{
  "id": 19165,
  "label": "pemphigus foliaceus",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019324",
  "properties": {
    "xrefs": [
      "DOID:0080850",
      "EFO:0008601",
      "GARD:0007354",
      "HGNC:3050",
      "MEDGEN:75513",
      "MedDRA:10057069",
      "NANDO:1200230",
      "Orphanet:79481",
      "SCTID:35154004",
      "UMLS:C0263313",
      "icd11.foundation:24246260"
    ],
    "synonyms": [
      "PF"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Pemphigus foliaceous is a rare superficial pemphigus disease characterized by multiple, pruritic, scaly, crusted cutaneous erosions, with flaky circumscribed patches, localized mostly on the face, scalp, trunk and extremities, often presenting an erythematous base. Mucosal involvement is rarely observed."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 8070,
      "label": "pemphigus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19177
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9182",
          "EFO:1000749",
          "GARD:0007352",
          "ICD10CM:L10",
          "ICD10WHO:L10",
          "ICD9:694.4",
          "MEDGEN:45369",
          "MESH:D010392",
          "NANDO:1200228",
          "NCIT:C34909",
          "SCTID:65172003",
          "UMLS:C0030807",
          "Wikipedia:Pemphigus",
          "icd11.foundation:191659986"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Pemphigus is a group of rare autoimmune diseases that cause blistering of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals).This conditioncan occur at any age, but often strikes people in middle or older age. Studies have shown that some populations may be at greater risk for certain types of pemphigus. For instance, people of Jewish descent and those from India, Southeast Europe, and the Middle East are at greater risk for pemphigus vulargis, while pemphigus foliaceus is more common in North America, Turkey, and South America. Pemphigus is a chronic disease which is best controlled by early diagnosis and treatment.Treatment includes steroids to reduce inflammation,drugs that suppress the immune system responseand antibiotics to treat associated infections. There are four main types of pemphigus: Pemphigus vulgaris Pemphigus foliaceus IgA pemphigus Paraneoplastic pemphigus"
      },
      "child_count": 6,
      "reference_id": "MONDO:0006594"
    }
  ],
  "children": [
    {
      "id": 23177,
      "label": "pemphigus and fogo selvagem",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007353",
          "HGNC:3048",
          "MEDGEN:120470",
          "MESH:C535551",
          "Orphanet:636955",
          "SCTID:46459009",
          "UMLS:C0263314"
        ],
        "synonyms": [
          "Brazilian pemphigus foliaceus",
          "Brazilian pemphigus",
          "FS",
          "South American pemphigus",
          "amendola's syndrome",
          "endemic pemphigus foliaceus",
          "fogo selvagem",
          "wild fire",
          "wildfire pemphigus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0043257"
    }
  ],
  "roots": [
    {
      "id": 8070,
      "label": "pemphigus"
    }
  ]
}