{ "id": 4496, "label": "dermatitis", "model": { "label": "Mondo Disease Ontology (MONDO)", "source": 0 }, "type_id": 0, "reference_id": "MONDO:0002406", "properties": { "xrefs": [ "DOID:2723", "ICD9:692.9", "MEDGEN:849741", "MESH:D003872", "NCIT:C2983", "SCTID:43116000", "UMLS:C3875321" ], "synonyms": [ "inflammation of skin", "inflammation of the skin", "inflammation of zone of skin", "inflammatory skin disease", "skin inflammation", "zone of skin inflammation" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "An inflammatory process affecting the skin. Signs include red rash, itching, and blister formation. Representative examples are contact dermatitis, atopic dermatitis, and seborrheic dermatitis." }, "isLeaf": false, "isRoot": false, "child_count": 33, "parents": [ { "id": 6820, "label": "skin disorder", "isLeaf": false, "isRoot": false, "parents": [ 4198 ], "type_id": 0, "properties": { "xrefs": [ "DOID:37", "EFO:0000701", "ICD9:702", "ICD9:702.8", "ICD9:709.8", "MEDGEN:20777", "MESH:D012871", "NANDO:2100281", "NCIT:C3371", "SCTID:95320005", "UMLS:C0037274" ], "synonyms": [ "cutaneous disorder", "disease of zone of skin", "disease or disorder of zone of skin", "disorder of skin", "disorder of zone of skin", "skin diseases and manifestations", "skin disorder", "zone of skin disease", "zone of skin disease or disorder", "dermatosis", "genodermatosis" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs." }, "child_count": 72, "reference_id": "MONDO:0005093" }, { "id": 20399, "label": "inflammatory disease", "isLeaf": false, "isRoot": false, "parents": [ 29380 ], "type_id": 0, "properties": { "xrefs": [ "ICD9:799.89", "MEDGEN:452939", "NCIT:C93210", "SCTID:128139000", "UMLS:C1290884" ], "synonyms": [ "anatomical structure inflammation", "inflammation of anatomical structure", "inflammatory disease", "inflammatory disorder" ], "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure." }, "child_count": 94, "reference_id": "MONDO:0021166" } ], "children": [ { "id": 4987, "label": "spongiotic dermatitis", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:4406", "ICD9:692.9", "MEDGEN:120468", "NCIT:C27037", "SCTID:23615008", "UMLS:C0262984" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A chronic inflammatory skin condition characterized by itchiness and a rash in the chest and abdominal areas. It affects males more than females and is usually contracted at a relatively young age. It is thought to be caused by an allergic reaction to food, insect bites, or medication." }, "child_count": 0, "reference_id": "MONDO:0002987" }, { "id": 6721, "label": "atopic eczema", "isLeaf": false, "isRoot": false, "parents": [ 4496, 6969 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3310", "EFO:0000274", "HP:0001047", "ICD10CM:L20", "ICD9:691", "ICD9:691.8", "MEDGEN:41502", "MESH:D003876", "NCIT:C3001", "OMIM:603165", "SCTID:200775004", "SCTID:24079001", "UMLS:C0011615", "icd11.foundation:215767047" ], "synonyms": [ "ATOD", "allergic form of dermatitis", "atopic dermatitis", "atopic eczema", "dermatitis, atopic", "eczema", "eczema, atopic", "eczematous dermatitis" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0005046", "name": "immune system disorder" } ], "definition": "A common chronic pruritic inflammatory skin disease with a strong genetic component. Onset typically occurs during the first 2 years of life." }, "child_count": 6, "reference_id": "MONDO:0004980" }, { "id": 6811, "label": "psoriasis", "isLeaf": false, "isRoot": false, "parents": [ 4496, 6778, 23867 ], "type_id": 0, "properties": { "xrefs": [ "DOID:8893", "EFO:0000676", "ICD10CM:L40", "ICD10WHO:L40", "ICD9:696", "ICD9:696.1", "ICD9:696.5", "ICD9:696.8", "MEDGEN:10997", "MESH:D011565", "NCIT:C3346", "OMIMPS:177900", "SCTID:9014002", "UMLS:C0033860", "icd11.foundation:63698555" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0005046", "name": "immune system disorder" } ], "definition": "An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp." }, "child_count": 9, "reference_id": "MONDO:0005083" }, { "id": 