{
  "id": 17184,
  "label": "desmoplastic infantile astrocytoma/ganglioglioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016731",
  "properties": {
    "xrefs": [
      "GARD:0020729",
      "MEDGEN:1665232",
      "Orphanet:251940",
      "UMLS:C4757951"
    ],
    "synonyms": [
      "DIA/DIG"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Desmoplastic infantile astrocytoma/ganglioglioma are mixed neuronal-glial tumors representing a histological spectrum of the same tumor. They are usually supratentorially located, large, cystic masses with a peripheral solid component, characterized by prominent desmoplastic stroma and pleomorphic populations of neoplastic cells with either astrocytic or ganglionic differentiation and poorly differentiated cells in variable proportions. They usually present in the first 18 months of age with rapid head growth, bulging anterior fontanel and bone structures over the tumor, signs of raised intracranial pressure (headache, vomiting, papilledema), focal neurological signs and sometimes seizures."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17182,
      "label": "mixed neuronal-glial tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20418
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020728",
          "MEDGEN:105377",
          "NCIT:C4747",
          "Orphanet:251934",
          "UMLS:C0474844",
          "icd11.foundation:1792897751"
        ],
        "synonyms": [
          "neuronal and Glio-neuronal neoplasm",
          "neuronal and Glio-neuronal tumor",
          "neuronal and Glio-neuronal tumour",
          "neuronal and mixed neuronal-glial tumor",
          "neuronal and mixed neuronal-glial tumors",
          "neuronal and mixed neuronal-glial tumour",
          "neuronal and mixed neuronal-glial tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of central nervous system neoplasms with a variable amount of neuronal and, less consistently, glial differentiation. They occur at a low frequency and usually carry a favorable prognosis. Representative examples include dysplastic cerebellar gangliocytoma, desmoplastic infantile ganglioglioma, desmoplastic infantile astrocytoma, and dysembryoplastic neuroepithelial tumor. (Adapted from WHO)"
      },
      "child_count": 12,
      "reference_id": "MONDO:0016729"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17182,
      "label": "mixed neuronal-glial tumor"
    }
  ]
}