{
  "id": 8053,
  "label": "lipodystrophy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006573",
  "properties": {
    "xrefs": [
      "DOID:811",
      "EFO:1000727",
      "GARD:0027051",
      "HP:0009125",
      "ICD9:272.6",
      "MEDGEN:6111",
      "MESH:D008060",
      "NANDO:1200858",
      "NANDO:2100147",
      "NANDO:2200404",
      "NCIT:C97093",
      "SCTID:71325002",
      "UMLS:C0023787",
      "Wikipedia:Lipodystrophy"
    ],
    "synonyms": [
      "lipodsystrophic syndrome",
      "lipodsystrophic syndromes",
      "lipodystrophy",
      "lipodystrophy (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A congenital or acquired disorder characterized by abnormal loss or redistribution of the adipose tissue in the body."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 6795,
      "label": "metabolic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0014667",
          "EFO:0000589",
          "ICD10CM:E70-E88",
          "ICD10WHO:E70-E90",
          "ICD9:277.8",
          "ICD9:277.9",
          "MEDGEN:44376",
          "MESH:D008659",
          "NANDO:1100002",
          "NCIT:C3235",
          "SCTID:75934005",
          "UMLS:C0025517"
        ],
        "synonyms": [
          "disorder of metabolic process",
          "metabolic disease",
          "metabolic disorder",
          "metabolic process disease",
          "disease of metabolism"
        ],
        "definition": "A congenital disorder (due to inherited enzyme abnormality) or acquired (due to failure of a metabolically important organ) disorder resulting from an abnormal metabolic process."
      },
      "child_count": 37,
      "reference_id": "MONDO:0005066"
    },
    {
      "id": 6820,
      "label": "skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4198
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:37",
          "EFO:0000701",
          "ICD9:702",
          "ICD9:702.8",
          "ICD9:709.8",
          "MEDGEN:20777",
          "MESH:D012871",
          "NANDO:2100281",
          "NCIT:C3371",
          "SCTID:95320005",
          "UMLS:C0037274"
        ],
        "synonyms": [
          "cutaneous disorder",
          "disease of zone of skin",
          "disease or disorder of zone of skin",
          "disorder of skin",
          "disorder of zone of skin",
          "skin diseases and manifestations",
          "skin disorder",
          "zone of skin disease",
          "zone of skin disease or disorder",
          "dermatosis",
          "genodermatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs."
      },
      "child_count": 72,
      "reference_id": "MONDO:0005093"
    }
  ],
  "children": [
    {
      "id": 19064,
      "label": "localized lipodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0005867",
          "MEDGEN:1385527",
          "NCIT:C131814",
          "Orphanet:79088",
          "UMLS:C4329999"
        ],
        "synonyms": [
          "focal lipodystrophy",
          "centrifugal lipodystrophy (subtype)",
          "drug-induced localised lipodystrophy (subtype)",
          "drug-induced localized lipodystrophy (subtype)",
          "idiopathic localised lipodystrophy (subtype)",
          "idiopathic localized lipodystrophy (subtype)",
          "panniculitis and localised lipodystrophy (subtype)",
          "panniculitis and localized lipodystrophy (subtype)",
          "pressure-induced localised lipoatrophy (subtype)",
          "pressure-induced localized lipoatrophy (subtype)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Localised lipodystrophies are characterized by loss of subcutaneous tissue from small regions of the body."
      },
      "child_count": 5,
      "reference_id": "MONDO:0019194"
    },
    {
      "id": 19731,
      "label": "hereditary lipodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8053,
        18954,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012597",
          "MEDGEN:1383706",
          "Orphanet:98305",
          "SCTID:724841000",
          "UMLS:C4511302",
          "icd11.foundation:1166232738"
        ],
        "synonyms": [
          "genetic lipodystrophy",
          "genetic lipodystrophy (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of lipodystrophy that is caused by an inherited genomic modification in an individual."
      },
      "child_count": 33,
      "reference_id": "MONDO:0020087"
    },
    {
      "id": 19733,
      "label": "acquired lipodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7996,
        8053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012602",
          "MEDGEN:798705",
          "MedDRA:10049287",
          "Orphanet:98307",
          "UMLS:C0877192"
        ],
        "synonyms": [
          "acquired lipodystrophy (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of lipodystrophy (disease) that is acquired during the lifetime of the individual."
      },
      "child_count": 4,
      "reference_id": "MONDO:0020089"
    },
    {
      "id": 21769,
      "label": "generalized lipodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080298",
          "GARD:0027920",
          "HP:0009064",
          "MEDGEN:1369615",
          "NCIT:C131815",
          "UMLS:C4317112"
        ],
        "synonyms": [
          "complete generalised lipodystrophy",
          "complete generalized lipodystrophy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Almost complete absence of subcutaneous and/or visceral adipose tissue."
      },
      "child_count": 2,
      "reference_id": "MONDO:0027766"
    },
    {
      "id": 21770,
      "label": "partial lipodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080299",
          "GARD:0027921",
          "MEDGEN:1386287",
          "NCIT:C131296",
          "UMLS:C4316789"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Loss and redistribution of subcutaneous and/or visceral adipose tissue from specific regions of the body."
      },
      "child_count": 2,
      "reference_id": "MONDO:0027767"
    }
  ],
  "roots": [
    {
      "id": 6795,
      "label": "metabolic disease"
    },
    {
      "id": 6820,
      "label": "skin disorder"
    }
  ]
}