{
  "id": 6856,
  "label": "cytomegalovirus infection",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005132",
  "properties": {
    "xrefs": [
      "EFO:0001062",
      "ICD9:078.5",
      "MEDGEN:8239",
      "MESH:D003586",
      "NCIT:C53649",
      "SCTID:28944009",
      "UMLS:C0010823"
    ],
    "synonyms": [
      "CMV infection",
      "Cytomegaloviral infection",
      "HCMV infection"
    ],
    "definition": "A herpesvirus infection caused by Cytomegalovirus. Healthy individuals generally do not produce symptoms. However, the infection may be life-threatening in affected immunocompromised patients. The virus may cause retinitis, esophagitis, gastritis, and colitis. Morphologically, it is characterized by the presence of intranuclear inclusion bodies."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 7411,
      "label": "Herpesviridae infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007309",
          "MESH:D006566",
          "SCTID:23513009"
        ],
        "synonyms": [
          "Herpesviridae caused disease or disorder",
          "Herpesviridae disease or disorder",
          "Herpesviridae infections",
          "herpesvirus infection",
          "Herpesviridae infection",
          "Herpesvirus infection",
          "Herpesvirus infections",
          "herpes infection",
          "infection, Herpesviridae",
          "infection, Herpesvirus",
          "infections, Herpesviridae",
          "infections, Herpesvirus"
        ],
        "definition": "Virus diseases caused by the herpesviridae."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005794"
    }
  ],
  "children": [
    {
      "id": 3166,
      "label": "cytomegalovirus retinitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4749,
        6856,
        16683,
        19708,
        20248
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080160",
          "EFO:1001302",
          "GARD:0009531",
          "MEDGEN:61532",
          "MESH:D017726",
          "NCIT:C50521",
          "SCTID:22455005",
          "UMLS:C0206178",
          "icd11.foundation:315493536"
        ],
        "synonyms": [
          "Cytomegaloviral Retinitis",
          "Cytomegalovirus caused retinitis",
          "Cytomegalovirus retinitis",
          "Retinitis, Cytomegaloviral",
          "cytomegalovirus retinitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Infection of the retina by cytomegalovirus characterized by retinal necrosis, hemorrhage, vessel sheathing, and retinal edema. Cytomegalovirus retinitis is a major opportunistic infection in aids patients and can cause blindness."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000878"
    },
    {
      "id": 17716,
      "label": "fetal cytomegalovirus syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        6856,
        23097
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0001480",
          "MEDGEN:578789",
          "NANDO:2200891",
          "NCIT:C122427",
          "Orphanet:294",
          "SCTID:276701009",
          "UMLS:C0349499",
          "icd11.foundation:1515465998"
        ],
        "synonyms": [
          "antenatal CMV infection",
          "antenatal cytomegalovirus infection",
          "congenital Cytomegaloviral infection",
          "mother-to-child transmission of cytomegalovirus syndrome",
          "CMV antenatal infection",
          "congenital cytomegalovirus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "An infection with the Cytomegalovirus that is present from birth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017409"
    },
    {
      "id": 18265,
      "label": "idiopathic disseminated cytomegalovirus infection",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6856,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018811",
          "MEDGEN:1826159",
          "Orphanet:35062",
          "UMLS:C5680152"
        ],
        "synonyms": [
          "idiopathic disseminated CMV infection"
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018108"
    },
    {
      "id": 21377,
      "label": "cytomegalovirus pneumonia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6856,
        7603
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:124443",
          "NCIT:C35360",
          "SCTID:7678002",
          "UMLS:C0276253"
        ],
        "synonyms": [
          "CMV pneumonia",
          "Cytomegaloviral pneumonia",
          "Cytomegalovirus caused pneumonia",
          "Cytomegalovirus pneumonia",
          "cytomegalovirus pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Pneumonia caused by cytomegalovirus. Most humans are exposed to cytomegalovirus. Healthy individuals do not develop signs and symptoms of infection. Patients with weakened immune system (e.g., AIDS patients, cancer patients who are being treated with chemotherapy, and patients who have received bone marrow or solid organ transplants) develop signs and symptoms of infection. They include cough, shortness of breath, fatigue, malaise, fever, muscle and joint pain, and excessive sweating."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024354"
    }
  ],
  "roots": [
    {
      "id": 7411,
      "label": "Herpesviridae infectious disease"
    }
  ]
}