{
  "id": 7352,
  "label": "cryptococcosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005724",
  "properties": {
    "xrefs": [
      "DOID:12053",
      "EFO:0007229",
      "GARD:0006218",
      "ICD10CM:B45",
      "ICD10WHO:B45",
      "ICD9:117.5",
      "MEDGEN:8189",
      "MESH:D003453",
      "MedDRA:10011490",
      "NCIT:C2967",
      "NORD:1019",
      "Orphanet:1546",
      "SCTID:42386007",
      "UMLS:C0010414",
      "icd11.foundation:390527954"
    ],
    "synonyms": [
      "Cryptococcus neoformans caused disease or disorder",
      "Cryptococcus neoformans disease or disorder",
      "Cryptococcus neoformans infectious disease",
      "torulosis"
    ],
    "definition": "An acute or chronic, localized or disseminated infection by Cryptococcus neoformans. Sites of involvement include the lungs, central nervous system and meninges, skin, and visceral organs.--2004"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4420,
      "label": "opportunistic mycosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2473",
          "ICD9:117.9",
          "ICD9:118",
          "MEDGEN:508004",
          "SCTID:78999002",
          "UMLS:C0029119"
        ],
        "synonyms": [
          "opportunistic systemic mycoses"
        ],
        "definition": "A mycosis that arises from infection in an immunologically compromised host."
      },
      "child_count": 12,
      "reference_id": "MONDO:0002312"
    },
    {
      "id": 6859,
      "label": "parasitic infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1398",
          "EFO:0001067",
          "ICD9:129",
          "ICD9:134.8",
          "ICD9:134.9",
          "ICD9:136.4",
          "ICD9:136.8",
          "ICD9:136.9",
          "ICD9:376.13",
          "MEDGEN:45325",
          "MESH:D010272",
          "NCIT:C27864",
          "SCTID:17322007",
          "UMLS:C0030499"
        ],
        "synonyms": [
          "disease caused by parasite",
          "parasitic disease",
          "parasitic infection",
          "ectoparasitic disease",
          "parasitemia",
          "disease, parasitic",
          "diseases, parasitic",
          "infestation",
          "parasite infestation",
          "parasitism",
          "parasitosis"
        ],
        "definition": "A successful invasion of a host by an organism that uses the host for food and shelter."
      },
      "child_count": 17,
      "reference_id": "MONDO:0005135"
    }
  ],
  "children": [
    {
      "id": 7351,
      "label": "Cryptococcal meningitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7352,
        8218
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080159",
          "EFO:0007228",
          "GARD:0024223",
          "ICD9:321.0",
          "MEDGEN:88410",
          "MESH:D016919",
          "NCIT:C174113",
          "SCTID:14232007",
          "UMLS:C0085436"
        ],
        "synonyms": [
          "Cryptococcus neoformans caused infectious meningitis",
          "Cryptococcus neoformans infectious meningitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Meningeal inflammation produced by cryptococcus neoformans, an encapsulated yeast that tends to infect individuals with acquired immunodeficiency syndrome and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature headache; nausea; photophobia; focal neurologic deficits; seizures; cranial neuropathies; and hydrocephalus. (From Adams et al., Principles of Neurology, 6th ed, pp721-2)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0005723"
    }
  ],
  "roots": [
    {
      "id": 4420,
      "label": "opportunistic mycosis"
    },
    {
      "id": 6859,
      "label": "parasitic infectious disease"
    }
  ]
}