{
  "id": 16140,
  "label": "schistosomiasis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015254",
  "properties": {
    "xrefs": [
      "DOID:1395",
      "EFO:1001475",
      "GARD:0009687",
      "ICD10CM:B65",
      "ICD9:120.8",
      "ICD9:120.9",
      "MEDGEN:48573",
      "MESH:D012552",
      "MedDRA:10039603",
      "NCIT:C35000",
      "Orphanet:1247",
      "SCTID:10087007",
      "UMLS:C0036323",
      "icd11.foundation:1194562592"
    ],
    "synonyms": [
      "Bilharzia",
      "bilharziasis",
      "schistosomiasis",
      "snail fever"
    ],
    "definition": "An infectious disease caused by parasitic trematodes of the genus Schistosoma that colonize human blood vessels and release eggs that can cause granulomatous reactions leading to acute (swimmer's itch or acute schistosomiasis syndrome) or chronic disease. Depending on where the eggs lodge, manifestations of chronic schistosomiasis can include diarrhea, abdominal pain, loss of appetite, anemia (intestines), hepatosplenism, periportal fibrosis with portal hypertension (liver), urogenital inflammation and scarring, hematuria and dysuria (genitourinary system). Other patients may be asymptomatic."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 6448,
      "label": "helminthiasis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6859
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:883",
          "EFO:1001342",
          "ICD10CM:B65-B83",
          "ICD9:120-129",
          "ICD9:128.8",
          "ICD9:128.9",
          "MEDGEN:6765",
          "MESH:D006373",
          "NCIT:C84751",
          "SCTID:27601005",
          "UMLS:C0018889"
        ],
        "synonyms": [
          "helminthiasis",
          "worm infection"
        ],
        "definition": "A parasitic infection characterized by the infestation with worms, mainly in the intestine."
      },
      "child_count": 22,
      "reference_id": "MONDO:0004664"
    },
    {
      "id": 23869,
      "label": "vector-borne disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:738484",
          "MESH:D000079426",
          "UMLS:C1640363"
        ],
        "synonyms": [
          "vector-borne infection",
          "vector-borne infectious disease"
        ],
        "definition": "An infectious disease where a pathogen is carried and transmitted by another organism that acts as disease vector."
      },
      "child_count": 49,
      "reference_id": "MONDO:0100120"
    }
  ],
  "children": [
    {
      "id": 3497,
      "label": "cercarial dermatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16140,
        20419,
        21525
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11302",
          "GARD:0009747",
          "ICD10CM:B65.3",
          "ICD9:120.3",
          "ICD9:709.8",
          "MEDGEN:108186",
          "NCIT:C128349",
          "SCTID:238534006",
          "UMLS:C0546996",
          "icd11.foundation:648519873"
        ],
        "synonyms": [
          "cutaneous schistosomiasis",
          "duck Itch",
          "lake Itch",
          "swimmer's itch"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An unusual presentation of schistosomiasis characterized by a pruritic papular rash in the perigenital or periumbilical area due to an allergic reaction to schistosoma eggs deposited in the skin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001260"
    },
    {
      "id": 7481,
      "label": "neuroschistosomiasis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16140,
        21534
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13722",
          "EFO:0007394",
          "GARD:0024249",
          "MEDGEN:155718",
          "MESH:D020818",
          "UMLS:C0752191",
          "icd11.foundation:446216876"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Schistosomiasis of the brain, spinal cord, or meninges caused by infections with trematodes of the genus schistosoma (primarily schistosoma japonicum; schistosoma mansoni; and schistosoma haematobium in humans). S. japonicum infections of the nervous system may cause an acute meningoencephalitis or a chronic encephalopathy. S. mansoni and S. haematobium nervous system infections are associated with acute transverse myelitis involving the lower portions of the spinal cord. (From Joynt, Clinical Neurology, 1998, Ch27, pp61-2)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0005874"
    },
    {
      "id": 7592,
      "label": "urinary schistosomiasis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7612,
        16140,
        24067
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1394",
          "EFO:0007530",
          "GARD:0024269",
          "ICD10CM:B65.0",
          "ICD9:120.0",
          "MEDGEN:312392",
          "MESH:D012553",
          "NCIT:C39294",
          "SCTID:236706006",
          "UMLS:C1704430"
        ],
        "synonyms": [
          "Schistosoma haematobium (& vesical schistosomiasis)",
          "Schistosoma hematobium infection",
          "schistosomiasis due to Schistosoma haematobium",
          "urinary bladder schistosomiasis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A bladder infection that occurs as a manifetation of a systemic infection with one or more species of the parasitic worms of the Schistosoma type; this can progress to bladder cancer in time."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006001"
    },
    {
      "id": 9709,
      "label": "intestinal schistosomiasis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16140,
        21310
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050597",
          "GARD:0024618",
          "ICD9:120.1",
          "ICD9:120.2",
          "MEDGEN:116602",
          "SCTID:240796008",
          "UMLS:C0242497"
        ],
        "synonyms": [
          "Schistosoma mansoni infection, susceptibility/resistance to",
          "Schistosoma mansoni, intensity of infection by"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An intestinal infection that is caused by Schistosoma japonicum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008412"
    },
    {
      "id": 23344,
      "label": "Schistosoma japonicum infectious disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025900",
          "MESH:D012554",
          "NCIT:C35001",
          "SCTID:268058007"
        ],
        "synonyms": [
          "Schistosoma japonicum caused disease or disorder",
          "Schistosoma japonicum disease or disorder",
          "Schistosoma japonicum infection",
          "Asiatic schistosomiasis",
          "Katamaya fever",
          "Katamaya syndrome",
          "Katayama disease",
          "schistosomiasis japonicum"
        ],
        "definition": "An infection that is caused by Schistosoma japonicum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044344"
    },
    {
      "id": 23345,
      "label": "Schistosoma mansoni infectious disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025901",
          "MESH:D012555",
          "NCIT:C35002",
          "SCTID:750009"
        ],
        "synonyms": [
          "Schistosoma mansoni caused disease or disorder",
          "Schistosoma mansoni disease or disorder",
          "Schistosoma mansoni infection"
        ],
        "definition": "An infection that is caused by Schistosoma mansoni."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044345"
    },
    {
      "id": 23351,
      "label": "Schistosoma intercalatum infectious disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025904",
          "ICD9:120.8",
          "MEDGEN:124448",
          "NCIT:C35364",
          "SCTID:52179003",
          "UMLS:C0276932"
        ],
        "synonyms": [
          "Schistosoma intercalatum caused disease or disorder",
          "Schistosoma intercalatum disease or disorder",
          "infection by Schistosoma intercalatum",
          "infection caused by Schistosoma intercalatum"
        ],
        "definition": "An disease or disorder caused by infection with Schistosoma intercalatum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044351"
    }
  ],
  "roots": [
    {
      "id": 6448,
      "label": "helminthiasis"
    },
    {
      "id": 23869,
      "label": "vector-borne disease"
    }
  ]
}