{
  "id": 17417,
  "label": "primary interstitial lung disease specific to childhood",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017015",
  "properties": {
    "xrefs": [
      "GARD:0010559",
      "MEDGEN:853969",
      "Orphanet:264665",
      "UMLS:C3161253",
      "icd11.foundation:1408868257"
    ],
    "synonyms": [
      "primary ILD specific to childhood",
      "primary interstitial lung disease specific to childhood",
      "cHILD",
      "children's interstitial lung disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 17416,
      "label": "interstitial lung disease specific to childhood",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16615
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1842412",
          "Orphanet:264656",
          "SCTID:328661000119108",
          "UMLS:C5679752"
        ],
        "synonyms": [
          "ILD specific to childhood",
          "chILD",
          "chILD syndrome",
          "childhood interstitial lung disease",
          "interstitial lung disease of childhood",
          "paediatric interstitial lung disease",
          "pediatric interstitial lung disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A interstitial lung disease that occurs during childhood."
      },
      "child_count": 5,
      "reference_id": "MONDO:0017014"
    }
  ],
  "children": [
    {
      "id": 11136,
      "label": "alveolar capillary dysplasia with misalignment of pulmonary veins",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17417,
        19778,
        22225,
        24272
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13042",
          "GARD:0008644",
          "ICD9:747.49",
          "ICD9:747.83",
          "MEDGEN:755478",
          "MESH:C536590",
          "MedDRA:10054726",
          "NCIT:C98809",
          "NORD:759",
          "OMIM:265380",
          "Orphanet:210122",
          "SCTID:447275002",
          "UMLS:C2960310"
        ],
        "synonyms": [
          "ACDMPV",
          "alveolar capillary dysplasia",
          "alveolar capillary dysplasia with misalignment of pulmonary veins",
          "alveolar capillary dysplasia with misalignment of pulmonary vessels",
          "congenital alveolar capillary dysplasia",
          "foetal circulation",
          "alveolar capillary dysplasia with misalignment of pulmonary veins and Other congenital anomalies",
          "alveolar capillary dysplasia with misalignment of pulmonary veins and other congenital anomalies",
          "alveolar capillary dysplasia with pulmonary venous misalignment",
          "familial persistent pulmonary hypertension of the newborn",
          "persistent fetal circulation",
          "persistent foetal circulation",
          "persistent foetal circulation syndrome",
          "persistent pulmonary hypertension of the newborn",
          "pulmonary hypertension, familial persistent of the newborn"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare and fatal developmental lung disease characterized by respiratory distress in neonates due to refractory hypoxemia and severe pulmonary arterial hypertension."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009934"
    },
    {
      "id": 12442,
      "label": "congenital chylothorax",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4184,
        17417
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060646",
          "GARD:0010156",
          "ICD9:511.89",
          "MEDGEN:87398",
          "MESH:C535461",
          "OMIM:603523",
          "Orphanet:264688",
          "SCTID:233646003",
          "UMLS:C0340014",
          "icd11.foundation:641475779"
        ],
        "synonyms": [
          "chylothorax, congenital",
          "hydrothorax, congenital"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Congenital chylothorax is a rare, potentially life-threatening neonatal condition characterized by the accumulation of chyle within the pleural space leading to respiratory distress, malnutrition and immunological compromise, either immediately after birth or within the first few weeks of life. Congenital chylothorax is the most common cause of pleural effusion in neonates; it can occur primarily due to developmental anomalies of the lymphatic duct or can be associated with chromosomal anomalies (e.g. Noonan syndrome, Turner syndrome and Down syndrome), hydrops fetalis, mediastinal neuroblastoma and other congenital malformations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011331"
    },
    {
      "id": 13797,
      "label": "lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17417,
        22225,
        23289
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016947",
          "MEDGEN:461506",
          "OMIM:611926",
          "Orphanet:137631",
          "SCTID:721977007",
          "UMLS:C3150156"
        ],
        "synonyms": [
          "immunodeficiency, ovarian dysgenesis, and pulmonary fibrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome is characterized by immune deficiency, gonadal dysgenesis and fatal lung fibrosis. So far, it has been described in two sisters born to consanguineous parents. Both karyotypes were normal female (46,XX). No genetic anomalies could be identified by comparative genome hybridization analysis of their genomes or by analysis of genes known to be associated with these types of anomalies."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012757"
    },
    {
      "id": 17419,
      "label": "interstitial lung disease specific to infancy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17417
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1842984",
          "Orphanet:264694",
          "UMLS:C5679737"
        ],
        "synonyms": [
          "ILD specific to infancy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0017019"
    },
    {
      "id": 24477,
      "label": "newborn respiratory distress syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17417,
        23880
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12716",
          "EFO:1000644",
          "GARD:0026349",
          "ICD10CM:P22.0",
          "ICD9:769",
          "NCIT:C27560",
          "SCTID:46775006"
        ],
        "synonyms": [
          "RDS",
          "respiratory distress syndrome",
          "RDS Of newborns",
          "RDS, respiratory distress syndrome Of newborns",
          "hyaline membrane disease",
          "infant ARDS",
          "infant acute respiratory distress syndrome",
          "infant respiratory distress syndrome",
          "neonatal respiratory distress",
          "neonatal respiratory distress syndrome",
          "newborns (RDS), respiratory distress syndrome Of",
          "respiratory distress syndrome Of newborns",
          "respiratory distress syndrome Of newborns (RDS)",
          "respiratory distress syndrome in the newborn",
          "respiratory distress syndrome of newborn",
          "syndrome Of newborns (RDS), respiratory distress",
          "RDS of prematurity",
          "respiratory distress syndrome in premature infants",
          "NRDS",
          "RDS - infants",
          "respiratory distress syndrome, infant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A condition beginning in the first day of life that results from inadequate surfactant production, causing increased work of breathing and impaired gas exchange."
      },
      "child_count": 2,
      "reference_id": "MONDO:0700081"
    }
  ],
  "roots": [
    {
      "id": 17416,
      "label": "interstitial lung disease specific to childhood"
    }
  ]
}