{
  "id": 3033,
  "label": "central nervous system organ benign neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000628",
  "properties": {
    "xrefs": [
      "DOID:0060090",
      "MEDGEN:488882",
      "NCIT:C188049",
      "UMLS:C0347509"
    ],
    "synonyms": [
      "central nervous system benign neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A benign neoplasm that involves the central nervous system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 13,
  "parents": [
    {
      "id": 3049,
      "label": "nervous system benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        20456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060115",
          "ICD9:225.8",
          "ICD9:225.9",
          "MEDGEN:99232",
          "NCIT:C4789",
          "SCTID:92247009",
          "UMLS:C0497550"
        ],
        "synonyms": [
          "benign neoplasm of nervous system",
          "benign neoplasm of the nervous system",
          "benign nervous system neoplasm",
          "benign nervous system tumor",
          "benign nervous system tumour",
          "benign tumor of nervous system",
          "benign tumor of the nervous system",
          "benign tumour of nervous system",
          "benign tumour of the nervous system",
          "nervous system benign neoplasm",
          "nervous system neoplasm, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Abnormal growth of cells in the nervous system without evidence of malignant characteristics. Unlike other organ systems, tumors in the central nervous system can have benign histological characteristics but still have life threatening effects due to their location within the neuraxis (e.g., brainstem gliomas)."
      },
      "child_count": 10,
      "reference_id": "MONDO:0000648"
    },
    {
      "id": 7694,
      "label": "central nervous system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        20456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000158",
          "MEDGEN:88335",
          "NCIT:C9293",
          "UMLS:C0085136"
        ],
        "synonyms": [
          "CNS neoplasm",
          "CNS tumor",
          "CNS tumour",
          "brain/spinal cord tumor",
          "brain/spinal cord tumour",
          "central nervous system neoplasm",
          "central nervous system neoplasm (disease)",
          "central nervous system tumor",
          "central nervous system tumour",
          "neoplasm of CNS",
          "neoplasm of central nervous system",
          "neoplasm of the central nervous system",
          "tumor of CNS",
          "tumor of central nervous system",
          "tumor of the CNS",
          "tumor of the central nervous system",
          "tumour of CNS",
          "tumour of central nervous system",
          "tumour of the CNS",
          "tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm that affects the brain, meninges, or spinal cord. Representative examples of primary neoplasms include astrocytoma, oligodendroglioma, ependymoma, and meningioma. Representative examples of metastatic neoplasms include carcinoma and leukemia."
      },
      "child_count": 20,
      "reference_id": "MONDO:0006130"
    }
  ],
  "children": [
    {
      "id": 4809,
      "label": "central nervous system chondroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3033,
        7940
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3813",
          "MEDGEN:272474",
          "NCIT:C7001",
          "UMLS:C1333019"
        ],
        "synonyms": [
          "CNS chondroma",
          "CNS osteochondroma",
          "central nervous system chondroma",
          "central nervous system osteochondroma",
          "chondroma of CNS",
          "chondroma of central nervous system",
          "chondroma of the CNS",
          "chondroma of the central nervous system",
          "osteochondroma of CNS",
          "osteochondroma of central nervous system",
          "osteochondroma of the CNS",
          "osteochondroma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An extraskeletal chondroma usually arising from the dura."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002779"
    },
    {
      "id": 5188,
      "label": "central nervous system hemangioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        7994,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:501",
          "MEDGEN:272703",
          "NCIT:C7004",
          "UMLS:C1333957"
        ],
        "synonyms": [
          "central nervous system hemangioma",
          "hemangioma of CNS",
          "hemangioma of central nervous system",
          "hemangioma of the CNS",
          "hemangioma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A hemangioma arising from the brain and spinal cord."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003241"
    },
    {
      "id": 5228,
      "label": "central nervous system leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3033,
        3776
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5126",
          "MEDGEN:232695",
          "NCIT:C6998",
          "UMLS:C1334382"
        ],
        "synonyms": [
          "central nervous system leiomyoma",
          "leiomyoma of CNS",
          "leiomyoma of central nervous system",
          "leiomyoma of the CNS",
          "leiomyoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign smooth muscle neoplasm arising from the central nervous system. It is characterized by the presence of intersecting fascicles composed of spindle cells that often lack mitotic activity."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003287"
    },
    {
      "id": 5711,
      "label": "central nervous system lipoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        6833
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6293",
          "MEDGEN:272443",
          "NCIT:C5451",
          "UMLS:C1332885"
        ],
        "synonyms": [
          "CNS lipoma",
          "central nervous system lipoma",
          "lipoma of CNS",
          "lipoma of central nervous system",
          "lipoma of the CNS",
          "lipoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare benign adipose tissue neoplasm of the central nervous system frequently found in midline locations such as the corpus callosum, the quadrigeminal plate, the hypothalamus, the spinal canal or the cauda equina. Some contain Schwann cells, bone, cartilage or hamartomatous blood vessels."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003844"
    },
    {
      "id": 18835,
      "label": "craniopharyngioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        3036,
        4600,
        4759,
        21213,
        22952
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3840",
          "EFO:1000209",
          "GARD:0010486",
          "ICD9:237.0",
          "ICDO:9350/1",
          "MEDGEN:41339",
          "MESH:D003397",
          "MedDRA:10011318",
          "NANDO:2200091",
          "NCIT:C2964",
          "NORD:1996",
          "Orphanet:54595",
          "SCTID:189179009",
          "UMLS:C0010276"
        ],
        "synonyms": [
          "Rathke pouch neoplasm",
          "Rathke pouch tumor",
          "Rathke pouch tumour",
          "Rathke's pouch neoplasm",
          "Rathke's pouch tumor",
          "Rathke's pouch tumour",
          "craniopharyngioma (WHO grade I)",
          "craniopharyngioma (morphologic abnormality)",
          "craniopharyngioma, benign",
          "neoplasm of Rathke's pouch",
          "tumor of Rathke's pouch",
          "tumour of Rathke's pouch",
          "Adamantinomatous tumor",
          "Adamantinomatous tumour",
          "Dysodontogenic epithelial tumor",
          "Dysodontogenic epithelial tumour",
          "craniopharyngeal duct tumor",
          "craniopharyngeal duct tumour",
          "cystoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign, partly cystic, epithelial tumor of the sellar region, presumably derived from Rathke pouch epithelium. It affects mainly children and young adults. There are two clinicopathological forms: adamantinomatous craniopharyngioma and papillary craniopharyngioma. The most significant factor associated with recurrence is the extent of surgical resection, with lesions greater than 5 cm in diameter carrying a markedly worse prognosis. (Adapted from WHO)"
      },
      "child_count": 12,
      "reference_id": "MONDO:0018907"
    },
    {
      "id": 20573,
      "label": "benign neoplasm of brain",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        20429
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000107",
          "ICD9:225.0",
          "MEDGEN:99225",
          "NCIT:C4781",
          "SCTID:92030004",
          "UMLS:C0496899"
        ],
        "synonyms": [
          "benign brain neoplasm",
          "benign brain tumor",
          "benign brain tumour",
          "benign neoplasm of the brain",
          "benign tumor of brain",
          "benign tumor of the brain",
          "benign tumour of brain",
          "benign tumour of the brain",
          "brain benign neoplasm",
          "brain neoplasms, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the brain."