7137, "label": "contact dermatitis", "isLeaf": false, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:2773", "EFO:0005319", "ICD9:692.89", "ICD9:692.9", "MEDGEN:8329", "MESH:D003877", "NCIT:C26743", "SCTID:40275004", "UMLS:C0011616" ], "synonyms": [ "contact dermatitis", "contact eczema" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "An inflammatory skin condition caused by direct contact between the skin and either an irritating substance or an allergen." }, "child_count": 4, "reference_id": "MONDO:0005480" }, { "id": 7148, "label": "urticaria", "isLeaf": false, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:1555", "EFO:0005531", "HP:0001025", "ICD10CM:L50", "ICD10WHO:L50", "ICD9:708", "ICD9:708.8", "ICD9:708.9", "MEDGEN:22587", "MESH:D014581", "NCIT:C3432", "SCTID:126485001", "UMLS:C0042109" ], "synonyms": [ "hives", "urticaria", "urticaria (disease)", "Urticarias" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress." }, "child_count": 14, "reference_id": "MONDO:0005492" }, { "id": 8008, "label": "acneiform dermatitis", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:4399", "EFO:1000662", "MEDGEN:68607", "NCIT:C35277", "UMLS:C0234894" ], "synonyms": [ "Rash acneiform" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "Cutaneous eruptions resembling acne, characterized by the presence of papulonodules, pustules, comedones, or cysts in the face, trunk, and extremities. Causes include infections and the use of certain medications (e.g., antibiotics and steroids)." }, "child_count": 0, "reference_id": "MONDO:0006521" }, { "id": 8010, "label": "acrodermatitis", "isLeaf": false, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "CSP:4008-0032", "DOID:2722", "EFO:1000664", "GARD:0027760", "ICD9:686.8", "MEDGEN:1301", "MESH:D000169", "NCIT:C84532", "SCTID:8197001", "UMLS:C0001197" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "An inflammatory skin condition affecting children. It is often associated with Epstein-Barr virus infection, hepatitis B infection or cytomegalovirus infection. It is characterized by the presence of cutaneous rashes and patches on the palms and soles. The trunk is not affected." }, "child_count": 1, "reference_id": "MONDO:0006523" }, { "id": 8035, "label": "folliculitis", "isLeaf": false, "isRoot": false, "parents": [ 4496, 4924 ], "type_id": 0, "properties": { "xrefs": [ "DOID:4409", "EFO:1000702", "ICD9:704.8", "MEDGEN:4752", "MESH:D005499", "NCIT:C94408", "SCTID:13600006", "UMLS:C0016436", "Wikipedia:Folliculitis" ], "synonyms": [ "dermatitis of hair follicle", "hair follicle dermatitis" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "Inflammation of the hair follicles. Causes include excessive perspiration, skin infections, and skin wounds." }, "child_count": 8, "reference_id": "MONDO:0006552" }, { "id": 8037, "label": "granuloma annulare", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3777", "EFO:1000704", "ICD10CM:L92.0", "ICD9:709.8", "MEDGEN:88319", "MESH:D016460", "NCIT:C3470", "SCTID:65508009", "UMLS:C0085074", "Wikipedia:Granuloma_annulare", "icd11.foundation:1925637202" ], "synonyms": [ "granuloma annulare" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "Granuloma annulare is a long-term (chronic) skin disease consisting of a rash with reddish bumps arranged in a circle or ring. The most commonly affected areas are the forearms, hands and feet. The lesions associated with granuloma annulare usually resolve without treatment. Strong steroids (applied as a cream or injection) are sometimes used to clear the rash more quickly. Most symptoms will disappear within 2 years (even without treatment), but recurrence is common. The underlying cause of granuloma annulare is unknown." }, "child_count": 0, "reference_id": "MONDO:0006554" }, { "id": 8038, "label": "granulomatous dermatitis", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:4397", "EFO:1000705", "MEDGEN:196647", "NCIT:C3505", "UMLS:C0743086" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "An inflammatory reaction of the skin to various organic and inorganic