{
  "id": 19832,
  "label": "essential iris atrophy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0020371",
  "properties": {
    "xrefs": [
      "GARD:0019611",
      "ICD9:364.51",
      "MEDGEN:543177",
      "NORD:1109",
      "Orphanet:98981",
      "SCTID:25913001",
      "UMLS:C0271111"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "Essential iris atrophy is a clinical variant of iridocorneal endothelial (ICE) syndrome, characterized by progressive iris atrophy and holes present on the surface of the iris, corneal edema, corectopia, uveal ectropion and anterior synechiae. Secondary glaucoma is also a common complication of the disease."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18905,
      "label": "iridocorneal endothelial syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000060",
          "MEDGEN:242751",
          "MESH:D057129",
          "MedDRA:10053678",
          "NCIT:C84792",
          "Orphanet:64734",
          "SCTID:129623003",
          "UMLS:C1096100",
          "icd11.foundation:265074385"
        ],
        "synonyms": [
          "ICE syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Iridocorneal endothelial (ICE) syndrome describes a group of progressive corneal proliferative endotheliopathies comprised of Chandler syndrome, Cogan-Reese syndrome and essential iris atrophy, affecting mainly young adult females and characterized by iris holes and atrophy, papillary distortion, anterior synechiae, corneal edema and often with secondary glaucoma and corneal decompensation as complications"
      },
      "child_count": 3,
      "reference_id": "MONDO:0018988"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18905,
      "label": "iridocorneal endothelial syndrome"
    }
  ]
}