{
  "id": 6684,
  "label": "substance dependence",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004938",
  "properties": {
    "xrefs": [
      "DOID:9973",
      "ICD9:304.60",
      "MEDGEN:20989",
      "NCIT:C35458",
      "SCTID:2403008",
      "UMLS:C0038580"
    ],
    "synonyms": [
      "dependence"
    ],
    "definition": "The psychological or physiological need to take a substance in order to experience its effects or to avoid the effects of its absence."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4573,
      "label": "substance-related disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4172
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:303",
          "ICD10CM:F10-F19",
          "MEDGEN:66746",
          "MESH:D019966",
          "NCIT:C92203",
          "UMLS:C0236969"
        ],
        "synonyms": [
          "substance induced mood disorders",
          "substance-related disorder"
        ],
        "definition": "A category of psychiatric disorders which include disorders related to the taking of a drug of abuse (including alcohol, prescribed medications and recreational drugs)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002494"
    }
  ],
  "children": [
    {
      "id": 6997,
      "label": "drug dependence",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6684
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9974",
          "EFO:0003890",
          "ICD9:304",
          "ICD9:304.6",
          "ICD9:304.60",
          "ICD9:304.90",
          "MEDGEN:307144",
          "NCIT:C3894",
          "SCTID:191816009",
          "UMLS:C1510472"
        ],
        "synonyms": [
          "chemical dependence"
        ],
        "definition": "Drug dependence - replaced the term \"drug addiction\" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005303"
    }
  ],
  "roots": [
    {
      "id": 4573,
      "label": "substance-related disorder"
    }
  ]
}