{
  "id": 3710,
  "label": "retroperitoneum carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0001502",
  "properties": {
    "xrefs": [
      "DOID:12342",
      "MEDGEN:215301",
      "NCIT:C7352",
      "UMLS:C0948749"
    ],
    "synonyms": [
      "retroperitoneal cancer",
      "carcinoma of retroperitoneal space",
      "carcinoma of retroperitoneum",
      "carcinoma of the retroperitoneum",
      "retroperitoneal carcinoma",
      "retroperitoneal space carcinoma"
    ],
    "definition": "A carcinoma that arises from epithelial cells of the retroperitoneal space."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    },
    {
      "id": 7537,
      "label": "retroperitoneal cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        21554
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5875",
          "EFO:0007466",
          "ICD9:158",
          "ICD9:158.0",
          "MEDGEN:57559",
          "MESH:D012186",
          "NCIT:C3537",
          "SCTID:126872008",
          "UMLS:C0153465",
          "icd11.foundation:1731312506"
        ],
        "synonyms": [
          "neoplasm of retroperitoneum",
          "neoplasm of the retroperitoneum",
          "retroperitoneal neoplasm",
          "tumor of retroperitoneum",
          "tumour of retroperitoneum",
          "cancer of retroperitoneal space",
          "malignant neoplasm of retroperitoneal space",
          "malignant neoplasm of retroperitoneum and peritoneum",
          "malignant retroperitoneal neoplasm",
          "malignant retroperitoneal space neoplasm",
          "malignant tumour of peritoneum and retroperitoneum",
          "retroperitoneal space cancer",
          "malignant neoplasm of retroperitoneum"
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the retroperitoneum. The vast majority of cases are carcinomas, lymphomas, or sarcomas."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005941"
    }
  ],
  "children": [
    {
      "id": 4840,
      "label": "adrenal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3710,
        4843
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3950",
          "GARD:0023252",
          "MESH:D018268"
        ],
        "synonyms": [
          "adrenal gland carcinoma",
          "carcinoma of adrenal gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma involving a adrenal gland."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002814"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    },
    {
      "id": 7537,
      "label": "retroperitoneal cancer"
    }
  ]
}