{
  "id": 7751,
  "label": "endometrial serous adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006196",
  "properties": {
    "xrefs": [
      "DOID:5750",
      "EFO:1000238",
      "MEDGEN:1659908",
      "NCIT:C27838",
      "ONCOTREE:USC",
      "UMLS:C0854924",
      "icd11.foundation:225222541"
    ],
    "synonyms": [
      "uterine serous adenocarcinoma",
      "uterine serous carcinoma",
      "body of uterus serous adenocarcinoma",
      "endometrial serous adenocarcinoma",
      "serous endometrial adenocarcinoma",
      "uterine corpus serous adenocarcinoma",
      "uterine papillary serous carcinoma",
      "uterine serous papillary adenocarcinoma",
      "uterine serous carcinoma/uterine papillary serous carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A high grade, aggressive adenocarcinoma arising from the endometrium. It is characterized by the presence of complex papillary patterns with cellular budding. Atypical mitoses, necrosis, and psammoma bodies may be present. It is classified as type II endometrial carcinoma and it is not associated with endometrial hyperplasia. It tends to invade deeply into the myometrium and spreads into the lymphatic vessels. Patients frequently present with spread of the tumor beyond the uterus at the time of diagnosis. The prognosis is usually poor."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6929,
      "label": "uterine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4754,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0002919",
          "MEDGEN:755620",
          "SCTID:446022000",
          "UMLS:C2960452"
        ],
        "synonyms": [
          "carcinoma of uterus",
          "uterus carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A carcinoma involving a uterus."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005213"
    },
    {
      "id": 6974,
      "label": "serous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3114",
          "EFO:0003825",
          "NCIT:C40101"
        ],
        "synonyms": [
          "serous adenocarcinoma",
          "serous carcinoma",
          "serous cystadenocarcinoma",
          "serous cystadenocarcinoma, NOS (morphologic abnormality)"
        ],
        "definition": "An adenocarcinoma that is characterized by the presence of papillary patterns and cellular budding. Psammoma bodies may be present. Representative examples include cervical serous adenocarcinoma, endometrial serous adenocarcinoma, ovarian serous adenocarcinoma, and primary peritoneal serous adenocarcinoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005278"
    },
    {
      "id": 7594,
      "label": "uterine corpus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4754,
        20461
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9460",
          "EFO:0007532",
          "ICD9:182",
          "NCIT:C61574",
          "SCTID:371972005"
        ],
        "synonyms": [
          "body of uterus cancer",
          "cancer of body of uterus",
          "cancer of the corpus uteri",
          "corpus uteri cancer",
          "malignant body of uterus neoplasm",
          "malignant neoplasm of body of uterus",
          "uterine (including endometrial) cancer",
          "uterine corpus cancer",
          "endometrial cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the body of uterus."
      },
      "child_count": 24,
      "reference_id": "MONDO:0006003"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6929,
      "label": "uterine carcinoma"
    },
    {
      "id": 6974,
      "label": "serous adenocarcinoma"
    },
    {
      "id": 7594,
      "label": "uterine corpus cancer"
    }
  ]
}