{ "id": 6859, "label": "parasitic infectious disease", "model": { "label": "Mondo Disease Ontology (MONDO)", "source": 0 }, "type_id": 0, "reference_id": "MONDO:0005135", "properties": { "xrefs": [ "DOID:1398", "EFO:0001067", "ICD9:129", "ICD9:134.8", "ICD9:134.9", "ICD9:136.4", "ICD9:136.8", "ICD9:136.9", "ICD9:376.13", "MEDGEN:45325", "MESH:D010272", "NCIT:C27864", "SCTID:17322007", "UMLS:C0030499" ], "synonyms": [ "disease caused by parasite", "parasitic disease", "parasitic infection", "ectoparasitic disease", "parasitemia", "disease, parasitic", "diseases, parasitic", "infestation", "parasite infestation", "parasitism", "parasitosis" ], "definition": "A successful invasion of a host by an organism that uses the host for food and shelter." }, "isLeaf": false, "isRoot": false, "child_count": 17, "parents": [ { "id": 7200, "label": "infectious disease", "isLeaf": false, "isRoot": false, "parents": [ 29383 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0050117", "EFO:0005741", "ICD10CM:A00-B99", "ICD9:079.0", "ICD9:136.8", "ICD9:136.9", "IDO:0000436", "MEDGEN:1057", "MESH:D003141", "NCIT:C26726", "SCTID:40733004", "UMLS:C0009450" ], "synonyms": [ "communicable disease", "infection", "infectious", "infectious disease", "infectious diseases and manifestations", "infectious disorder", "transmissible disease", "clinical infection", "disease by infectious agent" ], "definition": "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact." }, "child_count": 35, "reference_id": "MONDO:0005550" } ], "children": [ { "id": 2832, "label": "parasitic Ichthyosporea infectious disease", "isLeaf": false, "isRoot": false, "parents": [ 6859 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0050291" ], "synonyms": [ "Ichthyosporea caused disease or disorder", "Ichthyosporea disease or disorder", "Ichthyosporea infectious disease" ], "definition": "A disease caused by infection with Ichthyosporea." }, "child_count": 1, "reference_id": "MONDO:0000307" }, { "id": 4516, "label": "protozoa infectious disease", "isLeaf": false, "isRoot": false, "parents": [ 6859 ], "type_id": 0, "properties": { "xrefs": [ "DOID:2789", "ICD10CM:B50-B64", "MESH:D011528", "NCIT:C34953" ], "synonyms": [ "protozoal infection", "Mastigophora infectious disease", "sarcomastigophora infectious disease", "parasitic protozoa infectious disease" ], "definition": "An infection that is caused by protozoans." }, "child_count": 15, "reference_id": "MONDO:0002428" }, { "id": 6448, "label": "helminthiasis", "isLeaf": false, "isRoot": false, "parents": [ 6859 ], "type_id": 0, "properties": { "xrefs": [ "DOID:883", "EFO:1001342", "ICD10CM:B65-B83", "ICD9:120-129", "ICD9:128.8", "ICD9:128.9", "MEDGEN:6765", "MESH:D006373", "NCIT:C84751", "SCTID:27601005", "UMLS:C0018889" ], "synonyms": [ "helminthiasis", "worm infection" ], "definition": "A parasitic infection characterized by the infestation with worms, mainly in the intestine." }, "child_count": 22, "reference_id": "MONDO:0004664" }, { "id": 7335, "label": "coccidioidomycosis", "isLeaf": true, "isRoot": false, "parents": [ 2833, 6859 ], "type_id": 0, "properties": { "xrefs": [ "DOID:13450", "EFO:0007211", "GARD:0009525", "ICD10CM:B38", "ICD10WHO:B38", "ICD9:114", "ICD9:114.1", "ICD9:114.9", "MEDGEN:3137", "MESH:D003047", "MedDRA:10009825", "NCIT:C84642", "Orphanet:228123", "SCTID:23247008", "UMLS:C0009186", "icd11.foundation:132287989" ], "synonyms": [ "California disease", "Coccidioides immitis caused disease or disorder", "Coccidioides immitis disease or disorder", "Coccidioides immitis infectious disease", "Coccidioides infection", "San Joaquin valley fever", "Valley fever", "desert fever", "desert rheumatism" ], "definition": "A fungal infection caused by Coccidioides immitis. Affected individuals usually have mild flu-like symptoms. However, pneumonia and systemic involvement with the formation of abscesses may develop as complications of the disease." }, "child_count": 0, "reference_id": "MONDO:0005706" }, { "id": 7352, "label": "cryptococcosis", "isLeaf": false, "isRoot": false, "parents": [ 4420, 6859 ], "type_id": 0, "properties": { "xrefs": [ "DOID:12053", "EFO:0007229", "GARD:0006218", "ICD10CM:B45", "ICD10WHO:B45", "ICD9:117.5", "MEDGEN:8189", "MESH:D003453", "MedDRA:10011490", "NCIT:C2967", "NORD:1019", "Orphanet:1546", "SCTID:42386007", "UMLS:C0010414", "icd11.foundation:390527954" ], "synonyms": [ "Cryptococcus neoformans caused disease or disorder", "Cryptococcus neoformans disease or disorder", "Cryptococcus neoformans infectious disease", "torulosis" ], "definition": "An acute or chronic, localized or disseminated infection by Cryptococcus neoformans. Sites of involvement include the lungs, central nervous system and meninges, skin, and visceral organs.