antigens. It is characterized by tumor-like masses or nodules of granulomatous tissue comprised of activated histiocytes, epitheliod cells, and multinucleated giant cells." }, "child_count": 0, "reference_id": "MONDO:0006555" }, { "id": 8052, "label": "lichen planus", "isLeaf": false, "isRoot": false, "parents": [ 4496, 8050 ], "type_id": 0, "properties": { "xrefs": [ "DOID:9201", "EFO:1000726", "ICD10CM:L43", "ICD10WHO:L43", "ICD9:697.0", "MEDGEN:9753", "MESH:D008010", "NCIT:C3189", "SCTID:4776004", "UMLS:C0023646", "icd11.foundation:1402978031" ], "synonyms": [ "lichen ruber planus", "ruber planus" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A chronic, recurrent, pruritic inflammatory disorder of unknown etiology that affects the skin and mucus membranes. It presents with rashes and papules that tend to resolve spontaneously. It may be associated with hepatitis C. Certain drugs that contain arsenic or bismuth are associated with reactions mimicking lichen planus." }, "child_count": 22, "reference_id": "MONDO:0006572" }, { "id": 8063, "label": "neurodermatitis", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3309", "EFO:1000740", "ICD10CM:L28.0", "MEDGEN:45056", "MESH:D009450", "NCIT:C111963", "SCTID:267854005", "UMLS:C0027822" ], "synonyms": [ "lichen simplex Chronicus" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "Skin findings arising from repeated rubbing, picking or scratching of a real or imagined irritation of the skin." }, "child_count": 0, "reference_id": "MONDO:0006585" }, { "id": 8064, "label": "neurotic excoriation", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:9165", "ICD9:300.19", "ICD9:698.4", "MEDGEN:697535", "SCTID:402736003", "UMLS:C1274184", "Wikipedia:Neurotic_excoriations" ], "synonyms": [ "dermatitis factitia [artefacta]" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A condition in which patients produce skin lesions through repetitive, compulsive excoriation of their skin." }, "child_count": 0, "reference_id": "MONDO:0006586" }, { "id": 8068, "label": "parapsoriasis", "isLeaf": false, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:9088", "EFO:1000747", "ICD10CM:L41", "ICD10WHO:L41", "ICD9:696.2", "MEDGEN:10579", "MESH:D010267", "NCIT:C3312", "SCTID:88233000", "UMLS:C0030491", "Wikipedia:Parapsoriasis" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "An inflammatory skin disorder of unknown etiology characterized by papules and plaques or scaly patches resembling psoriasis." }, "child_count": 3, "reference_id": "MONDO:0006592" }, { "id": 8076, "label": "pityriasis rosea", "isLeaf": true, "isRoot": false, "parents": [ 4496, 8030 ], "type_id": 0, "properties": { "xrefs": [ "DOID:8892", "EFO:1000756", "ICD10CM:L42", "ICD10WHO:L42", "ICD9:696.3", "MEDGEN:18492", "MESH:D017515", "NCIT:C26855", "SCTID:77252004", "UMLS:C0032026", "Wikipedia:Pityriasis_rosea", "icd11.foundation:919892859" ], "synonyms": [ "Pityriasis circinata", "Pityriasis rosea" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A mild, self-limited skin disorder that is most commonly seen in children and young adults. It is characterized by an initial large round spot on the chest, abdomen, or back, often referred to as a herald patch, that is usually followed within a week by a distinctive pattern of similar but smaller papules on the torso, arms, and legs. There may also be itching, especially when overheated." }, "child_count": 0, "reference_id": "MONDO:0006601" }, { "id": 8083, "label": "seborrheic dermatitis", "isLeaf": false, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:8741", "EFO:1000764", "HP:0001051", "ICD10CM:L21", "ICD9:690.1", "ICD9:690.10", "ICD9:706.3", "MEDGEN:19912", "MESH:D012628", "NCIT:C111888", "UMLS:C0036508" ], "synonyms": [ "cradle Cap", "seborrhea", "seborrheic dermatitis", "seborrheic dermatitis (disease)", "seborrheic eczema", "skin seborrheic" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A chronic, inflammatory skin disorder that affects the scalp, central face and skin folds; it is characterized by scaling and