{
  "id": 4841,
  "label": "acute myocarditis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002815",
  "properties": {
    "xrefs": [
      "DOID:3951",
      "GARD:0023253",
      "ICD10WHO:I40",
      "ICD9:422",
      "ICD9:422.90",
      "ICD9:422.99",
      "MEDGEN:102339",
      "NCIT:C35206",
      "SCTID:46701001",
      "UMLS:C0155686"
    ],
    "synonyms": [
      "myocarditis, acute"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "The sudden onset of inflammation of heart muscle with myocellular necrosis; this is generally secondary to an infectious cause, and patients often have a recent history of a flu-like illness."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6298,
      "label": "myocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3007,
        21547,
        21552
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:820",
          "EFO:0009609",
          "GARD:0007137",
          "ICD10CM:I40",
          "ICD9:429.0",
          "MEDGEN:44553",
          "MESH:D009205",
          "NCIT:C34831",
          "NORD:1882",
          "SCTID:50920009",
          "UMLS:C0027059",
          "icd11.foundation:1018829714"
        ],
        "synonyms": [
          "inflammation of myocardium",
          "myocardial inflammation (finding)",
          "myocardium inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Myocarditis is a condition that is characterized by inflammation of the heart muscle (myocardium). Some affected people have no noticeable symptoms of the condition. When present, signs and symptoms may include chest pain, abnormal heartbeat, shortness of breath, fatigue, signs of infection (i.e. fever, headache, sore throat, diarrhea), and leg swelling. Myocarditis can be caused by a variety of factors including infections (viral, bacterial, parasitic, and fungal), allergic reactions to certain medications, and exposure to certain chemicals. It can also be associated with other inflammatory conditions such as lupus, Wegener's granulomatosis, giant cell arteritis and Takayasu's arteritis. Most cases occur sporadically in people with no family history of the condition. Treatment aims to address the underlying cause of the condition. Medications and rarely, a heart transplant may be needed if the heart muscle becomes weak."
      },
      "child_count": 21,
      "reference_id": "MONDO:0004496"
    },
    {
      "id": 20092,
      "label": "acute disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24492
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:1738",
          "MESH:D000208",
          "SCTID:2704003",
          "UMLS:C0001314"
        ],
        "synonyms": [
          "acute disease",
          "acute diseases",
          "disease, acute"
        ],
        "definition": "Disease having a short and relatively severe course."
      },
      "child_count": 119,
      "reference_id": "MONDO:0020683"
    }
  ],
  "children": [
    {
      "id": 6607,
      "label": "toxic myocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9694",
          "GARD:0024118",
          "ICD9:422.93",
          "MEDGEN:510049",
          "SCTID:31993003",
          "UMLS:C0155691"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0004851"
    },
    {
      "id": 21192,
      "label": "giant cell myocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0006502",
          "NCIT:C97055",
          "NORD:1183",
          "SCTID:60812006",
          "icd11.foundation:507103735"
        ],
        "synonyms": [
          "giant cell myocarditis",
          "GCM",
          "idiopathic giant-cell myocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An often fatal inflammatory disorder that affects the myocardium. Morphologically, it is characterized by the presence of an inflammatory infiltrate in the myocardial tissue that includes multinucleated giant cells. It is often associated with the presence of an autoimmune disorder. Patients present with arrhythmias and/or heart failure. Heart transplantation is the only treatment option available."
      },
      "child_count": 1,
      "reference_id": "MONDO:0023232"
    }
  ],
  "roots": [
    {
      "id": 6298,
      "label": "myocarditis"
    },
    {
      "id": 20092,
      "label": "acute disease"
    }
  ]
}