{
  "id": 6776,
  "label": "hypertensive disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005044",
  "properties": {
    "xrefs": [
      "DOID:10763",
      "EFO:0000537",
      "HP:0000822",
      "ICD10CM:I10-I16",
      "ICD10CM:I15",
      "ICD9:401-405",
      "ICD9:997.91",
      "MEDGEN:6969",
      "MESH:D006973",
      "NCIT:C3117",
      "SCTID:38341003",
      "UMLS:C0020538"
    ],
    "synonyms": [
      "HTN",
      "blood pressure, high",
      "blood pressure, increased",
      "high blood pressure",
      "hypertensive disease",
      "increased blood pressure",
      "pressure, high blood",
      "vascular hypertensive disorder",
      "hypertension"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 12,
  "parents": [
    {
      "id": 2933,
      "label": "arterial disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050828",
          "ICD9:447.8",
          "ICD9:447.9",
          "MEDGEN:208875",
          "NCIT:C35317",
          "SCTID:359557001",
          "UMLS:C0852949"
        ],
        "synonyms": [
          "arterial disease",
          "arterial disorder",
          "arteriopathy",
          "artery disease",
          "artery disease or disorder",
          "disease of artery",
          "disease or disorder of artery",
          "disorder of artery"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An impairment of the structure or function of the blood vessels which carry blood away from the heart."
      },
      "child_count": 30,
      "reference_id": "MONDO:0000473"
    }
  ],
  "children": [
    {
      "id": 3380,
      "label": "essential hypertension",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10825",
          "ICD9:401",
          "ICD9:401.9",
          "MEDGEN:88442",
          "MESH:D000075222",
          "Orphanet:243761",
          "SCTID:59621000",
          "UMLS:C0085580",
          "icd11.foundation:761947693"
        ],
        "synonyms": [
          "idiopathic hypertension",
          "primary hypertension"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Hypertension that presents without an identifiable cause."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001134"
    },
    {
      "id": 3441,
      "label": "secondary hypertension",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11130",
          "EFO:1002034",
          "ICD10WHO:I15",
          "ICD9:405",
          "ICD9:405.9",
          "ICD9:405.99",
          "MEDGEN:57609",
          "SCTID:31992008",
          "UMLS:C0155616",
          "icd11.foundation:1331849426"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "High blood pressure caused by an underlying medical condition."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001200"
    },
    {
      "id": 6873,
      "label": "pulmonary hypertension",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6432",
          "GARD:0027347",
          "MEDGEN:9376",
          "MESH:D006976",
          "MedDRA:10037400",
          "SCTID:70995007",
          "UMLS:C0020542",
          "icd11.foundation:1496633964"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Increased pressure within the pulmonary circulation due to lung or heart disorder."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005149"
    },
    {
      "id": 7098,
      "label": "early onset hypertension",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004772"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A form of hypertension with early onset relative to normal range for a given population."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005430"
    },
    {
      "id": 7230,
      "label": "chemotherapy-induced hypertension",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A form of hypertension that occurs as a direct result of chemotherapy treatment"
      },
      "child_count": 0,
      "reference_id": "MONDO:0005585"
    },
    {
      "id": 8258,
      "label": "intracranial hypertension",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6776,
        7209,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9428",
          "EFO:1000992",
          "MEDGEN:56241",
          "MESH:D019586",
          "MedDRA:10022764",
          "UMLS:C0151740"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A finding characterized by increased cerebrospinal fluid pressure within the skull."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006810"
    },
    {
      "id": 8290,
      "label": "malignant hypertension",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10824",
          "EFO:1001031",
          "MEDGEN:9374",
          "MESH:D006974",
          "MedDRA:10025600",
          "SCTID:70272006",
          "UMLS:C0020540"
        ],
        "synonyms": [
          "MHT",
          "accelerated-malignant hypertension",
          "hypertensive emergency",
          "malignant phase hypertension"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Severe hypertension that is characterized by rapid onset of extremely high blood pressure and hypertension-mediated organ damage."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006846"
    },
    {
      "id": 8314,
      "label": "ocular hypertension",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6776,
        7019
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9282",
          "EFO:1001069",
          "ICD10CM:H40.05",
          "ICD9:365.04",
          "MEDGEN:10423",
          "MESH:D009798",
          "MedDRA:10030043",
          "SCTID:4210003",
          "UMLS:C0028840",
          "icd11.foundation:535283437"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Abnormally high intraocular pressure."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006875"
    },
    {
      "id": 21224,
      "label": "kallikrein hypertension",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "HGNC:6357",
          "MEDGEN:257936",
          "MESH:C537707",
          "UMLS:C1171349"
        ],
        "synonyms": [
          "kallikrein attenuated hypertension"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0023530"
    },
    {
      "id": 21571,
      "label": "hypertension, pregnancy-induced",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6776,
        21520
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:852894",
          "MESH:D046110",
          "NCIT:C9243",
          "SCTID:48194001",
          "UMLS:C0852036"
        ],
        "synonyms": [
          "hypertension associated disorders of pregnancy",
          "hypertension-associated pregnancy disorder",
          "pregnancy-induced hypertension",
          "gestational hypertension",
          "hypertension complicating pregnancy",
          "hypertension induced by pregnancy",
          "hypertension, gestational",
          "hypertension, pregnancy induced",
          "hypertension, pregnancy transient",
          "hypertensions, pregnancy induced",
          "induced Hypertensions, pregnancy",
          "induced hypertension, pregnancy",
          "pregnancy induced hypertension",
          "pregnancy transient hypertension",
          "transient hypertension, pregnancy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A hypertensive disorder that develops during pregnancy."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024664"
    },
    {
      "id": 23830,
      "label": "resistant hypertension",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "drug resistant hypertension"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A severe medical condition which is estimated to appear in 9-18% of hypertensive patients, in which treatment with 3 or more antihypertensive drugs including diuretics are ineffective."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100078"
    },
    {
      "id": 29226,
      "label": "hypertensive urgency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:677063",
          "NCIT:C197914",
          "SCTID:443482000",
          "UMLS:C0745138",
          "icd11.foundation:956687992"
        ],
        "synonyms": [
          "hypertensive crisis without acute organ damage",
          "severely elevated blood pressure without acute organ damage"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A hypertensive disorder that is characterized by marked elevation in blood pressure, such as systolic blood pressure greater than 180 mmHg or diastolic blood pressure greater than 110 mmHg, and without evidence of target organ damage, such as pulmonary edema, cardiac ischemia, neurologic deficits, or acute renal failure."
      },
      "child_count": 0,
      "reference_id": "MONDO:1030007"
    }
  ],
  "roots": [
    {
      "id": 2933,
      "label": "arterial disorder"
    }
  ]
}