{
  "id": 9954,
  "label": "Wilms tumor 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008679",
  "properties": {
    "xrefs": [
      "GARD:0015124",
      "OMIM:194070"
    ],
    "synonyms": [
      "Wilms' tumor",
      "Wilms' tumour",
      "renal Wilms tumor",
      "renal Wilms tumour",
      "WT1-related Wilms tumor predisposition",
      "Wilms tumor 1",
      "Wilms tumor type 1",
      "Wilms tumor, autosomal dominant, somatic mutation",
      "Wilms tumor, somatic",
      "Wilms tumor, type 1, autosomal dominant, somatic mutation",
      "Wilms tumour type 1",
      "WT1",
      "nephroblastoma"
    ],
    "definition": "An autosomal disorder due to pathogenic variants in the WT1 gene leading to an increased risk Wilms tumor and genitourinary abnormalities incorporating Denys-Drash syndrome and Frasier syndrome."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5261,
      "label": "hereditary Wilms tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7641
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5183",
          "GARD:0023447",
          "MEDGEN:146190",
          "NCIT:C8496",
          "OMIMPS:194070",
          "UMLS:C0677779"
        ],
        "synonyms": [
          "familial Wilms tumor",
          "familial Wilms tumour",
          "familial Wilms' tumor",
          "familial Wilms' tumour",
          "hereditary Wilms tumor",
          "hereditary kidney adenosarcoma",
          "hereditary nephroblastoma",
          "hereditary renal adenosarcoma",
          "WT1"
        ],
        "definition": "Familial embryonal neoplasm derived from nephrogenic blastemal cells. Several lines of differentiation, including blastemal, stromal and epithelial, are usually expressed. Comprises approximately 1% of Wilms tumors. (AFIP fascicle version 2.0)"
      },
      "child_count": 14,
      "reference_id": "MONDO:0003321"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5261,
      "label": "hereditary Wilms tumor"
    }
  ]
}