{
  "id": 5584,
  "label": "thyroid gland diffuse sclerosing papillary carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003701",
  "properties": {
    "xrefs": [
      "DOID:5914",
      "GARD:0023623",
      "ICDO:8350/3",
      "MEDGEN:87218",
      "NCIT:C7427",
      "UMLS:C0334330"
    ],
    "synonyms": [
      "nonencapsulated sclerosing adenocarcinoma",
      "nonencapsulated sclerosing carcinoma",
      "nonencapsulated sclerosing neoplasm",
      "nonencapsulated sclerosing papillary thyroid carcinoma",
      "nonencapsulated sclerosing tumor",
      "nonencapsulated sclerosing tumour",
      "thyroid gland diffuse sclerosing papillary carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A morphologic variant of papillary carcinoma of the thyroid gland that more often affects young patients and commonly metastasizing to the lungs. It is characterized by a diffuse infiltration of the thyroid gland by malignant follicular cells, squamous metaplasia, stromal fibrosis, and lymphocytic infiltration."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6803,
      "label": "thyroid gland papillary carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4583,
        16290,
        21537
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3969",
          "EFO:0000641",
          "GARD:0024148",
          "HP:0002895",
          "MEDGEN:66773",
          "NCIT:C4035",
          "ONCOTREE:THPA",
          "SCTID:255029007",
          "UMLS:C0238463"
        ],
        "synonyms": [
          "papillary cancer of the thyroid",
          "papillary cancer of the thyroid gland",
          "papillary cancer of thyroid",
          "papillary cancer of thyroid gland",
          "papillary carcinoma of the thyroid",
          "papillary carcinoma of the thyroid gland",
          "papillary carcinoma of thyroid",
          "papillary carcinoma of thyroid gland",
          "papillary thyroid cancer",
          "papillary thyroid carcinoma",
          "papillary thyroid gland carcinoma",
          "thyroid gland papillary cancer",
          "thyroid gland papillary carcinoma",
          "thyroid papillary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. Radiation exposure is a risk factor and it is the most common malignant thyroid lesion, comprising 75% to 80% of all thyroid cancers in iodine sufficient countries. Diagnostic procedures include thyroid ultrasound and fine needle biopsy. Microscopically, the diagnosis is based on the distinct characteristics of the malignant cells, which include enlargement, oval shape, elongation, and overlapping of the nuclei. The nuclei also display clearing or have a ground glass appearance."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005075"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6803,
      "label": "thyroid gland papillary carcinoma"
    }
  ]
}