{
  "id": 17156,
  "label": "pilomyxoid astrocytoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016692",
  "properties": {
    "xrefs": [
      "DOID:4845",
      "GARD:0020710",
      "ICDO:9425/3",
      "MEDGEN:276757",
      "NCIT:C40315",
      "ONCOTREE:PMA",
      "Orphanet:251615",
      "UMLS:C1519086"
    ],
    "synonyms": [
      "PMA"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An astrocytic tumor of uncertain relation to pilocytic astrocytoma. It occurs predominantly in infants and young children. It is characterized by a monomorphic architectural pattern, usually associated with the absence of Rosenthal fibers and eosinophilic granular bodies. The clinical course is usually aggressive."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17155,
      "label": "pilocytic astrocytoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17149
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4851",
          "GARD:0009808",
          "ICDO:9421/1",
          "MEDGEN:87271",
          "NANDO:2200084",
          "NCIT:C4047",
          "ONCOTREE:PAST",
          "Orphanet:251612",
          "SCTID:763865009",
          "UMLS:C0334583"
        ],
        "synonyms": [
          "astrocytoma, benign",
          "astrocytoma, pilocytic, benign",
          "grade I astrocytic neoplasm",
          "grade I astrocytic tumor",
          "grade I astrocytic tumour",
          "grade I astrocytoma",
          "pilocytic astrocytoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Pilocytic astrocytoma is a rare subtype of low-grade glioma of the central nervous system characterized by a well circumscribed, often cystic, brain tumor with a discrete mural nodule and long, hair-like projections that extend from the neoplastic astrocytes. Depending on the primary localization and the size of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), blurred vision, decreased visual acuity, ataxia and/or nystagmus, among others. It is most commonly located in the cerebellum, but occurrence in the hypothalamus, brain stem, optic chiasma, and hemispheres has also been reported."
      },
      "child_count": 4,
      "reference_id": "MONDO:0016691"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17155,
      "label": "pilocytic astrocytoma"
    }
  ]
}