--2004" }, "child_count": 2, "reference_id": "MONDO:0005724" }, { "id": 7458, "label": "microsporidiosis", "isLeaf": false, "isRoot": false, "parents": [ 4420, 6859 ], "type_id": 0, "properties": { "xrefs": [ "DOID:4271", "EFO:0007366", "GARD:0003655", "ICD9:117.9", "MEDGEN:39278", "MESH:D016881", "MedDRA:10053982", "NCIT:C84891", "Orphanet:2552", "SCTID:699676006", "UMLS:C0085407", "icd11.foundation:1021483422" ], "synonyms": [ "Microsporidia caused disease or disorder", "Microsporidia disease or disorder", "Microsporidia infection", "Microsporidia infectious disease", "infection by Microspora", "Microsporidiasis" ], "definition": "A fungal infection caused by Microsporidia. It occurs in immunocompromised patients, causing diarrhea and wasting." }, "child_count": 2, "reference_id": "MONDO:0005846" }, { "id": 7565, "label": "Strongylida infectious disease", "isLeaf": true, "isRoot": false, "parents": [ 6859 ], "type_id": 0, "properties": { "xrefs": [ "MESH:D017206" ], "definition": "Infections with nematodes of the order strongylida." }, "child_count": 0, "reference_id": "MONDO:0005973" }, { "id": 16447, "label": "distomatosis", "isLeaf": true, "isRoot": false, "parents": [ 6859 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0001891", "ICD9:121.8", "ICD9:121.9", "MEDGEN:21251", "Orphanet:1685", "SCTID:26089000", "UMLS:C0040820" ], "synonyms": [ "distomiasis", "fluke infection" ], "definition": "Distomatosis is a group of parasitoses caused by flat worms that live in contact with epitheliums. Clinical classification depends on the organ infected by the adult parasite: liver, lungs, or intestines." }, "child_count": 0, "reference_id": "MONDO:0015675" }, { "id": 16741, "label": "parasitic myositis", "isLeaf": false, "isRoot": false, "parents": [ 6859, 21219 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0020379", "ICD9:728.2", "MEDGEN:538249", "Orphanet:206997", "SCTID:60970005", "UMLS:C0263997", "icd11.foundation:110646208" ], "categories": [ { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" } ] }, "child_count": 2, "reference_id": "MONDO:0016128" }, { "id": 17604, "label": "demodicidosis", "isLeaf": false, "isRoot": false, "parents": [ 4198, 6859 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0001802", "MEDGEN:581217", "Orphanet:283", "UMLS:C0392666", "icd11.foundation:1473144548" ], "synonyms": [ "Demodex caused disease or disorder", "Demodex disease or disorder", "Demodex infectious disease", "Demodicosis", "demodectic mange", "red mange" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "Demodicidosis is a rare parasitic cutaneous disease due to Demodex mite infestation characterized by variable degrees of spinulosis, erythema, papules, and pustules, usually accompanied by a burning or pruritic sensation. Face (incl. eyelids) is most frequently affected, but ear canal, scalp, neck, back, chest, nipples, buttocks, penis, and extremity (legs and arms) involvement have also been observed. Dermoscopic examination reveals Demodex tails and follicular openings." }, "child_count": 4, "reference_id": "MONDO:0017280" }, { "id": 18535, "label": "cutaneous larva migrans", "isLeaf": false, "isRoot": false, "parents": [ 6859 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0001629", "ICD9:126.9", "MEDGEN:107487", "MESH:D007815", "Orphanet:423717", "SCTID:19362000", "UMLS:C0546999", "icd11.foundation:657025682" ], "synonyms": [ "CLM", "creeping eruption", "dew itch", "ground itch" ], "definition": "Cutaneous larva migrans is a rare parasitic disease characterized by single or multiple, linear or serpinginous, erythematous, slightly elevated cutaneous tracks caused by the larval migration of various nematode species. Tracks are variable in length, generally a few millimeters wide and are frequently located on the feet (although any area of the body is possible). Patients typically present with severe, intractable pruritus, which, in some cases, may cause impaired concentration, loss of sleep, and mood disturbances." }, "child_count": 1, "reference_id": "MONDO:0018500" }, { "id": 18941, "label": "amoebiasis due to Entamoeba histolytica", "isLeaf": true, "isRoot": false, "parents": [ 6859 