{
  "id": 4557,
  "label": "prostate neuroendocrine neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002477",
  "properties": {
    "xrefs": [
      "DOID:2992",
      "GARD:0023144",
      "MEDGEN:277537",
      "NCIT:C5545",
      "ONCOTREE:PRNE",
      "UMLS:C1335515"
    ],
    "synonyms": [
      "neuroendocrine neoplasm of prostate",
      "neuroendocrine neoplasm of prostate gland",
      "neuroendocrine neoplasm of the prostate",
      "neuroendocrine tumour of the prostate",
      "prostate gland NET",
      "prostate gland neuroendocrine neoplasm",
      "prostate gland neuroendocrine tumor",
      "prostate gland neuroendocrine tumor, well differentiated, low or intermediate grade",
      "prostate gland neuroendocrine tumour",
      "prostate neuroendocrine neoplasm",
      "prostate neuroendocrine carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neoplasm with neuroendocrine differentiation that arises from the prostate gland. This category includes carcinoid tumors and small cell carcinomas."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 19314,
      "label": "neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:169",
          "EFO:1001901",
          "GARD:0009316",
          "ICD9:209",
          "ICD9:209-209",
          "ICD9:239.7",
          "MEDGEN:64652",
          "MESH:D018358",
          "NCIT:C188218",
          "NCIT:C3809",
          "Orphanet:877",
          "SCTID:255046005",
          "UMLS:C0206754"
        ],
        "synonyms": [
          "APUDoma",
          "neuroendocrine neoplasm",
          "neuroendocrine tumor",
          "neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Endocrine tumors, also referred to as neuroendocrine tumors (NETs), are defined by a common phenotype which is characterized by the expression of general markers (neuron specific enolase, chromogranin, synaptophysin) and hormone secretion products. These tumors may be localized in any part of the body and are generally discovered in non-specific situations, i.e. not immediately suggestive of NETs (tests for inherited predisposition to tumors or for a clinical syndrome caused by abnormal hormone secretion)."
      },
      "child_count": 14,
      "reference_id": "MONDO:0019496"
    },
    {
      "id": 20463,
      "label": "prostate neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5087,
        7638
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13206",
          "ICD9:600.1",
          "MEDGEN:18697",
          "NCIT:C3343",
          "ONCOTREE:PROSTATE",
          "UMLS:C0033578"
        ],
        "synonyms": [
          "neoplasm of prostate",
          "neoplasm of prostate gland",
          "neoplasm of the prostate",
          "prostate gland neoplasm",
          "prostate gland neoplasm (disease)",
          "prostate gland tumor",
          "prostate gland tumour",
          "prostate tumor",
          "prostate tumour",
          "tumor of prostate",
          "tumor of prostate gland",
          "tumor of the prostate",
          "tumour of prostate",
          "tumour of prostate gland",
          "tumour of the prostate",
          "nodular prostate",
          "prostate nodule"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the prostate gland."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021259"
    }
  ],
  "children": [
    {
      "id": 7910,
      "label": "prostate small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4557,
        6882
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7141",
          "EFO:1000499",
          "GARD:0024395",
          "MEDGEN:266251",
          "NCIT:C6766",
          "ONCOTREE:PRSCC",
          "SCTID:396198006",
          "UMLS:C1300585"
        ],
        "synonyms": [
          "Oat cell carcinoma of prostate",
          "Oat cell carcinoma of the prostate",
          "prostate Oat cell carcinoma",
          "prostate gland small cell carcinoma",
          "prostate oat cell carcinoma",
          "prostate small cell NEC",
          "prostate small cell carcinoma",
          "prostate small cell neuroendocrine carcinoma",
          "small cell carcinoma of prostate",
          "small cell carcinoma of prostate gland",
          "small cell carcinoma of the prostate",
          "PRSCC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroendocrine carcinoma of the prostate gland with unfavorable prognosis, composed of small cells containing neurosecretory granules. Approximately half of the cases show a mixture of small cells and adenocarcinoma cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006390"
    }
  ],
  "roots": [
    {
      "id": 19314,
      "label": "neuroendocrine neoplasm"
    },
    {
      "id": 20463,
      "label": "prostate neoplasm"
    }
  ]
}