female reproductive organ",
          "female reproductive cancer",
          "female reproductive organ cancer",
          "gynecologic cancer",
          "malignant female reproductive organ neoplasm",
          "malignant female reproductive system neoplasm",
          "malignant female reproductive system tumor",
          "malignant female reproductive system tumour",
          "malignant gynecologic neoplasm",
          "malignant gynecologic tumor",
          "malignant gynecologic tumour",
          "malignant neoplasm of female reproductive organ",
          "malignant neoplasm of female reproductive system",
          "malignant neoplasm of the female reproductive system",
          "malignant tumor of female reproductive system",
          "malignant tumor of the female reproductive system",
          "malignant tumour of female reproductive system",
          "malignant tumour of the female reproductive system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the female reproductive system. Representative examples include endometrial carcinoma, cervical carcinoma, ovarian carcinoma, uterine corpus leiomyosarcoma, adenosarcoma, malignant mixed mesodermal (mullerian) tumor, and gestational choriocarcinoma."
      },
      "child_count": 18,
      "reference_id": "MONDO:0001416"
    },
    {
      "id": 4560,
      "label": "endometrioid tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3001",
          "MEDGEN:105374",
          "NCIT:C7113",
          "UMLS:C0474809"
        ],
        "synonyms": [
          "endometrioid neoplasm",
          "endometrioid neoplasm of female reproductive system",
          "endometrioid neoplasm of the female reproductive system",
          "endometrioid tumor",
          "endometrioid tumor (morphologic abnormality)",
          "endometrioid tumor of female reproductive system",
          "endometrioid tumor of the female reproductive system",
          "endometrioid tumour (morphologic abnormality)",
          "endometrioid tumour of female reproductive system",
          "endometrioid tumour of the female reproductive system",
          "female reproductive endometrioid neoplasm",
          "female reproductive endometrioid tumor",
          "female reproductive endometrioid tumour",
          "female reproductive endometrioid cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant epithelial tumor of the female reproductive system characterized by the presence of glands and/or cysts lined by neoplastic cells that resemble endometrial cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002480"
    },
    {
      "id": 5024,
      "label": "endometrioid stromal and related neoplasms of the cervix",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4521",
          "MEDGEN:927118",
          "NCIT:C40218",
          "UMLS:C4289586"
        ],
        "synonyms": [
          "endometrioid stromal and related neoplasms of the cervix",
          "endometrioid stromal and related tumors of the cervix",
          "endometrioid stromal and related tumours of the cervix",
          "cervix endometrial stromal tumor",
          "cervix endometrial stromal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A category of rare neoplasms that arise from the cervix. It includes low grade endometrioid stromal sarcoma and undifferentiated endocervical sarcoma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0003031"
    },
    {
      "id": 18866,
      "label": "gestational trophoblastic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4886,
        20384,
        21520
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3590",
          "GARD:0006498",
          "ICD9:630",
          "MEDGEN:210107",
          "MedDRA:10061988",
          "NCIT:C4699",
          "Orphanet:59305",
          "SCTID:609519004",
          "UMLS:C1135868",
          "icd11.foundation:1972855304"
        ],
        "synonyms": [
          "gestational trophoblastic disease",
          "GTN",
          "GTT",
          "gestational trophoblastic tumor",
          "gestational trophoblastic tumour",
          "hydatidiform mole",
          "molar pregnancy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A diverse group of pregnancy-related tumors characterized by excessive proliferation of trophoblasts. Representative examples include hydatidiform mole, gestational choriocarcinoma, and placental site trophoblastic tumor."
      },
      "child_count": 18,
      "reference_id": "MONDO:0018944"
    },
    {
      "id": 20293,
      "label": "vulvar neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4310,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:239.5",
          "MEDGEN:22689",
          "NCIT:C3443",
          "SCTID:126922007",
          "UMLS:C0042995"
        ],
        "synonyms": [
          "mammalian vulva neoplasm",
          "mammalian vulva neoplasm (disease)",
          "mammalian vulva tumor",
          "mammalian vulva tumour",
          "neoplasm of mammalian vulva",
          "neoplasm of the vulva",
          "neoplasm of vulva",
          "tumor of mammalian vulva",
          "tumor of the vulva",
          "tumor of vulva",
          "tumour of mammalian vulva",
          "tumour of the vulva",
          "tumour of vulva",
          "vulva neoplasm",
          "vulva tumor",
          "vulva tumour",
          "vulval neoplasm",
          "vulvar neoplasm",
          "vulvar tumor",
          "vulvar tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the vulva. Representative examples include Bartholin gland adenoma, vulvar nodular hidradenoma, vulvar carcinoma, and vulvar melanoma."
