{
  "id": 7088,
  "label": "treatment-refractory schizophrenia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005414",
  "properties": {
    "xrefs": [
      "EFO:0004609",
      "MEDGEN:1786789",
      "UMLS:C3544321"
    ],
    "synonyms": [
      "TRS",
      "refractory schizophrenia",
      "treatment-refractory schizophrenia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Schizophrenia which does not respond to commonly used treatments."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6817,
      "label": "schizophrenia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7141
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5419",
          "HP:0100753",
          "ICD10CM:F20",
          "ICD10WHO:F20",
          "ICD9:295",
          "ICD9:295.8",
          "ICD9:295.80",
          "ICD9:295.85",
          "ICD9:295.9",
          "ICD9:295.90",
          "MEDGEN:48574",
          "NCIT:C3362",
          "OMIM:181500",
          "Orphanet:3140",
          "SCTID:58214004",
          "UMLS:C0036341",
          "birnlex:2104",
          "icd11.foundation:1683919430"
        ],
        "synonyms": [
          "schizophrenia 12",
          "schizophrenia",
          "schizophrenia (disease)",
          "SCZD",
          "schizoaffective disorder",
          "schizophrenia with or without an affective disorder",
          "schizophrenia, susceptibility to"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005090"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6817,
      "label": "schizophrenia"
    }
  ]
}