{
  "id": 15361,
  "label": "pigmented nodular adrenocortical disease, primary, 4",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0014359",
  "properties": {
    "xrefs": [
      "DOID:0070549",
      "GARD:0016016",
      "MEDGEN:862862",
      "OMIM:615830",
      "UMLS:C4014425"
    ],
    "synonyms": [
      "Cushing syndrome, ACTH-independent adrenal, somatic",
      "PRKACA primary pigmented nodular adrenocortical disease",
      "pigmented nodular adrenocortical disease, primary, 4",
      "pigmented nodular adrenocortical disease, primary, type 4",
      "primary pigmented nodular adrenocortical disease caused by mutation in PRKACA",
      "ACTH-independent adrenal Cushing syndrome, somatic",
      "Cushing syndrome, adrenal, due to Ppnad4",
      "PPNAD4",
      "chromosome 19P13 Duplication syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Any primary pigmented nodular adrenocortical disease in which the cause of the disease is a mutation in the PRKACA gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16641,
      "label": "primary pigmented nodular adrenocortical disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7151
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060280",
          "GARD:0010906",
          "MEDGEN:930501",
          "NCIT:C131196",
          "OMIMPS:610489",
          "Orphanet:189439",
          "SCTID:719274008",
          "UMLS:C4304832",
          "icd11.foundation:2003695246"
        ],
        "synonyms": [
          "PPNAD",
          "pigmented nodular adrenocortical disease",
          "pigmented nodular adrenocortical disease, primary",
          "primary pigmented nodular adrenal dysplasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A form of bilateral adrenocortical hyperplasia that is often associated with adrenocorticotrophin hormone (ACTH) independent Cushing syndrome and is characterized by small to normal sized adrenal glands containing multiple small cortical pigmented nodules (less than 1 cm in diameter)."
      },
      "child_count": 10,
      "reference_id": "MONDO:0015999"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16641,
      "label": "primary pigmented nodular adrenocortical disease"
    }
  ]
}