{
  "id": 7581,
  "label": "toxoplasmosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005989",
  "properties": {
    "xrefs": [
      "DOID:9965",
      "EFO:0007517",
      "ICD10CM:B58",
      "ICD10WHO:B58",
      "ICD9:130",
      "ICD9:130.7",
      "ICD9:130.9",
      "MEDGEN:21597",
      "MESH:D014123",
      "NCIT:C3418",
      "SCTID:187192000",
      "UMLS:C0040558",
      "icd11.foundation:738999268"
    ],
    "synonyms": [
      "Toxoplasma gondii caused disease or disorder",
      "Toxoplasma gondii disease or disorder",
      "Toxoplasma gondii infectious disease"
    ],
    "definition": "A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7336,
      "label": "coccidiosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2113",
          "EFO:0007212",
          "ICD9:007.2",
          "MEDGEN:3138",
          "MESH:D003048",
          "NCIT:C34493",
          "SCTID:62005008",
          "UMLS:C0009187"
        ],
        "synonyms": [
          "coccidiosis (& [intestinal])"
        ],
        "definition": "A parasitic infection caused by Coccidia. It affects livestock, birds and humans. In humans the parasite infests the intestinal tract and may cause watery diarrhea, abdominal pain, fever, nausea and vomiting."
      },
      "child_count": 5,
      "reference_id": "MONDO:0005707"
    }
  ],
  "children": [
    {
      "id": 7328,
      "label": "cerebral toxoplasmosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7581
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10551",
          "EFO:0007200",
          "ICD9:130.0",
          "MEDGEN:38846",
          "MESH:D016781",
          "SCTID:192701001",
          "UMLS:C0085315"
        ],
        "synonyms": [
          "Toxoplasma encephalitis",
          "encephalitis due to acquired toxoplasmosis",
          "meningoencephalitis due to toxoplasmosis"
        ],
        "definition": "Infections of the brain caused by the protozoan toxoplasma gondii that primarily arise in individuals with immunologic deficiency syndromes (see also aids-related opportunistic infections). The infection may involve the brain diffusely or form discrete abscesses. Clinical manifestations include seizures, altered mentation, headache, focal neurologic deficits, and intracranial hypertension. (From Joynt, Clinical Neurology, 1998, Ch27, pp41-3)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0005697"
    },
    {
      "id": 7343,
      "label": "congenital toxoplasmosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4427,
        7581,
        17014,
        21534
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13336",
          "EFO:0007220",
          "GARD:0018708",
          "ICD10CM:P37.1",
          "ICD9:771.2",
          "MEDGEN:52799",
          "MESH:D014125",
          "MedDRA:10010652",
          "NANDO:2200892",
          "NCIT:C50503",
          "Orphanet:858",
          "SCTID:73893000",
          "UMLS:C0040560",
          "icd11.foundation:1194018225"
        ],
        "synonyms": [
          "Toxoplasma embryofetopathy",
          "Toxoplasma embryopathy",
          "congenital toxoplasmosis",
          "mother-to-child transmission of toxoplasmosis",
          "toxoplasmosis, congenital"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Toxoplasma infection that is present from birth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005715"
    },
    {
      "id": 7485,
      "label": "ocular toxoplasmosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7581,
        20247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007399",
          "ICD9:130.7",
          "MEDGEN:21599",
          "MESH:D014126",
          "SCTID:416481006",
          "UMLS:C0040561"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Ocular toxoplasmosis is an infection in the eye caused by the parasite, Toxoplasm a gondii. Toxoplasmosis is the most common cause of eye inflammation in the world. Toxoplamosis can beacquired or present at birth (congenital), having crossed the placenta from a newly infected mother to her fetus. Most humans acquire toxoplasmosis by eating raw or undercooked meat, vegetables or milk products, or by coming into contact with infected cat litterbox or sandboxes.In humans,the infectionusually causes no symptoms, and resolves without treatment in a few months. In individuals with compromised immune systems, Toxoplasm a gondii can reactivate to cause disease. Reactivation of a congenital infection was traditionally thought to be the most common cause ofocular toxoplasmosis, but an acquired infection is now considered to be more common. A toxoplasmosis infection that affects the eye usually attacks the retina andinitially resolves without symptoms. However,the inactive parasite maylaterreactivate causing eyepain, blurred vision, and possibly permanent damage, including blindness. Although most cases of toxoplasmosis resolve on their own,for some,inflammation can be treated with antibiotics and steroids."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005879"
    }
  ],
  "roots": [
    {
      "id": 7336,
      "label": "coccidiosis"
    }
  ]
}