{
  "id": 17200,
  "label": "benign peripheral nerve sheath tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016752",
  "properties": {
    "xrefs": [
      "GARD:0007180",
      "MEDGEN:1843306",
      "Orphanet:252131",
      "UMLS:C5577926"
    ],
    "synonyms": [
      "BPNST"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 17197,
      "label": "tumor of cranial and spinal nerves",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012697",
          "MEDGEN:1842705",
          "Orphanet:252057",
          "UMLS:C5679636"
        ],
        "synonyms": [
          "rare tumor of cranial and spinal nerves",
          "rare tumour of cranial and spinal nerves"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0016749"
    }
  ],
  "children": [
    {
      "id": 4612,
      "label": "schwannoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4613,
        17200,
        20693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3192",
          "DOID:955",
          "EFO:0000693",
          "GARD:0004767",
          "ICD9:215.9",
          "ICDO:9560/0",
          "MEDGEN:45053",
          "MedDRA:10029234",
          "MedDRA:10029235",
          "NANDO:2200103",
          "NCIT:C3269",
          "ONCOTREE:SCHW",
          "Orphanet:252164",
          "SCTID:404022001",
          "UMLS:C0027809",
          "icd11.foundation:378766741"
        ],
        "synonyms": [
          "benign neurilemmoma",
          "benign schwannoma",
          "neurilemmoma",
          "neurinoma",
          "peripheral fibroblastoma",
          "schwannoma",
          "schwannoma (WHO grade I)",
          "schwannoma, benign",
          "SCHW",
          "neurolemmoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign, usually encapsulated slow growing tumor composed of Schwann cells. It affects peripheral and cranial nerves. It recurs infrequently and only rare cases associated with malignant transformation have been reported."
      },
      "child_count": 30,
      "reference_id": "MONDO:0002546"
    },
    {
      "id": 17201,
      "label": "neurofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4613,
        17200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:962",
          "GARD:0007191",
          "ICD9:215.9",
          "ICDO:9540/0",
          "MEDGEN:45058",
          "MESH:D009455",
          "MedDRA:10029267",
          "NCIT:C3272",
          "ONCOTREE:NFIB",
          "Orphanet:252183",
          "SCTID:404029005",
          "UMLS:C0027830",
          "icd11.foundation:221014277"
        ],
        "synonyms": [
          "neurofibroma",
          "neurofibroma (WHO grade I)",
          "neurofibroma, benign",
          "NFIB"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An intraneural or extraneural neoplasm arising from nerve tissues and neural sheaths. It is composed of perineurial-like fibroblasts and Schwann cells. It usually presents as a localized cutaneous lesion and less often as a circumscribed peripheral nerve mass. Patients with neurofibromatosis type 1 present with multiple masses. Neurofibromas which arise from major nerves and plexiform neurofibromas are precursor lesions to malignant peripheral nerve sheath tumors."
      },
      "child_count": 22,
      "reference_id": "MONDO:0016755"
    },
    {
      "id": 17865,
      "label": "painful orbital and systemic neurofibromas-marfanoid habitus syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0011006",
          "MEDGEN:1650687",
          "Orphanet:300501",
          "UMLS:C4751109"
        ],
        "synonyms": [
          "multiple orbital neurofibromas, painful peripheral nerve tumors, distinctive face and marfanoid habitus"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017585"
    }
  ],
  "roots": [
    {
      "id": 17197,
      "label": "tumor of cranial and spinal nerves"
    }
  ]
}