      },
      "child_count": 14,
      "reference_id": "MONDO:0021451"
    },
    {
      "id": 20625,
      "label": "benign neoplasm of spinal cord",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        20444
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:D33.4",
          "ICD9:225.3",
          "MEDGEN:56329",
          "NCIT:C3627",
          "SCTID:92405007",
          "UMLS:C0154034",
          "icd11.foundation:1588169218"
        ],
        "synonyms": [
          "benign neoplasm of the spinal cord",
          "benign spinal cord neoplasm",
          "benign spinal cord tumor",
          "benign spinal cord tumour",
          "benign tumor of spinal cord",
          "benign tumor of the spinal cord",
          "benign tumour of spinal cord",
          "benign tumour of the spinal cord",
          "spinal cord benign neoplasm",
          "spinal cord neoplasm, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the spinal cord."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021506"
    },
    {
      "id": 20644,
      "label": "benign neoplasm of meninges",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        17192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025330",
          "ICD10CM:D32",
          "ICD10WHO:D32",
          "MEDGEN:138093",
          "NCIT:C4957",
          "SCTID:109913001",
          "UMLS:C0348426"
        ],
        "synonyms": [
          "benign meningeal neoplasm",
          "benign meningeal neoplasms",
          "benign meningeal tumor",
          "benign meningeal tumors",
          "benign meningeal tumour",
          "benign meningeal tumours",
          "benign meninges neoplasm",
          "benign meninges tumor",
          "benign meninges tumour",
          "benign neoplasm of the meninges",
          "benign neoplasms of meninges",
          "benign neoplasms of the meninges",
          "benign tumor of meninges",
          "benign tumor of the meninges",
          "benign tumour of meninges",
          "benign tumour of the meninges",
          "meningeal cluster benign neoplasm",
          "meningeal tumors, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the meningeal cluster."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021527"
    },
    {
      "id": 23665,
      "label": "benign neoplasm of peripheral nervous system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        3627
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080320",
          "MEDGEN:199653",
          "UMLS:C0751427"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 16,
      "reference_id": "MONDO:0056804"
    },
    {
      "id": 25255,
      "label": "myxoid glioneuronal tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3033
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081285",
          "MEDGEN:1791986",
          "NCIT:C179229",
          "UMLS:C5555545"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A central nervous system benign neoplasm that is characterized by a dinucleotide mutation at codon 385 of the PDGFR gene. It usually occurs in the septum pellucidum but has also been described in the corpus callosum and periventricular white matter of the lateral ventricle. It is composed of oligodendrocyte-like cells in a prominent myxoid stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0858944"
    },
    {
      "id": 25257,
      "label": "diffuse leptomeningeal glioneuronal tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3033
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081302",
          "MEDGEN:1391318",
          "NCIT:C129424",
          "UMLS:C4329735"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A central nervous system benign neoplasm that is characterized by the presence of clear glial neoplastic cells reminiscent of oligodendroglioma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0858956"
    },
    {
      "id": 25258,
      "label": "multinodular and vacuolating neuronal tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3033
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081303",
          "MEDGEN:1372723",
          "NCIT:C129427",
          "UMLS:C4330721"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A central nervous system benign neoplasm that is composed of cells with glial and/or neuronal differentiation forming multiple nodules with prominent vacuolation and that affecting the cerebral hemispheres."
      },
      "child_count": 0,
      "reference_id": "MONDO:0858957"
    },
    {
      "id": 25260,
      "label": "polymorphous low grade neuroepithelial tumor of the young",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3033
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081305",
          "MEDGEN:1792771",
          "NCIT:C180378",
          "UMLS:C5556330"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A central nervous system benign neoplasm that is characterized by the presence of oligodendroglioma-like components, may also contain astrocytic components and is associated with seizures and in many cases refractory epilepsy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0858959"
    }
  ],
  "roots": [
    {
      "id": 3049,
      "label": "nervous system benign neoplasm"
    },
    {
      "id": 7694,
      "label": "central nervous system neoplasm"
    }
  ]
}