{
  "id": 4573,
  "label": "substance-related disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002494",
  "properties": {
    "xrefs": [
      "DOID:303",
      "ICD10CM:F10-F19",
      "MEDGEN:66746",
      "MESH:D019966",
      "NCIT:C92203",
      "UMLS:C0236969"
    ],
    "synonyms": [
      "substance induced mood disorders",
      "substance-related disorder"
    ],
    "definition": "A category of psychiatric disorders which include disorders related to the taking of a drug of abuse (including alcohol, prescribed medications and recreational drugs)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4172,
      "label": "psychiatric disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:150",
          "MESH:D001523",
          "MFOMD:0000004",
          "NCIT:C2893"
        ],
        "synonyms": [
          "Psychiatric disease",
          "Psychiatric disorder",
          "disease of mental health",
          "mental disorder",
          "mental dysfunction",
          "mental illness"
        ],
        "definition": "A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia."
      },
      "child_count": 14,
      "reference_id": "MONDO:0002025"
    }
  ],
  "children": [
    {
      "id": 4570,
      "label": "substance abuse",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4573
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:302",
          "ICD9:305.90",
          "MEDGEN:152849",
          "SCTID:66214007",
          "UMLS:C0740858"
        ],
        "definition": "The use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002491"
    },
    {
      "id": 6684,
      "label": "substance dependence",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4573
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9973",
          "ICD9:304.60",
          "MEDGEN:20989",
          "NCIT:C35458",
          "SCTID:2403008",
          "UMLS:C0038580"
        ],
        "synonyms": [
          "dependence"
        ],
        "definition": "The psychological or physiological need to take a substance in order to experience its effects or to avoid the effects of its absence."
      },
      "child_count": 1,
      "reference_id": "MONDO:0004938"
    },
    {
      "id": 7215,
      "label": "substance withdrawal syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        4573
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060001",
          "EFO:0005800",
          "ICD9:292.0",
          "MEDGEN:20990",
          "MESH:D013375",
          "NCIT:C35046",
          "SCTID:363101005",
          "UMLS:C0038587"
        ],
        "synonyms": [
          "drug withdrawal",
          "drug withdrawal syndrome",
          "substance withdrawal",
          "substance withdrawal disorder",
          "substance withdrawal syndrome",
          "withdrawal syndrome",
          "withdrawal disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A substance-specific organic brain syndrome that follows the discontinuation of administration or use, or reduction in intake of a substance (including alcohol, prescribed medications and recreational drugs). Syndrome manifests with diverse, often painful physical and psychological symptoms, which include but not limited to intense drug craving, anxiety, depression, insomnia, nausea, perspiration, body aches, tremors, hallucinations, and convulsions."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005567"
    },
    {
      "id": 20729,
      "label": "alcohol-related disorders",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4573
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:68632",
          "MESH:D019973",
          "SCTID:29212009",
          "UMLS:C0236664"
        ],
        "synonyms": [
          "alcohol related disorders",
          "alcohol-related disorder",
          "disorder, alcohol-related",
          "disorders, alcohol-related"
        ],
        "definition": "Disorders related to or resulting from abuse or mis-use of alcohol."
      },
      "child_count": 8,
      "reference_id": "MONDO:0021698"
    }
  ],
  "roots": [
    {
      "id": 4172,
      "label": "psychiatric disorder"
    }
  ]
}