      },
      "child_count": 18,
      "reference_id": "MONDO:0021049"
    },
    {
      "id": 20294,
      "label": "vaginal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3651,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001447",
          "ICD9:239.5",
          "MEDGEN:22608",
          "NCIT:C3437",
          "ONCOTREE:VULVA",
          "SCTID:126921000",
          "UMLS:C0042258"
        ],
        "synonyms": [
          "neoplasm of the vagina",
          "neoplasm of vagina",
          "tumor of the vagina",
          "tumor of vagina",
          "tumour of the vagina",
          "tumour of vagina",
          "vagina neoplasm",
          "vagina neoplasm (disease)",
          "vagina tumor",
          "vagina tumour",
          "vaginal neoplasm",
          "vaginal tumor",
          "vaginal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the vagina. Representative examples of benign neoplasms include squamous papilloma and melanocytic nevus. Representative examples of malignant neoplasms include carcinoma, melanoma, and sarcoma."
      },
      "child_count": 14,
      "reference_id": "MONDO:0021050"
    },
    {
      "id": 20309,
      "label": "ovarian neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7207,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003893",
          "ICD9:239.5",
          "MEDGEN:181539",
          "NCIT:C4984",
          "SCTID:123843001",
          "UMLS:C0919267"
        ],
        "synonyms": [
          "neoplasm of ovary",
          "neoplasm of the ovary",
          "ovarian neoplasm",
          "ovarian tumor",
          "ovarian tumors",
          "ovarian tumour",
          "ovarian tumours",
          "ovary neoplasm",
          "ovary neoplasm (disease)",
          "ovary tumor",
          "ovary tumour",
          "tumor of ovary",
          "tumor of the ovary",
          "tumour of ovary",
          "tumour of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant neoplasm involving the ovary."
      },
      "child_count": 16,
      "reference_id": "MONDO:0021068"
    },
    {
      "id": 20332,
      "label": "fallopian tube neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4285,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:239.5",
          "MEDGEN:8775",
          "MESH:D005185",
          "NCIT:C3032",
          "SCTID:126916003",
          "UMLS:C0015558"
        ],
        "synonyms": [
          "fallopian tube neoplasm",
          "fallopian tube neoplasm (disease)",
          "fallopian tube tumor",
          "fallopian tube tumour",
          "neoplasm of fallopian tube",
          "neoplasm of the fallopian tube",
          "tumor of fallopian tube",
          "tumor of the fallopian tube",
          "tumour of fallopian tube",
          "tumour of the fallopian tube"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the fallopian tube. Representative examples of benign neoplasms include papilloma, adenofibroma, and leiomyoma. Representative examples of malignant neoplasms include carcinoma, carcinosarcoma, and adenosarcoma."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021092"
    },
    {
      "id": 20520,
      "label": "tumor of uterus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4705,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003859",
          "ICD9:239.5",
          "MEDGEN:12030",
          "NCIT:C3435",
          "ONCOTREE:UTERUS",
          "SCTID:126908007",
          "UMLS:C0042138"
        ],
        "synonyms": [
          "neoplasm of the uterus",
          "neoplasm of uterus",
          "tumor of the uterus",
          "tumor of uterus",
          "tumour of the uterus",
          "uterine neoplasm",
          "uterine neoplasms",
          "uterine tumor",
          "uterine tumour",
          "uterus neoplasm",
          "uterus neoplasm (disease)",
          "uterus tumor",
          "uterus tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the uterus."
      },
      "child_count": 12,
      "reference_id": "MONDO:0021353"
    },
    {
      "id": 22972,
      "label": "endometrioid stromal and related neoplasms",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:925400",
          "NCIT:C8384",
          "UMLS:C4287868"
        ],
        "synonyms": [
          "endometrioid stromal and related neoplasms",
          "endometrioid stromal and related tumors",
          "endometrioid stromal and related tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A category of mesenchymal gynecologic neoplasms. It includes endometrial stromal nodule, endometrioid stromal sarcoma, and undifferentiated sarcoma. Endometrial stromal nodule has been described in the uterine corpus only. Histologically, it is characterized by the lack of infiltration of the surrounding tissues. Endometrioid stromal sarcoma affects the uterine corpus, and rarely, the ovaries, cervix, and vagina. In the uterine corpus it is classified as low grade or high grade endometrial stromal sarcoma. In the remainder of the anatomic sites it is classified as low grade endometrioid stromal sarcoma. Undifferentiated sarcoma was previously also known as high grade endometrial stromal sarcoma. In 2014, high grade endometrial stromal sarcoma was reclassified and is currently considered a distinct and rare neoplasm that affects the uterine corpus only. It appears to have a prognosis that falls between low grade endometrial stromal sarcoma and undifferentiated sarcoma. The latter affects the uterine corpus and rarely the remainder of the anatomic sites."
      },
      "child_count": 2,
      "reference_id": "MONDO:0037742"
    }
  ],
  "roots": [
    {
      "id": 4379,
      "label": "female reproductive system disorder"
    },
    {
      "id": 7638,
      "label": "reproductive system neoplasm"
    }
  ]
}