{
  "id": 7249,
  "label": "varicella zoster infection",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005608",
  "properties": {
    "xrefs": [
      "EFO:0006509",
      "ICD9:052.7",
      "MEDGEN:668886",
      "NCIT:C96407",
      "SCTID:309465005",
      "UMLS:C0586989"
    ],
    "synonyms": [
      "Varicella-zoster Virus infection",
      "varicella zoster infection"
    ],
    "definition": "A highly contagious viral infection caused by the varicella zoster virus. Clinically, it may be manifested as shingles or chicken pox."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 7411,
      "label": "Herpesviridae infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007309",
          "MESH:D006566",
          "SCTID:23513009"
        ],
        "synonyms": [
          "Herpesviridae caused disease or disorder",
          "Herpesviridae disease or disorder",
          "Herpesviridae infections",
          "herpesvirus infection",
          "Herpesviridae infection",
          "Herpesvirus infection",
          "Herpesvirus infections",
          "herpes infection",
          "infection, Herpesviridae",
          "infection, Herpesvirus",
          "infections, Herpesviridae",
          "infections, Herpesvirus"
        ],
        "definition": "Virus diseases caused by the herpesviridae."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005794"
    }
  ],
  "children": [
    {
      "id": 7250,
      "label": "herpes zoster",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7249,
        8092,
        20721,
        21328,
        24063
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8536",
          "EFO:0006510",
          "ICD10CM:B02",
          "ICD9:053",
          "MEDGEN:42437",
          "MESH:D006562",
          "NCIT:C71079",
          "SCTID:4740000",
          "UMLS:C0019360"
        ],
        "synonyms": [
          "Zoster",
          "herpes Zoster",
          "shingles",
          "postherpetic neuralgia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A common dermal and neurologic disorder caused by reactivation of the varicella-zoster virus that has remained dormant within dorsal root ganglia, often for decades, after the patient's initial exposure to the virus in the form of varicella (chickenpox). It is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area."
      },
      "child_count": 15,
      "reference_id": "MONDO:0005609"
    },
    {
      "id": 7331,
      "label": "chickenpox",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7249,
        8092,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8659",
          "EFO:0007204",
          "ICD10CM:B01",
          "ICD9:052",
          "ICD9:052.9",
          "MEDGEN:2995",
          "MESH:D002644",
          "NCIT:C97132",
          "SCTID:38907003",
          "UMLS:C0008049"
        ],
        "synonyms": [
          "Varicella",
          "chicken pox",
          "chicken pox infection",
          "chickenpox",
          "varicella"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rash, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005700"
    },
    {
      "id": 20280,
      "label": "herpes zoster dermatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7249,
        20419
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:208894",
          "NCIT:C35619",
          "UMLS:C0854330"
        ],
        "synonyms": [
          "herpes zoster dermatitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Painful, localized rash caused by reactivation of latent varicella zoster virus residing in nerve cell bodies, with resulting infection of the skin in the region supplied by the affected nerve."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021033"
    },
    {
      "id": 20405,
      "label": "herpetic vulvovaginitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7249,
        8440,
        21231
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:054.11",
          "MEDGEN:42440",
          "NCIT:C34697",
          "SCTID:27420004",
          "UMLS:C0019386"
        ],
        "synonyms": [
          "herpetic vulvovaginitis",
          "Herpetic Vulvovaginitis",
          "Herpetic vulvovaginitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Infection of the vulva and the vagina caused by herpes simplex virus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021175"
    }
  ],
  "roots": [
    {
      "id": 7411,
      "label": "Herpesviridae infectious disease"
    }
  ]
}