{
  "id": 9558,
  "label": "familial pityriasis rubra pilaris",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008251",
  "properties": {
    "xrefs": [
      "GARD:0024612",
      "MEDGEN:443914",
      "MESH:C531784",
      "MedDRA:10035116",
      "OMIM:173200",
      "Orphanet:2897",
      "UMLS:C2930842"
    ],
    "synonyms": [
      "pityriasis rubra pilaris",
      "Devergie's disease",
      "PRP",
      "hereditary pityriasis rubra pilaris",
      "pityriasis rubra pilaris--familial type"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A rare chronic papulosquamous disorder of unknown etiology characterized by small follicular papules, scaly red-orange patches, and palmoplantar hyperkeratosis, which may progress to plaques or erythroderma. Although most of the cases are sporadic and acquired, a familial form of the disease exists."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 23775,
      "label": "pityriasis rubra pilaris",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19131
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9212",
          "GARD:0007401",
          "ICD10CM:L44.0",
          "ICD9:696.4",
          "MEDGEN:45939",
          "MESH:D010916",
          "NCIT:C85014",
          "NORD:1582",
          "SCTID:3755001",
          "UMLS:C0032027",
          "icd11.foundation:2048594962"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A group of skin conditions that cause constant inflammation and scaling of the skin. People with PRP have reddish, scaly patches that may occur everywhere on the body, or only on certain areas. Some people with PRP also develop thickened skin on the underside of the hands and feet (palmoplantar keratoderma), various nail abnormalities, and/or thinning of the hair. There are several types of PRP classified by age when symptoms begin, body areas involved, and whether other conditions are present. This condition occurs in adults (adult onset PRP) as well as children (juvenile onset PRP)."
      },
      "child_count": 3,
      "reference_id": "MONDO:0100017"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D012873",
          "SCTID:239001006"
        ],
        "synonyms": [
          "disease, genetic skin",
          "diseases, genetic skin",
          "genetic skin disease",
          "genetic skin diseases",
          "genodermatosis",
          "skin disease, genetic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of skin disease that is caused by a modification of the individual's genome."
      },
      "child_count": 228,
      "reference_id": "MONDO:0100118"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 23775,
      "label": "pityriasis rubra pilaris"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder"
    }
  ]
}