{
  "id": 17186,
  "label": "anaplastic ganglioglioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016734",
  "properties": {
    "xrefs": [
      "GARD:0010639",
      "ICDO:9505/3",
      "MEDGEN:140906",
      "NCIT:C4717",
      "ONCOTREE:AGNG",
      "Orphanet:251957",
      "UMLS:C0431112"
    ],
    "synonyms": [
      "AGNG"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A WHO grade III neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and anaplastic glial cells. The anaplastic changes in the glial component and high MIB-1 and TP53 labeling indices may indicate aggressive behavior. However, the correlation of histological anaplasia with clinical outcome is inconsistent. (Adapted from WHO)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17185,
      "label": "ganglioglioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17182
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5078",
          "EFO:0003094",
          "GARD:0002430",
          "ICDO:9505/1",
          "MEDGEN:60216",
          "MESH:D018303",
          "MedDRA:10017701",
          "NANDO:2200096",
          "NCIT:C3788",
          "ONCOTREE:GNG",
          "Orphanet:251949",
          "SCTID:87191000119100",
          "UMLS:C0206716",
          "icd11.foundation:1287417975"
        ],
        "synonyms": [
          "ganglioglioma",
          "adult ganglioglioma",
          "childhood ganglioglioma",
          "mixed cell tumors containing both neural ganglionic cells and neural glial cell components",
          "mixed cell tumours containing both neural ganglionic cells and neural glial cell components"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A well differentiated, slow growing neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and neoplastic glial cells. Some gangliogliomas show anaplastic features in their glial component and are considered to be WHO grade III. Rare cases of newly diagnosed gangliogliomas with grade IV (glioblastoma) changes in the glial component have also been reported. (Adapted from WHO)"
      },
      "child_count": 2,
      "reference_id": "MONDO:0016733"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17185,
      "label": "ganglioglioma"
    }
  ]
}