itching." }, "child_count": 1, "reference_id": "MONDO:0006608" }, { "id": 8454, "label": "acanthosis nigricans", "isLeaf": false, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3138", "EFO:1000660", "HP:0000956", "ICD10CM:L83", "ICD10WHO:L83", "MEDGEN:54", "MESH:D000052", "NCIT:C26687", "Orphanet:924", "SCTID:402599005", "UMLS:C0000889", "Wikipedia:Acanthosis_nigricans", "icd11.foundation:71488193" ], "synonyms": [ "acanthosis nigricans", "acanthosis nigricans (disease)", "an - acanthosis nigricans" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A melanotic cutaneous lesion that develops in the axilla and other body folds. It may be idiopathic, drug-induced, or it may be associated with the presence of an endocrine disorder or malignancy." }, "child_count": 2, "reference_id": "MONDO:0007035" }, { "id": 8836, "label": "dermatosis papulosa nigra", "isLeaf": true, "isRoot": false, "parents": [ 4496, 23867 ], "type_id": 0, "properties": { "xrefs": [ "DOID:4400", "EFO:1000686", "ICD9:709.8", "MEDGEN:4238", "MESH:C562379", "NCIT:C2984", "OMIM:125600", "SCTID:254669003", "UMLS:C0011645", "Wikipedia:Dermatosis_papulosa_nigra", "icd11.foundation:168986957" ], "synonyms": [ "dermatosis papulosa nigra", "dermatosis papulosa nigra (morphologic abnormality)" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A benign skin condition commonly seen in dark-skinned individuals that is characterized by multiple small hyperpigmented papular lesions resembling seborrheic keratosis on the face and upper body." }, "child_count": 0, "reference_id": "MONDO:0007446" }, { "id": 9233, "label": "lichen sclerosus et atrophicus", "isLeaf": false, "isRoot": false, "parents": [ 4496, 23867 ], "type_id": 0, "properties": { "xrefs": [ "ICD10CM:L90.0", "MEDGEN:7338", "MESH:D018459", "NCIT:C26817", "OMIM:151590", "Orphanet:33409", "SCTID:25674000", "UMLS:C0023652" ], "synonyms": [ "lichen sclerosus et atrophicus", "LSA", "lichen SCLEROSUS ET ATROPHICUS", "lichen sclerosis", "lichen sclerosis et atrophicus", "lichen sclerosus" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A chronic inflammatory process affecting the skin. It is characterized by the presence of white, indurated plaques, epidermal atrophy, and fibrosis of the upper dermis. It usually appears in the vulva and penis." }, "child_count": 2, "reference_id": "MONDO:0007899" }, { "id": 9939, "label": "vitiligo", "isLeaf": false, "isRoot": false, "parents": [ 4496, 8586 ], "type_id": 0, "properties": { "xrefs": [ "DOID:12306", "EFO:0004208", "ICD10CM:L80", "ICD10WHO:L80", "ICD9:709.01", "MEDGEN:22677", "MESH:D014820", "NCIT:C26915", "Orphanet:247871", "UMLS:C0042900", "icd11.foundation:1894744640" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0005046", "name": "immune system disorder" } ], "definition": "Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes." }, "child_count": 6, "reference_id": "MONDO:0008661" }, { "id": 12543, "label": "acne", "isLeaf": false, "isRoot": false, "parents": [ 4496, 8082, 23867 ], "type_id": 0, "properties": { "xrefs": [ "DOID:6543", "EFO:0003894", "HP:0001061", "ICD10CM:L70", "ICD10WHO:L70", "ICD9:706.0", "MEDGEN:152379", "MTH:217", "NCIT:C27195", "UMLS:C0702166", "icd11.foundation:1892393023" ], "synonyms": [ "acne", "acne (disease)", "acne varioliformis", "acne vulgaris", "acne, adult" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin." }, "child_count": 3, "reference_id": "MONDO:0011438" }, { "id": 16069, "label": "porphyria cutanea tarda", "isLeaf": false, "isRoot": false, "parents": [ 4496, 4591 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3132", "GARD:0007433", "ICD10CM:E80.1", "MEDGEN:56453", "MESH:D017119", "MedDRA:10036183", "NANDO:1200816", "NANDO:2201267", "NCIT:C27725", "ONCOTREE:PCT", "Orphanet:101330", "SCTID:61860000", "UMLS:C0162566", "icd11.foundation:370983230" ], "synonyms": [ "PCT", "porphyria cutania tarda" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005151", "name": "endocrine system disorder" } ], "definition": "The most common form of chronic hepatic porphyria. It is