{
  "id": 7673,
  "label": "basaloid carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006102",
  "properties": {
    "xrefs": [
      "EFO:1000105",
      "ICDO:8123/3",
      "MEDGEN:316439",
      "NCIT:C4121",
      "UMLS:C1704216"
    ],
    "synonyms": [
      "basaloid carcinoma"
    ],
    "definition": "A malignant epithelial neoplasm characterized by the presence of neoplastic cells with hyperchromatic nuclei, small amount of cytoplasm, and peripheral nuclear palisading."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    }
  ],
  "children": [
    {
      "id": 5405,
      "label": "basaloid squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        7673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5522",
          "EFO:1001940",
          "ICDO:8083/3",
          "MEDGEN:266085",
          "NCIT:C54244",
          "UMLS:C1266005",
          "icd11.foundation:1738201981"
        ],
        "synonyms": [
          "basaloid carcinoma",
          "basaloid carcinoma (morphologic abnormality)",
          "basaloid squamous cell carcinoma",
          "basaloid squamous cell carcinoma (morphologic abnormality)"
        ],
        "definition": "A squamous cell carcinoma characterized by the presence of cells with hyperchromatic nuclei, scant amount of cytoplasm, and peripheral nuclear palisading."
      },
      "child_count": 14,
      "reference_id": "MONDO:0003486"
    },
    {
      "id": 5922,
      "label": "basaloid large cell lung carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5040,
        7673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7045",
          "MEDGEN:231419",
          "NCIT:C7266",
          "ONCOTREE:BLCLC",
          "UMLS:C1332463"
        ],
        "synonyms": [
          "basaloid large cell lung carcinoma",
          "basaloid large cell carcinoma of the lung",
          "basaloid lung carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A morphologic variant of large cell lung carcinoma characterized by the presence of a solid nodular or anastomotic trabecular growth pattern, peripheral palisading, and comedo type necrosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004087"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    }
  ]
}