{
  "id": 12860,
  "label": "CINCA syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0011776",
  "properties": {
    "xrefs": [
      "DOID:0090029",
      "GARD:0001356",
      "ICD9:759.89",
      "MEDGEN:98370",
      "NANDO:1200468",
      "NANDO:2201066",
      "NCIT:C116380",
      "NORD:1496",
      "OMIM:607115",
      "Orphanet:1451",
      "SCTID:239826001",
      "UMLS:C0409818"
    ],
    "synonyms": [
      "CINCA syndrome",
      "CINCA/NOMID",
      "IOMID syndrome",
      "NOMID",
      "NOMID syndrome",
      "Neonatal-Onset Multisystem Inflammatory Disease",
      "Prieur-Griscelli syndrome",
      "chronic infantile neurological cutaneous and articular syndrome",
      "chronic neurologic cutaneous and articular syndrome",
      "cryopyrin-associated periodic syndrome 3",
      "infantile-onset multisystem inflammatory disease",
      "neonatal-onset multisystem inflammatory disease",
      "CINCA",
      "Cryopyrin-associated periodic syndrome 3",
      "IOMID",
      "Prieur Griscelli syndrome",
      "infantile onset multisystem inflammatory disease",
      "multisystem inflammatory disease, neonatal-onset",
      "neonatal onset multisystem inflammatory disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4222,
      "label": "musculoskeletal system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:17",
          "EFO:0009676",
          "ICD9:729.99",
          "MEDGEN:6471",
          "MESH:D009140",
          "NCIT:C107377",
          "SCTID:928000",
          "UMLS:C0026857"
        ],
        "synonyms": [
          "disease of musculoskeletal system",
          "disease or disorder of musculoskeletal system",
          "disorder of musculoskeletal system",
          "musculoskeletal disease",
          "musculoskeletal system disease",
          "musculoskeletal system disease or disorder",
          "musculoskeletal system disorder",
          "musculoskeletal disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A disease involving the musculoskeletal system."
      },
      "child_count": 22,
      "reference_id": "MONDO:0002081"
    },
    {
      "id": 16767,
      "label": "cryopyrin-associated periodic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6778,
        18150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010927",
          "ICD9:759.89",
          "MEDGEN:412215",
          "MESH:D056587",
          "MedDRA:10068850",
          "NANDO:1200465",
          "NANDO:2200432",
          "NCIT:C84657",
          "Orphanet:208650",
          "SCTID:430079001",
          "UMLS:C2316212",
          "icd11.foundation:2139918612"
        ],
        "synonyms": [
          "caps",
          "Cryopyrinopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Cryopyrin associated periodic syndrome (CAPS) defines a group of autoinflammatory diseases, characterized by recurrent episodes of systemic inflammatory attacks in the absence of infection or autoimmune disease. CAPS comprises 3 disorders on a continuum of severity: severe CINCA syndrome, intermediate Muckle-Wells syndrome (MWS) and milder familial cold urticaria (FCAS)."
      },
      "child_count": 6,
      "reference_id": "MONDO:0016168"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4222,
      "label": "musculoskeletal system disorder"
    },
    {
      "id": 16767,
      "label": "cryopyrin-associated periodic syndrome"
    }
  ]
}