{
  "id": 3259,
  "label": "prostate squamous cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000993",
  "properties": {
    "xrefs": [
      "DOID:10287",
      "MEDGEN:226996",
      "NCIT:C5536",
      "ONCOTREE:PRSC",
      "SCTID:399590005",
      "UMLS:C1302530"
    ],
    "synonyms": [
      "prostate gland squamous cell carcinoma",
      "prostate squamous cell carcinoma",
      "squamous cell carcinoma of prostate",
      "squamous cell carcinoma of the prostate",
      "PRSC"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "An invasive prostate carcinoma characterized by the presence of squamous differentiation of the malignant cellular infiltrate. There is no evidence of glandular differentiation."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6823,
      "label": "squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4600,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1749",
          "EFO:0000707",
          "ICDO:8070/3",
          "MEDGEN:2874",
          "MESH:D002294",
          "NCIT:C2929",
          "SCTID:402815007",
          "UMLS:C0007137"
        ],
        "synonyms": [
          "carcinoma, squamous cell, malignant",
          "epidermoid carcinoma",
          "epidermoid cell cancer",
          "malignant epidermoid cell neoplasm",
          "malignant epidermoid cell tumor",
          "malignant epidermoid cell tumour",
          "malignant squamous cell neoplasm",
          "malignant squamous cell tumor",
          "malignant squamous cell tumour",
          "squamous carcinoma",
          "squamous cell cancer",
          "squamous cell carcinoma",
          "squamous cell carcinoma (morphologic abnormality)",
          "squamous cell carcinoma NOS (morphologic abnormality)",
          "squamous cell epithelioma"
        ],
        "definition": "A carcinoma arising from squamous epithelial cells. Morphologically, it is characterized by the proliferation of atypical, often pleomorphic squamous cells. Squamous cell carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Well differentiated carcinomas are usually associated with keratin production and the presence of intercellular bridges between adjacent cells. Representative examples are lung squamous cell carcinoma, skin squamous cell carcinoma, and cervical squamous cell carcinoma."
      },
      "child_count": 78,
      "reference_id": "MONDO:0005096"
    },
    {
      "id": 6882,
      "label": "prostate carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        9621
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10286",
          "EFO:0001663",
          "MEDGEN:108657",
          "NCIT:C4863",
          "UMLS:C0600139"
        ],
        "synonyms": [
          "carcinoma of prostate",
          "carcinoma of prostate gland",
          "carcinoma of the prostate",
          "prostate carcinoma",
          "prostate gland carcinoma",
          "cancer of prostate",
          "cancer of the prostate",
          "prostate cancer",
          "prostate cancer, NOS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the prostate gland."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005159"
    }
  ],
  "children": [
    {
      "id": 5461,
      "label": "adenosquamous prostate carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3259,
        7652
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5634",
          "MEDGEN:233353",
          "NCIT:C5538",
          "UMLS:C1335503"
        ],
        "synonyms": [
          "adenosquamous carcinoma of prostate",
          "adenosquamous carcinoma of the prostate",
          "prostate adenosquamous carcinoma",
          "prostate gland adenosquamous carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An infrequent invasive carcinoma of the prostate gland characterized by the presence of both glandular and squamous neoplastic components. It is more often located in the transitional zone of the prostate gland and it tends to rapidly metastasize to the bones."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003558"
    }
  ],
  "roots": [
    {
      "id": 6823,
      "label": "squamous cell carcinoma"
    },
    {
      "id": 6882,
      "label": "prostate carcinoma"
    }
  ]
}