{
  "id": 4367,
  "label": "hepatitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002251",
  "properties": {
    "xrefs": [
      "DOID:2237",
      "ICD9:570",
      "ICD9:571.4",
      "ICD9:571.40",
      "ICD9:571.41",
      "MEDGEN:5515",
      "MESH:D006505",
      "NCIT:C3095",
      "SCTID:197268000",
      "UMLS:C0019158"
    ],
    "synonyms": [
      "Hepatitis",
      "hepatitis",
      "inflammation of liver",
      "liver inflammation",
      "acute and subacute liver necrosis",
      "acute hepatitis",
      "acute/subac. necrosis of liver",
      "animal hepatitis",
      "chronic hepatitis",
      "chronic persistent hepatitis",
      "Hepatitides"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An active inflammatory process affecting the liver for more than six months. Causes include viral infections, autoimmune disorders, drugs, and metabolic disorders."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 6878,
      "label": "liver disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4586,
        6875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:409",
          "EFO:0001421",
          "ICD10CM:K70-K77",
          "ICD9:573.8",
          "ICD9:573.9",
          "MEDGEN:893061",
          "MESH:D008107",
          "NCIT:C3196",
          "SCTID:235856003",
          "UMLS:C4021780",
          "icd11.foundation:1784240230"
        ],
        "synonyms": [
          "disease of liver",
          "disease or disorder of liver",
          "disorder of liver",
          "hepatic disease",
          "hepatic disorder",
          "liver and intrahepatic bile duct disorder",
          "liver disease",
          "liver disease or disorder",
          "liver disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the liver."
      },
      "child_count": 64,
      "reference_id": "MONDO:0005154"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 3713,
      "label": "alcoholic hepatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4367,
        23236
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:1754-6978",
          "DOID:12351",
          "EFO:1001345",
          "ICD10CM:K70.1",
          "ICD9:571.1",
          "MEDGEN:42422",
          "MESH:D006519",
          "NCIT:C34684",
          "SCTID:235875008",
          "UMLS:C0019187",
          "icd11.foundation:229221394"
        ],
        "synonyms": [
          "acute alcoholic hepatitis",
          "alcoholic Hepatitis",
          "alcoholic hepatitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Acute hepatitis resulting from ingestion of alcohol."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001505"
    },
    {
      "id": 4307,
      "label": "drug-induced hepatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4367,
        7043
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2044",
          "MEDGEN:226802",
          "SCTID:235889003",
          "UMLS:C1262760"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Liver disease lasting six months or more, caused by an adverse drug effect. The adverse effect may result from a direct toxic effect of a drug or metabolite, or an idiosyncratic response to a drug or metabolite."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002184"
    },
    {
      "id": 4368,
      "label": "granulomatous hepatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4367
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2239",
          "MEDGEN:115987",
          "NCIT:C27015",
          "SCTID:86514004",
          "UMLS:C0235369"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Hepatitis that is characterized by the presence of granulomas."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002252"
    },
    {
      "id": 7405,
      "label": "hepatic tuberculosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2869,
        4367,
        7388,
        8200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:407",
          "EFO:0007302",
          "GARD:0024231",
          "ICD9:017.90",
          "MEDGEN:11944",
          "MESH:D014386",
          "SCTID:186273003",
          "UMLS:C0041313",
          "icd11.foundation:742775377"
        ],
        "synonyms": [
          "tuberculosis of liver"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Infection of the liver with species of mycobacterium, most often mycobacterium tuberculosis. It is characterized by localized small tuberculous miliary lesions or tumor-like mass (tuberculoma), and abnormalities in liver function tests."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005787"
    },
    {
      "id": 7602,
      "label": "viral hepatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4367,
        23208,
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1884",
          "EFO:0004196",
          "ICD10CM:B15-B19",
          "ICD10WHO:B15-B19",
          "ICD9:573.1",
          "MEDGEN:22652",
          "MESH:D006525",
          "NCIT:C35124",
          "SCTID:3738000",
          "UMLS:C0042721",
          "icd11.foundation:985510409"
        ],
        "synonyms": [
          "Hepatitis viral",
          "Viruses caused hepatitis",
          "Viruses hepatitis",
          "viral Hepatitis",
          "viral human hepatitis",
          "unspecified viral hepatitis with hepatic coma",
          "viral hepatitis with hepatic coma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An acute or chronic inflammation of the liver parenchyma caused by viruses. Representative examples include hepatitis A, B, and C, cytomegalovirus hepatitis, and herpes simplex hepatitis."
      },
      "child_count": 18,
      "reference_id": "MONDO:0006011"
    },
    {
      "id": 8446,
      "label": "metabolic dysfunction-associated steatohepatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4367,
        14245
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080547",
          "EFO:1001249",
          "ICD10CM:K75.81",
          "MEDGEN:469032",
          "MedDRA:10053219",
          "NCIT:C84445",
          "UMLS:C3241937",
          "icd11.foundation:1884917970"
        ],
        "synonyms": [
          "MASH",
          "NASH",
          "NASH - nonalcoholic steatohepatitis",
          "non-alcoholic steatohepatitis",
          "nonalcoholic steatohepatitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Metabolic dysfunction-associated steatohepatitis (MASH, formerly known as nonalcoholic steatohepatitis or NASH) is a type of fatty liver disease. It often develops due to a metabolic disorder, such as obesity or diabetes, resulting in a toxic buildup of fat in the liver. It is the most severe form of metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as nonalcoholic fatty liver disease or NAFLD)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007027"
    },
    {
      "id": 16828,
      "label": "autoimmune hepatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2997,
        3002,
        3004,
        4367
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2048",
          "EFO:0005676",
          "GARD:0005871",
          "ICD10CM:K75.4",
          "ICD9:571.42",
          "MEDGEN:1666753",
          "MESH:D019693",
          "MedDRA:10003827",
          "NANDO:1200441",
          "NANDO:1200442",
          "NANDO:2100264",
          "NCIT:C27029",
          "NORD:1897",
          "Orphanet:2137",
          "SCTID:408335007",
          "UMLS:C4721555",
          "icd11.foundation:1235727122"
        ],
        "synonyms": [
          "autoimmune liver disease",
          "autoimmune hepatitis",
          "autoimmune chronic active hepatitis",
          "autoimmune hepatitis with centrilobular necrosis",
          "chronic autoimmune hepatitis",
          "AIH",
          "autoimmune chronic hepatitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Hepatitis caused by autoantibodies. Drugs, infections, and toxins may trigger the production of the autoantibodies against the liver parenchyma."
      },
      "child_count": 28,
      "reference_id": "MONDO:0016264"
    },
    {
      "id": 18266,
      "label": "fulminant viral hepatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4367
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018812",
          "MEDGEN:547442",
          "MedDRA:10019772",
          "Orphanet:35063",
          "UMLS:C0276624",
          "icd11.foundation:369649302"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Fulminant viral hepatitis is a rapid and severe impairment of liver functions (acute liver failure) with hepatic encephalopathy developing less than 8 weeks after the onset of jaundice, secondary to viral hepatitis mainly due to HBV, but also to HAV."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018109"
    },
    {
      "id": 18754,
      "label": "idiopathic peliosis hepatis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4367,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021977",
          "MEDGEN:1814452",
          "Orphanet:480524",
          "UMLS:C5680101"
        ],
        "synonyms": [
          "idiopathic peliosis hepatitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018809"
    }
  ],
  "roots": [
    {
      "id": 6878,
      "label": "liver disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}