{
  "id": 20376,
  "label": "bone marrow cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021138",
  "properties": {
    "xrefs": [
      "GARD:0025293",
      "MEDGEN:438070",
      "NCIT:C35501",
      "UMLS:C2703042"
    ],
    "synonyms": [
      "bone marrow cancer",
      "cancer of bone marrow",
      "malignant bone marrow neoplasm",
      "malignant bone marrow tumor",
      "malignant bone marrow tumour",
      "malignant neoplasm of bone marrow"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Malignant neoplasms that either originate from the bone marrow (e.g. myeloid leukemias) or involve the bone marrow as secondary-metastatic tumors (e.g. metastatic carcinomas to the bone marrow). --2003"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 3028,
      "label": "immune system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        6778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060083"
        ],
        "synonyms": [
          "cancer of immune system",
          "immune system cancer",
          "malignant immune system neoplasm",
          "malignant neoplasm of immune system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the immune system"
      },
      "child_count": 50,
      "reference_id": "MONDO:0000621"
    },
    {
      "id": 4262,
      "label": "bone cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3041,
        18958
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2019-1041",
          "DOID:184",
          "EFO:1000350",
          "GARD:0023070",
          "ICD9:170.9",
          "MEDGEN:79002",
          "MESH:D001859",
          "NCIT:C4016",
          "SCTID:428281000",
          "UMLS:C0279530"
        ],
        "synonyms": [
          "bone neoplasm",
          "bone tumor",
          "bone tumour",
          "osseous tumor",
          "osseous tumour",
          "bone cancer",
          "cancer of bone",
          "cancer of skeletal element",
          "cancer of the bone",
          "malignant bone neoplasm",
          "malignant bone tumor",
          "malignant neoplasm of bone",
          "malignant neoplasm of skeletal element",
          "malignant neoplasm of the bone",
          "malignant osseous neoplasm",
          "malignant osseous tumor",
          "malignant osseous tumour",
          "malignant skeletal element neoplasm",
          "malignant tumor of bone",
          "malignant tumor of the bone",
          "malignant tumour of bone",
          "malignant tumour of the bone",
          "osseous cancer",
          "skeletal element cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the bone or articular cartilage."
      },
      "child_count": 24,
      "reference_id": "MONDO:0002129"
    },
    {
      "id": 7055,
      "label": "bone marrow neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440,
        5177
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4960",
          "GARD:0024177",
          "ICD9:238.79",
          "MEDGEN:129203",
          "MESH:D019046",
          "NCIT:C35370",
          "SCTID:414824005",
          "UMLS:C0282609"
        ],
        "synonyms": [
          "bone marrow neoplasm",
          "bone marrow neoplasm (disease)",
          "bone marrow tumor",
          "bone marrow tumour",
          "neoplasm of bone marrow",
          "tumor of bone marrow",
          "tumour of bone marrow",
          "bone marrow cancer",
          "malignant bone marrow tumor",
          "malignant bone marrow tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Neoplasms that affect the bone marrow. Such neoplasms may arise in the bone marrow (e.g. myeloid leukemias) or may involve the bone marrow as secondary, metastatic tumors (e.g. metastatic carcinomas to the bone marrow)."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005374"
    }
  ],
  "children": [
    {
      "id": 19727,
      "label": "myeloproliferative neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6892,
        16513,
        20376
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2226",
          "EFO:0002428",
          "GARD:0009319",
          "ICD9:238.79",
          "ICDO:9960/3",
          "ICDO:9975/1",
          "MEDGEN:220955",
          "MedDRA:10028576",
          "NCIT:C4345",
          "ONCOTREE:MPN",
          "Orphanet:98274",
          "SCTID:425333006",
          "UMLS:C1292778"
        ],
        "synonyms": [
          "CMPD",
          "MPD",
          "MPN",
          "chronic myeloproliferative disease",
          "chronic myeloproliferative disorder",
          "chronic myeloproliferative neoplasm",
          "myeloproliferative disorder",
          "myeloproliferative neoplasm",
          "myeloproliferative neoplasm, chronic",
          "myeloproliferative tumor",
          "myeloproliferative tumour",
          "CMPD, U",
          "chronic myeloproliferative disorders",
          "myeloproliferative neoplasms"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)"
      },
      "child_count": 39,
      "reference_id": "MONDO:0020076"
    }
  ],
  "roots": [
    {
      "id": 3028,
      "label": "immune system cancer"
    },
    {
      "id": 4262,
      "label": "bone cancer"
    },
    {
      "id": 7055,
      "label": "bone marrow neoplasm"
    }
  ]
}