{
  "id": 2955,
  "label": "arteritic anterior ischemic optic neuropathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000498",
  "properties": {
    "xrefs": [
      "DOID:0050863",
      "GARD:0022778",
      "MEDGEN:1378092",
      "SCTID:733506009",
      "UMLS:C2242711",
      "icd11.foundation:815828716"
    ],
    "synonyms": [
      "arteritic aion"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "An anterior ischemic neuropathy that is the cause of vision loss that occurs in temporal arteritis (aka giant cell arteritis)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 8121,
      "label": "anterior ischemic optic neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4268
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12010",
          "EFO:1000809",
          "GARD:0009790",
          "ICD9:377.41",
          "MEDGEN:199716",
          "MESH:D018917",
          "MedDRA:10068250",
          "SCTID:404659001",
          "UMLS:C0751711",
          "icd11.foundation:632323575"
        ],
        "synonyms": [
          "ischaemic optic neuropathy",
          "ischemic optic neuropathy",
          "aion",
          "optic disc infarction leading to vision loss",
          "optic disk infarction leading to vision loss"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Anterior ischemic optic neuropathy (AION) is an eye disease characterized by infarction of the optic disk leading to vision loss. It can be nonarteritic (nonarteritic anterior ischemic optic neuropathy or NAION) or arteritic, the latter being associated with giant cell arteritis (GCA; often termed temporal arteritis). Vision loss with both varieties is typically rapid (over minutes, hours, or days) and painless. Symptoms such as a general feeling of being unwell (malaise), muscle aches and pains, headaches over the temple, pain when combing hair, pain in the jaw after chewing, and tenderness over the temporal artery (one of the major arteries of the head) may be present with giant cell arteritis. At exam, visual acuity is reduced and the optic disk is swollen. In both subtypes, visual field examination is often reduced in the inferior and central visual fields. The visual loss is usually permanent, with some recovery possibly occurring within the first weeks or months. The arteritic variety is treated with corticosteroids. Treatment of the nonarteritic variety withaspirinor corticosteroids has not been helpful."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006649"
    },
    {
      "id": 9828,
      "label": "temporal arteritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4444,
        5281
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13375",
          "EFO:1001209",
          "GARD:0009615",
          "ICD9:446.5",
          "MEDGEN:365495",
          "MedDRA:10018250",
          "MedDRA:10043207",
          "NANDO:1200258",
          "NANDO:1200259",
          "NANDO:1200260",
          "NCIT:C35065",
          "NORD:805",
          "OMIM:187360",
          "Orphanet:397",
          "SCTID:400130008",
          "UMLS:C1956391",
          "icd11.foundation:1929970386"
        ],
        "synonyms": [
          "Giant Cell Arteritis",
          "Horton disease",
          "giant cell arteritis",
          "inflammation of temporal artery",
          "temporal arteritis",
          "temporal artery inflammation",
          "GCA",
          "Horton's arteritis",
          "Horton's giant cell arteritis",
          "Horton's temporal arteritis",
          "Horton’s disease",
          "Horton’s syndrome",
          "arteritis cranialis",
          "arteritis temporalis",
          "cranial arteritis",
          "polymyalgia rheumatica"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries."
      },
      "child_count": 2,
      "reference_id": "MONDO:0008538"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 8121,
      "label": "anterior ischemic optic neuropathy"
    },
    {
      "id": 9828,
      "label": "temporal arteritis"
    }
  ]
}