characterized by bullous photodermatitis." }, "child_count": 6, "reference_id": "MONDO:0015104" }, { "id": 16899, "label": "dermatomyositis", "isLeaf": false, "isRoot": false, "parents": [ 4496, 7203, 19007 ], "type_id": 0, "properties": { "xrefs": [ "DOID:10223", "EFO:0000398", "GARD:0006263", "ICD10CM:M33", "ICD9:710.3", "MEDGEN:8331", "MESH:D003882", "MedDRA:10012503", "NANDO:1200274", "NCIT:C26744", "NORD:1048", "Orphanet:221", "SCTID:396230008", "UMLS:C0011633", "icd11.foundation:739030149" ], "synonyms": [ "DM", "dermatomyositis", "dermatopolymyositis", "adult dermatomyositis", "Amyopathic dermatomyositis" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" }, { "ref": "MONDO:0003900", "name": "connective tissue disorder" } ], "definition": "Dermatomyositis (DM) is a type of idiopathic inflammatory myopathy characterized by evocative skin lesions and symmetrical proximal muscle weakness." }, "child_count": 33, "reference_id": "MONDO:0016367" }, { "id": 17693, "label": "acute generalized exanthematous pustulosis", "isLeaf": true, "isRoot": false, "parents": [ 4496, 7238, 17704, 20092 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0021164", "ICD9:709.8", "MEDGEN:209091", "MESH:D056150", "MedDRA:10048799", "NCIT:C112122", "Orphanet:293173", "SCTID:702617007", "UMLS:C0877055" ], "synonyms": [ "AGEP", "pustular drug eruption", "toxic pustuloderma" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A widespread acute rash characterized by fever and multiple small pustules on a reddish background." }, "child_count": 0, "reference_id": "MONDO:0017384" }, { "id": 18198, "label": "hydroa vacciniforme", "isLeaf": false, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0009654", "MEDGEN:5661", "MESH:D006837", "NCIT:C84766", "Orphanet:330058", "SCTID:200837006", "UMLS:C0020241", "icd11.foundation:2053786485" ], "synonyms": [ "hV" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A rare skin disorder of unknown etiology affecting children. It is a photodermatitis, characterized by the formation of vesicles and scarring on sun exposed areas." }, "child_count": 1, "reference_id": "MONDO:0018024" }, { "id": 19177, "label": "autoimmune bullous skin disease", "isLeaf": false, "isRoot": false, "parents": [ 4496, 8092, 8586 ], "type_id": 0, "properties": { "xrefs": [ "DOID:8502", "EFO:0008598", "GARD:0019028", "ICD9:694.8", "ICD9:694.9", "MEDGEN:1842418", "Orphanet:79669", "SCTID:7231009", "UMLS:C5681494" ], "synonyms": [ "bullous skin disease", "bullous dermatosis" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0005046", "name": "immune system disorder" } ], "definition": "An autoimmune disease characterized by blisters on the skin." }, "child_count": 33, "reference_id": "MONDO:0019337" }, { "id": 20014, "label": "cutaneous vasculitis", "isLeaf": false, "isRoot": false, "parents": [ 4496, 18813 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0025172", "MEDGEN:488809", "NCIT:C112210", "UMLS:C0262988" ], "synonyms": [ "cutaneous vasculitis" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0004995", "name": "cardiovascular disorder" } ], "definition": "Inflammation of the blood vessel wall characterized by palpable purpura." }, "child_count": 2, "reference_id": "MONDO:0020576" }, { "id": 20419, "label": "skin infection", "isLeaf": false, "isRoot": false, "parents": [ 4496, 21328 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:52365", "NCIT:C35025", "SCTID:19824006", "UMLS:C0037278" ], "synonyms": [ "skin infection" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "An inflammatory process affecting the skin, caused by bacteria, viruses, parasites, or fungi. Examples of bacterial infection include carbuncles, furuncles, impetigo, erysipelas, and abscesses. Examples of viral infection include shingles, warts, molluscum contagiosum, and pityriasis rosea. Examples of parasitic infection include scabies and lice. Examples of fungal infection include athlete's foot, yeast infection, and ringworm." }, "child_count": 28, "reference_id": "MONDO:0021201" }, { "id": 