{
  "id": 18357,
  "label": "hypocomplementemic urticarial vasculitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018227",
  "properties": {
    "xrefs": [
      "GARD:0006725",
      "MEDGEN:83360",
      "Orphanet:36412",
      "SCTID:239945009",
      "UMLS:C0343206",
      "icd11.foundation:629572966"
    ],
    "synonyms": [
      "Mac Duffie hypocomplementemic urticarial vasculitis",
      "Mac Duffie syndrome",
      "McDuffie hypocomplementemic urticarial vasculitis",
      "McDuffie syndrome",
      "anti-C1q vasculitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Hypocomplementemic urticarial vasculitis (HUV) is an immune complex-mediated small vessel vasculitis characterized by urticaria and hypocomplementemia (low C1q with or without low C3 and C4), and usually associated with circulating anti-C1q autoantibodies. Arthritis, pulmonary disease, ocular inflammation, and glomerulonephritis are common systemic manifestations."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16323,
      "label": "immune complex mediated vasculitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18813
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019984",
          "MEDGEN:1842565",
          "Orphanet:156149",
          "UMLS:C5680655"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0015491"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16323,
      "label": "immune complex mediated vasculitis"
    }
  ]
}