{
  "id": 5691,
  "label": "ovarian biphasic or triphasic teratoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0003821",
  "properties": {
    "xrefs": [
      "DOID:6232",
      "GARD:0023684",
      "MEDGEN:274086",
      "NCIT:C39992",
      "UMLS:C1518691"
    ],
    "synonyms": [
      "ovarian biphasic or triphasic teratoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A germ cell tumor that arises from the ovary and is composed of tissues that originate from two or three of the following germ layers, endoderm, ectoderm, or mesoderm."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7245,
      "label": "ovarian teratoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7786,
        12476
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5567",
          "EFO:0006463",
          "GARD:0024209",
          "MEDGEN:76072",
          "NCIT:C8110",
          "SCTID:716077006",
          "UMLS:C0280131",
          "icd11.foundation:1752240825"
        ],
        "synonyms": [
          "germ cell teratoma of ovary",
          "germ cell teratoma of the ovary",
          "ovarian germ cell teratoma",
          "ovarian teratoma",
          "teratoma of ovary",
          "teratoma of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-seminomatous germ cell tumor arising from the ovary. It is characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). According to the level of differentiation of the tissues which comprise the tumor, ovarian teratomas are classified as mature or immature. Mature teratomas are composed of well differentiated, adult-type tissues. Immature teratomas are composed of immature, fetal type-tissues. Mature ovarian teratomas without a fetal-type component have an excellent outcome. The prognosis of immature ovarian teratomas is related to the grade and stage of the tumor."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005602"
    }
  ],
  "children": [
    {
      "id": 5690,
      "label": "mature ovarian teratoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5430,
        5691
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6231",
          "GARD:0023683",
          "MEDGEN:233672",
          "NCIT:C8112",
          "ONCOTREE:OMT",
          "UMLS:C1334637"
        ],
        "synonyms": [
          "mature ovarian teratoma",
          "mature teratoma of ovary",
          "ovary mature teratoma",
          "mature teratoma",
          "mature teratoma of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An ovarian teratoma which may be cystic, composed entirely of well differentiated, adult-type tissues, without evidence of fetal-type tissues."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003820"
    },
    {
      "id": 18450,
      "label": "immature ovarian teratoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5427,
        5691,
        16723
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6331",
          "GARD:0021654",
          "MEDGEN:138044",
          "NCIT:C39995",
          "NCIT:C8111",
          "ONCOTREE:OIMT",
          "Orphanet:398987",
          "SCTID:254871000",
          "UMLS:C0346182",
          "icd11.foundation:551209361"
        ],
        "synonyms": [
          "immature germ cell teratoma of ovary",
          "immature germ cell teratoma of the ovary",
          "immature ovarian teratoma",
          "immature teratoma of ovary",
          "immature teratoma of the ovary",
          "malignant germ cell teratoma of ovary",
          "malignant germ cell teratoma of the ovary",
          "malignant ovarian germ cell teratoma",
          "malignant ovarian teratoma",
          "malignant teratoma of ovary",
          "malignant teratoma of the ovary",
          "ovarian germ cell immature teratoma",
          "ovarian immature germ cell teratoma",
          "ovarian immature teratoma",
          "ovarian malignant teratoma",
          "ovary malignant teratoma",
          "immature teratoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant germ cell tumor arising from the ovary. It usually affects females in their first two decades of life. It contains variable amounts of immature embryonal tissues. Based on the amount of immature neuroepithelial component, immature teratomas are graded from 1 to 3. The stage and grade of the tumor and the grade of the metastatic tumor are the important factors that predict prognosis. The use of cisplatin-based combination chemotherapy has significantly improved the survival rates of the patients."
      },
      "child_count": 6,
      "reference_id": "MONDO:0018369"
    }
  ],
  "roots": [
    {
      "id": 7245,
      "label": "ovarian teratoma"
    }
  ]
}