20514, "label": "intertrigo", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "ICD9:695.89", "MEDGEN:43928", "MESH:D007402", "SCTID:58759008", "UMLS:C0021807" ], "synonyms": [ "Eczema intertrigo", "Erythema intertrigo", "Intertrigo" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A superficial dermatitis occurring on skin surfaces in contact with each other, such as the axillae, neck creases, intergluteal fold, between the toes, etc. Obesity is a predisposing factor. The condition is caused by moisture and friction and is characterized by erythema, maceration, burning, and exudation." }, "child_count": 0, "reference_id": "MONDO:0021340" }, { "id": 21255, "label": "lipodermatosclerosis", "isLeaf": true, "isRoot": false, "parents": [ 4496, 8067, 19369 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0009671", "MEDGEN:140802", "MESH:C537026", "SCTID:410016009", "UMLS:C0406500", "icd11.foundation:473315619" ], "synonyms": [ "acute lipodermatosclerosis", "hypodermitis sclerodermaformis", "sclerosing panniculitis" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0003900", "name": "connective tissue disorder" }, { "ref": "MONDO:0005046", "name": "immune system disorder" } ], "definition": "Lipodermatosclerosis refers to changes in the skin of the lower legs. It is a form of panniculitis (inflammation of the layer of fat under the skin). Signs and symptoms include pain, hardening of skin, change in skin color (redness), swelling, and a tapering of the legs above the ankles. The exact underlying cause is unknown; however, it appears to be associated with venous insufficiency and/or obesity. Treatment usually includes compression therapy." }, "child_count": 0, "reference_id": "MONDO:0023646" }, { "id": 23170, "label": "exfoliative dermatitis", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "EFO:0009456", "ICD10CM:L26", "ICD10WHO:L26", "MEDGEN:3767", "MESH:D003873", "NCIT:C39646", "SCTID:399992009", "UMLS:C0011606" ], "synonyms": [ "exfoliative dermatitis", "Dermatitides, exfoliative", "Erythrodermas", "dermatitis exfoliativa", "erythroderma", "exfoliative Dermatitides" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "The widespread involvement of the skin by a scaly, erythematous dermatitis occurring either as a secondary or reactive process to an underlying cutaneous disorder (e.g., atopic dermatitis, psoriasis, etc.), or as a primary or idiopathic disease. It is often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus. (From Dorland, 27th ed)" }, "child_count": 0, "reference_id": "MONDO:0043233" }, { "id": 23245, "label": "radiodermatitis", "isLeaf": false, "isRoot": false, "parents": [ 4496, 23212 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0025867", "ICD10CM:L58", "ICD10WHO:L58", "MESH:D011855", "NCIT:C3349", "SCTID:49084001" ], "synonyms": [ "dermatitis radiation", "radiation dermatitis", "radiation-induced dermatitis", "radiodermatitis", "Dermatitides, radiation recall", "Dermatitides, radiation-induced", "Radiodermatitides", "dermatitis, radiation induced", "dermatitis, radiation recall", "dermatitis, radiation-induced", "radiation induced dermatitis", "radiation recall Dermatitides", "radiation recall dermatitis", "radiation recall reaction", "radiation recall reactions", "radiation-induced Dermatitides", "reaction, radiation recall", "reactions, radiation recall", "recall reaction, radiation", "recall reactions, radiation" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "A cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation." }, "child_count": 2, "reference_id": "MONDO:0043771" }, { "id": 24230, "label": "food dermatitis", "isLeaf": true, "isRoot": false, "parents": [ 4496 ], "type_id": 0, "properties": { "xrefs": [ "NCIT:C34534" ], "synonyms": [ "dermatitis due to food taken internally" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "Dermatitis caused by an allergic reaction to ingested food." }, "child_count": 0, "reference_id": "MONDO:0100505" } ], "roots": [ { "id": 6820, "label": "skin disorder" }, { "id": 20399, "label": "inflammatory disease" } ] }