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0018675", "MEDGEN:443898", "MESH:C531613", "Orphanet:67", "UMLS:C2930799" ], "definition": "A parasitic disease caused by the protozoa, Entamoeba histolytica, mainly occurring in tropical regions after the ingestion of an amoebic cyst, and resulting in clinical manifestations that may range from an asymptomatic state to amoebic colitis (violent abdominal pain, a painful contracted feeling around the anal sphincter, blood and mucus in the stools but without the presence of fever), or amoebic liver abscesses (fever, chills, abdominal pain, weight loss, hepatomegaly) that can be fatal if not immediately treated. Extraintestinal involvement elsewhere (i.e. thoracic, hepatic) is extremely rare." }, "child_count": 0, "reference_id": "MONDO:0019028" }, { "id": 18948, "label": "amoebiasis due to free-living amoebae", "isLeaf": true, "isRoot": false, "parents": [ 6859 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0012650", "MEDGEN:509253", "Orphanet:68", "UMLS:C0153326" ], "definition": "Free-living amebae belonging to the genera Acanthamoeba, Balamuthia, Naegleria and Sappinia are important causes of disease in humans and animals. Naegleria fowleri produces an acute, and usually lethal, central nervous system (CNS) disease called primary amebic meningoencephalitis (PAM). Acanthamoeba spp. and Balamuthia mandrillaris are opportunistic free-living amebae capable of causing granulomatous amebic encephalitis (GAE) in individuals with compromised immune systems. Sappinia pedata has been implicated in a case of amebic encephalitis. Naegleria fowleri and Acanthamoeba spp., are commonly found in lakes, swimming pools, tap water, and heating and air conditioning units." }, "child_count": 0, "reference_id": "MONDO:0019036" }, { "id": 20247, "label": "parasitic eye infection", "isLeaf": false, "isRoot": false, "parents": [ 6859, 23257 ], "type_id": 0, "properties": { "xrefs": [ "ICD9:136.9", "MEDGEN:8752", "MESH:D015822", "SCTID:312418006", "UMLS:C0015406" ], "synonyms": [ "parasitic eye infection", "EYE INFECT PARASITIC", "Eye Infection, Parasitic", "Eye Infections, Parasitic", "Infection, Parasitic Eye", "Infection, Parasitic Ocular", "Infections, Parasitic Eye", "Infections, Parasitic Ocular", "OCULAR INFECT PARASITIC", "Ocular Infection, Parasitic", "Ocular Infections, Parasitic", "PARASITIC EYE INFECT", "Parasitic Eye Infection", "Parasitic Eye Infections", "Parasitic Ocular Infection", "Parasitic Ocular Infections", "Parasitic eye infection" ], "categories": [ { "ref": "MONDO:0002022", "name": "disorder of orbital region" }, { "ref": "MONDO:0024458", "name": "disorder of visual system" } ], "definition": "Mild to severe infections of the eye and its adjacent structures (adnexa) by adult or larval protozoan or metazoan parasites." }, "child_count": 10, "reference_id": "MONDO:0020947" }, { "id": 21309, "label": "parasitic intestinal disorder", "isLeaf": false, "isRoot": false, "parents": [ 6756, 6859, 23208 ], "type_id": 0, "properties": { "xrefs": [ "EFO:0009561", "MEDGEN:7131", "MESH:D007411", "UMLS:C0021832" ], "synonyms": [ "intestine parasitic infection", "parasitic intestinal disease", "disease, parasitic intestinal", "diseases, parasitic intestinal", "intestinal disease, parasitic", "parasitic intestinal diseases" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS." }, "child_count": 21, "reference_id": "MONDO:0024270" }, { "id": 21347, "label": "parasitemia", "isLeaf": true, "isRoot": false, "parents": [ 6859, 7217 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:116650", "MESH:D018512", "UMLS:C0242723" ], "synonyms": [ "Parasitemias" ], "categories": [ { "ref": "MONDO:0005570", "name": "hematologic disorder" } ], "definition": "The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)" }, "child_count": 0, "reference_id": "MONDO:0024314" }, { "id": 21525, "label": "parasitic skin disorder", "isLeaf": false, "isRoot": false, "parents": [ 6859, 21328 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:20780", "MESH:D012876", "UMLS:C0037280" ], "synonyms": [ "parasitic skin disease", "disease, parasitic skin", "diseases, parasitic skin", "parasitic skin diseases", "skin disease, parasitic" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" } ], "definition": "Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites." }, "child_count": 12, "reference_id": "MONDO:0024610" } ], "roots": [ { "id": 7200, "label": "infectious disease" } ] }