{
  "id": 2838,
  "label": "commensal bacterial infectious disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0000315",
  "properties": {
    "xrefs": [
      "DOID:0050339"
    ],
    "synonyms": [
      "opportunistic bacterial infectious disease"
    ],
    "definition": "A bacterial infectious disease that results in infection by bacteria which are part of the normal human flora when one or more of the defense mechanisms designed to restrict them from the usually sterile internal tissues are breached by accident, by intent (surgery), or by an underlying metabolic or an infectious disorder."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 6839,
      "label": "bacterial infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:104",
          "EFO:0000771",
          "ICD9:040.89",
          "ICD9:041.89",
          "ICD9:041.9",
          "MEDGEN:14012",
          "MESH:D001424",
          "NCIT:C2890",
          "SCTID:87628006",
          "UMLS:C0004623"
        ],
        "synonyms": [
          "Bacteria caused disease or disorder",
          "Bacteria disease or disorder",
          "Bacteria infectious disease",
          "bacterial disease",
          "bacterial disorder",
          "bacterial infection",
          "bacterial infectious disease",
          "infection, bacterial",
          "infections, bacterial"
        ],
        "definition": "An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections."
      },
      "child_count": 52,
      "reference_id": "MONDO:0005113"
    }
  ],
  "children": [
    {
      "id": 4056,
      "label": "toxic shock syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2838,
        4370
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14115",
          "GARD:0009560",
          "ICD10CM:A48.3",
          "ICD9:040.82",
          "MEDGEN:109414",
          "MESH:D012772",
          "NCIT:C35498",
          "NORD:1782",
          "Orphanet:36234",
          "SCTID:18504008",
          "UMLS:C0600327",
          "icd11.foundation:114886962"
        ],
        "synonyms": [
          "TSS",
          "TSS, toxic shock syndrome",
          "bacterial TSS",
          "bacterial toxic-shock syndrome",
          "shock syndrome (TSS), toxic",
          "syndrome (TSS), toxic shock",
          "toxic shock syndrome",
          "toxic shock syndrome, (TSS)",
          "staphylococcal toxic shock syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A rare acute life-threatening systemic bacterial noncontagious illness caused by exotoxins from bacteria of either the Streptococcus pyogenes or Staphylococcus aureus type. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001881"
    },
    {
      "id": 7270,
      "label": "actinomycosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2838,
        8354
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8478",
          "EFO:0007128",
          "GARD:0005728",
          "ICD10CM:A42",
          "ICD10WHO:A42",
          "ICD9:039",
          "MEDGEN:1733",
          "MESH:D000196",
          "NCIT:C34350",
          "Orphanet:457095",
          "UMLS:C0001261",
          "icd11.foundation:1697630330"
        ],
        "synonyms": [
          "Actinomyces infection",
          "Actinomyces israeli",
          "Actinomycetes",
          "Keratoactinomycosis",
          "anaerobic Actinomyces infection",
          "boil",
          "canaliculitis",
          "infections, Actinomyces"
        ],
        "definition": "Actinomycosis is a chronic bacterial infection that commonly affects the face and neck. It is usually caused by an anaerobic bacteria called Actinomyces israelii. Actinomyces are normal inhabitants of the mouth, gastrointestinal tract, and female genital tract, and do not cause an infection unless there is a break in the skin or mucosa. The infection usually occurs in the face and neck, but can sometimes occur in the chest, abdomen, pelvis, or other areas of the body. The infection is not contagious."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005631"
    },
    {
      "id": 7332,
      "label": "chlamydia trachomatis infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2838,
        20728
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11263",
          "EFO:0007205",
          "ICD9:078.88",
          "ICD9:079.88",
          "ICD9:079.98",
          "NCIT:C34463",
          "SCTID:105629000"
        ],
        "synonyms": [
          "Chlamydia trachomatis caused disease or disorder",
          "Chlamydia trachomatis disease or disorder",
          "Chlamydial infection",
          "chlamydia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An infection that is caused by Chlamydia trachomatis."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005701"
    },
    {
      "id": 7387,
      "label": "gas gangrene",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2838,
        6940,
        8092,
        21153,
        21329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9159",
          "EFO:0007279",
          "GARD:0024229",
          "ICD10CM:A48.0",
          "ICD9:040.0",
          "MEDGEN:8959",
          "MESH:D005738",
          "SCTID:80466000",
          "UMLS:C0017105",
          "icd11.foundation:1920227791"
        ],
        "synonyms": [
          "gas gangrene",
          "myonecrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A severe condition resulting from bacteria invading healthy muscle from adjacent traumatized muscle or soft tissue. The infection originates in a wound contaminated with bacteria of the genus clostridium. C. perfringens accounts for the majority of cases (over eighty percent), while C. noyvi, C. septicum, and C. histolyticum cause most of the other cases."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005767"
    },
    {
      "id": 16185,
      "label": "Lemierre syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2838,
        6940
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11337",
          "GARD:0006882",
          "ICD9:040.3",
          "MEDGEN:6541",
          "MESH:D057831",
          "MedDRA:10065552",
          "Orphanet:137839",
          "SCTID:52542005",
          "UMLS:C0027537"
        ],
        "synonyms": [
          "Lemierre postanginal sepsis",
          "Lemierre syndrome",
          "postanginal sepsis secondary to orophyngeal infection",
          "septic phlebitis of the internal jugular vein",
          "Lemierre's syndrome",
          "necrobacillosis",
          "oropharyngeal infection leading to secondary septic thrombophlebitis of the internal jugular vein"
        ],
        "definition": "Lemierre syndrome is a rare, potentially lethal, oropharyngeal infectious disease occurring in immunocompetent adolescents and young adults that is mainly due to Fusobacterium necrophorum and that is characterized by septic thrombophlebitis of the internal jugular vein that leads to septic, usually pulmonary, embolism, associated with ENT (ear, nose, and throat) infection that manifests with fever, neck pain, and tonsillopharyngitis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015306"
    },
    {
      "id": 18323,
      "label": "staphylococcal scalded skin syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2838,
        7197,
        17872,
        21329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9063",
          "EFO:0007473",
          "GARD:0013158",
          "ICD10CM:L00",
          "ICD10WHO:L00",
          "ICD9:695.81",
          "MEDGEN:52484",
          "MESH:D013206",
          "MedDRA:10041929",
          "NCIT:C85077",
          "NORD:1781",
          "Orphanet:36236",
          "SCTID:200946001",
          "SCTID:277475006",
          "UMLS:C0038165",
          "icd11.foundation:1554593739"
        ],
        "synonyms": [
          "Ritter disease",
          "Ritter's disease",
          "SSSS",
          "generalised exfoliative disease",
          "generalized exfoliative disease",
          "staphylococcal scalded skin syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A blistering skin disorder caused by exfoliative toxins produced by Staphylococcus aureus infection. The toxins cause the formation of bullae and diffuse skin desquamation. The lesions may be localized or generalized, far away from the initial site of infection."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018181"
    }
  ],
  "roots": [
    {
      "id": 6839,
      "label": "bacterial infectious disease"
    }
  ]
}