{
  "id": 9527,
  "label": "pemphigus vulgaris",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008219",
  "properties": {
    "xrefs": [
      "DOID:0060851",
      "EFO:0004719",
      "GARD:0007355",
      "ICD10CM:L10.0",
      "MEDGEN:10621",
      "MESH:C536645",
      "MedDRA:10052802",
      "NANDO:1200229",
      "NCIT:C34910",
      "OMIM:169610",
      "Orphanet:704",
      "SCTID:49420001",
      "UMLS:C0030809",
      "icd11.foundation:278358681"
    ],
    "synonyms": [
      "pemphigus vulgaris, familial"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Pemphigus is a group of chronic autoimmune skin diseases characterized by blister formations on the outer layer of the skin and the mucous membranes. Three clinical forms have been characterized, of which pemphigus vulgaris is the most frequent (75%)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 8070,
      "label": "pemphigus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19177
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9182",
          "EFO:1000749",
          "GARD:0007352",
          "ICD10CM:L10",
          "ICD10WHO:L10",
          "ICD9:694.4",
          "MEDGEN:45369",
          "MESH:D010392",
          "NANDO:1200228",
          "NCIT:C34909",
          "SCTID:65172003",
          "UMLS:C0030807",
          "Wikipedia:Pemphigus",
          "icd11.foundation:191659986"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Pemphigus is a group of rare autoimmune diseases that cause blistering of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals).This conditioncan occur at any age, but often strikes people in middle or older age. Studies have shown that some populations may be at greater risk for certain types of pemphigus. For instance, people of Jewish descent and those from India, Southeast Europe, and the Middle East are at greater risk for pemphigus vulargis, while pemphigus foliaceus is more common in North America, Turkey, and South America. Pemphigus is a chronic disease which is best controlled by early diagnosis and treatment.Treatment includes steroids to reduce inflammation,drugs that suppress the immune system responseand antibiotics to treat associated infections. There are four main types of pemphigus: Pemphigus vulgaris Pemphigus foliaceus IgA pemphigus Paraneoplastic pemphigus"
      },
      "child_count": 6,
      "reference_id": "MONDO:0006594"
    }
  ],
  "children": [
    {
      "id": 19163,
      "label": "pemphigus vegetans",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9527
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0008613",
          "GARD:0019021",
          "ICD10CM:L10.1",
          "MEDGEN:537814",
          "MedDRA:10057053",
          "NANDO:1200232",
          "Orphanet:79479",
          "SCTID:81285006",
          "UMLS:C0263316",
          "icd11.foundation:1977394957"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0019322"
    }
  ],
  "roots": [
    {
      "id": 8070,
      "label": "pemphigus"
    }
  ]
}