{
  "id": 6468,
  "label": "lattice corneal dystrophy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004686",
  "properties": {
    "xrefs": [
      "DOID:8943",
      "GARD:0024087",
      "HP:0001149",
      "ICD10CM:H18.54",
      "ICD9:277.39",
      "ICD9:357.4",
      "MEDGEN:56355",
      "SCTID:1192004",
      "UMLS:C0155127",
      "icd11.foundation:1247885635"
    ],
    "synonyms": [
      "lattice corneal dystrophy",
      "lattice corneal dystrophy (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 19763,
      "label": "stromal corneal dystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060442",
          "GARD:0019519",
          "ICD9:371.56",
          "MEDGEN:20973",
          "Orphanet:98626",
          "SCTID:231931001",
          "UMLS:C0038457",
          "icd11.foundation:1392780216"
        ],
        "synonyms": [
          "corneal dystrophy (disease) of substantia propria of cornea",
          "corneal stromal dystrophy",
          "substantia propria of cornea corneal dystrophy (disease)",
          "stromal dystrophy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "The stromal corneal dystrophies refer to a group of rare genetically determined corneal dystrophies (CDs) characterized by lesions affecting the corneal stroma, and variable effects on vision depending on the type of dystrophy."
      },
      "child_count": 10,
      "reference_id": "MONDO:0020213"
    }
  ],
  "children": [
    {
      "id": 8773,
      "label": "lattice corneal dystrophy type I",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3131,
        6468
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009678",
          "MEDGEN:305533",
          "MESH:C537881",
          "OMIM:122200",
          "Orphanet:98964",
          "SCTID:419197009",
          "UMLS:C1690006"
        ],
        "synonyms": [
          "Biber-Haab-Dimmer dystrophy",
          "LCD1",
          "LCDI",
          "Lcd1",
          "classic lattice corneal dystrophy",
          "lattice corneal dystrophy type 1",
          "CDL1",
          "LCD",
          "corneal dystrophy, lattice type 1",
          "corneal dystrophy, lattice type I",
          "lattice corneal dystrophy, type 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Type I lattice corneal dystrophy (LCDI) is a frequent form of stromal corneal dystrophy characterized by a network of delicate interdigitating branching filamentous opacities within the cornea with progressive visual impairment and no systemic manifestations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007380"
    },
    {
      "id": 10049,
      "label": "gelatinous drop-like corneal dystrophy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3130,
        5714,
        6468,
        19762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060449",
          "GARD:0009647",
          "MEDGEN:90939",
          "MESH:C535480",
          "NANDO:1201006",
          "NCIT:C142805",
          "OMIM:204870",
          "Orphanet:98957",
          "UMLS:C0339273",
          "icd11.foundation:1062815669"
        ],
        "synonyms": [
          "GDCD",
          "corneal amyloidosis",
          "gelatinous drop-like corneal dystrophy",
          "primary familial amyloidosis of the cornea",
          "subepithelial amyloidosis of the cornea",
          "CDGDL",
          "Cdgdl",
          "GDLD",
          "amyloid corneal dystrophy, Japanese type",
          "amyloidosis corneal",
          "amyloidosis, corneal",
          "corneal dystrophy, gelatinous drop-like",
          "corneal dystrophy, lattice type 3",
          "lattice corneal dystrophy type 3",
          "lattice corneal dystrophy, type 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Gelatinous drop-like corneal dystrophy (GDCD) is a form of superficial corneal dystrophy characterized by multiple prominent milky-white gelatinous nodules beneath the corneal epithelium, and marked visual impairment."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008777"
    },
    {
      "id": 13112,
      "label": "corneal dystrophy, lattice type 3A",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3131,
        6468
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010320",
          "MEDGEN:332989",
          "MESH:C563923",
          "OMIM:608471",
          "UMLS:C1837974"
        ],
        "synonyms": [
          "CDL3A",
          "corneal dystrophy, lattice type IIIA",
          "lattice corneal dystrophy type 3A",
          "lattice corneal dystrophy type III A",
          "lattice corneal dystrophy, type 3A"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Lattice corneal dystrophy type 3A is rare condition that affects the cornea. It is characterized primarily by protein clumps in the clear, outer covering of the eye which cloud the cornea and impair vision. Affected people also experience recurrent corneal erosion (separation of certain layers of the cornea), which is associated with severe pain and sensitivity to bright light. Lattice corneal dystrophy type 3A is caused by changes (mutations) in the TGFBI gene and is inherited in an autosomal dominant manner. The condition is usually treated surgically."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012044"
    }
  ],
  "roots": [
    {
      "id": 19763,
      "label": "stromal corneal dystrophy"
    }
  ]
}