{
  "id": 22963,
  "label": "ovarian serous tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0037255",
  "properties": {
    "xrefs": [
      "MEDGEN:141653",
      "NCIT:C8431",
      "UMLS:C0476122"
    ],
    "synonyms": [
      "ovarian serous neoplasm",
      "ovarian serous tumor",
      "serous neoplasm of ovary",
      "serous neoplasm of the ovary",
      "serous tumor of ovary",
      "serous tumor of the ovary",
      "serous tumour of ovary",
      "serous tumour of the ovary"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A benign, borderline, or malignant epithelial tumor of the ovary characterized by the presence of neoplastic epithelial cells that, in well differentiated tumors, resemble the epithelial cells of the fallopian tube and, in poorly differentiated tumors, show anaplastic features. Approximately thirty to fifty percent of the tumors are bilateral. Grossly, the better differentiated tumors consist of cystic masses, usually unilocular, containing a clear but sometimes viscous fluid. Papillary formations are often present. The more malignant tumors tend to be solid and invasive, with areas of necrosis and hemorrhage."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4347,
      "label": "ovarian epithelial tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265,
        20309
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2152",
          "ICD9:239.5",
          "MEDGEN:90969",
          "NCIT:C4381",
          "ONCOTREE:OVT",
          "SCTID:237057005",
          "UMLS:C0341823"
        ],
        "synonyms": [
          "epithelial neoplasm of ovary",
          "epithelial neoplasm of the ovary",
          "epithelial tumor of ovary",
          "epithelial tumor of the ovary",
          "epithelial tumour of ovary",
          "epithelial tumour of the ovary",
          "ovarian epithelial tumor",
          "ovarian surface epithelial-stromal tumor",
          "ovarian surface epithelial-stromal tumour",
          "ovarian surface-epithelial stromal neoplasm",
          "ovary epithelial neoplasm",
          "OVT",
          "ovary epithelial cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant tumor that originates from the surface epithelium of the ovary. It is composed of epithelial cells and stroma. Representative examples of benign tumors include serous cystadenoma, mucinous cystadenoma, and benign Brenner tumor. Representative examples of borderline tumors include serous surface papillary tumor, mucinous adenofibroma, and borderline Brenner tumor. Representative examples of malignant tumors include serous adenocarcinoma, mucinous adenocarcinoma, endometrioid adenocarcinoma, and malignant Brenner tumor."
      },
      "child_count": 22,
      "reference_id": "MONDO:0002229"
    },
    {
      "id": 22964,
      "label": "serous neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:233442",
          "NCIT:C7074",
          "UMLS:C1335951"
        ],
        "synonyms": [
          "serous neoplasm"
        ]
      },
      "child_count": 1,
      "reference_id": "MONDO:0037256"
    }
  ],
  "children": [
    {
      "id": 20075,
      "label": "borderline ovarian serous tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16720,
        22963
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000139",
          "GARD:0025205",
          "MEDGEN:231957",
          "NCIT:C5226",
          "UMLS:C1332598"
        ],
        "synonyms": [
          "borderline ovarian serous neoplasm",
          "borderline ovarian serous tumor",
          "borderline serous neoplasm of ovary",
          "borderline serous neoplasm of the ovary",
          "borderline serous tumor of ovary",
          "borderline serous tumor of the ovary",
          "borderline serous tumour of ovary",
          "borderline serous tumour of the ovary",
          "ovarian serous neoplasm of low malignant potential",
          "ovarian serous tumor of low malignant potential",
          "ovarian serous tumour of low malignant potential",
          "proliferating ovarian serous neoplasm",
          "proliferating ovarian serous tumor",
          "proliferating ovarian serous tumour",
          "proliferating serous neoplasm of ovary",
          "proliferating serous neoplasm of the ovary",
          "proliferating serous tumor of ovary",
          "proliferating serous tumor of the ovary",
          "proliferating serous tumour of ovary",
          "proliferating serous tumour of the ovary",
          "serous neoplasm of ovary with low malignant potential",
          "serous neoplasm of the ovary with low malignant potential",
          "serous ovarian neoplasm of low malignant potential",
          "serous ovarian tumor of low malignant potential",
          "serous ovarian tumour of low malignant potential",
          "serous tumor of ovary with low malignant potential",
          "serous tumor of the ovary with low malignant potential",
          "serous tumour of ovary with low malignant potential",
          "serous tumour of the ovary with low malignant potential"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A low grade serous epithelial neoplasm arising from the ovary. It is characterized by an atypical proliferation of serous-type epithelial cells without evidence of stromal invasion. It is often asymptomatic but rarely it may present with abdominal pain or abdominal enlargement due to rupture or torsion."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020662"
    },
    {
      "id": 21609,
      "label": "malignant ovarian serous tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18447,
        22963
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025472",
          "MEDGEN:309396",
          "NCIT:C40025",
          "UMLS:C1518234"
        ],
        "synonyms": [
          "malignant ovarian serous tumor",
          "ovarian serous tumor, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An invasive malignant neoplasm that arises from the ovary and is characterized by the presence of malignant epithelial cells that, in well differentiated tumors, resemble the epithelium of the fallopian tube or, in poorly differentiated tumors, show anaplastic features and marked nuclear atypia. It includes serous adenocarcinoma and serous adenocarcinofibroma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024885"
    }
  ],
  "roots": [
    {
      "id": 4347,
      "label": "ovarian epithelial tumor"
    },
    {
      "id": 22964,
      "label": "serous neoplasm"
    }
  ]
}